Results 241 to 250 of about 12,043,245 (295)
Some of the next articles are maybe not open access.
The Anatomical Record, 1969
AbstractIn the course of ultrastructural studies on the cerebellar cortex of young rats a cilium was found in some Purkinje cells. The shaft, which is 1800 to 2000 ÅR thick, has an internal portion inside the cell body and an external one projecting into the neuropile. The basal body is consistently located near the Golgi apparatus.
Manuel P. Del Cerro +2 more
openaire +2 more sources
AbstractIn the course of ultrastructural studies on the cerebellar cortex of young rats a cilium was found in some Purkinje cells. The shaft, which is 1800 to 2000 ÅR thick, has an internal portion inside the cell body and an external one projecting into the neuropile. The basal body is consistently located near the Golgi apparatus.
Manuel P. Del Cerro +2 more
openaire +2 more sources
Cardiac Purkinje cells in culture
Journal of Molecular and Cellular Cardiology, 1983Purkinje cells from false tendons of young rabbits, pigs and fetal lambs were dispersed by the action of collagenase and elastase and grown in culture for up to 14 days. Immunofluorescent staining with fluorescein-labelled antibodies to cardiac myosin and tropomyosin demonstrated cross-banding and/or a diffuse positive stain in Purkinje cells between 3
Canale, E, Campbell, JH, Campbell, GR
openaire +3 more sources
Anatomy embroiders function in Purkinje cells
The Lancet Neurology, 2021The anatomy of the human cerebellar Purkinje cell, as captured by Ramón y Cajal in a drawing, inspired the spectacular cover embroidery by Lisa Stoneman (Roanoke College, Roanoke, VA, USA) in the October issue of The Lancet Neurology. 1 Like contemporary confocal microscopy images do, this anatomical representation also raises fascinating questions ...
Attwell, David, Mehta, Arpan R
openaire +3 more sources
Purkinje Cell Transplants inShakerMutant Rats with Hereditary Purkinje Cell Degeneration and Ataxia
Experimental Neurology, 1998Shaker mutant rats are characterized by the adult-onset degeneration of cerebellar anterior lobe Purkinje cells and temporally correlated development of ataxia and tremor. Normal E-13 Purkinje cells were transplanted into the anterior cerebellum in adult shaker mutant rats to study donor/host interactions in an animal with adult-onset ...
D L, Tolbert, J, Heckroth
openaire +2 more sources
1974
The apparent simplicity of the cerebellar cortex reflects in part the small number of neuronal types comprised in it. Most descriptions credit it with only five types of nerve cells: Purkinje cells, granule cells, basket cells, stellate cells, and Golgi cells.
Sanford L. Palay, Victoria Chan-Palay
openaire +1 more source
The apparent simplicity of the cerebellar cortex reflects in part the small number of neuronal types comprised in it. Most descriptions credit it with only five types of nerve cells: Purkinje cells, granule cells, basket cells, stellate cells, and Golgi cells.
Sanford L. Palay, Victoria Chan-Palay
openaire +1 more source
Sodium channels in cardiac Purkinje cells
Experientia, 1987Sodium (Na+) currents are responsible for excitation and conduction in most cardiac cells, but their study has been hampered by the lack of a satisfactory method for voltage clamp. We report a new method for low resistance access to single freshly isolated canine cardiac Purkinje cells that permits good control of voltage and intracellular ionic ...
H A, Fozzard +4 more
openaire +2 more sources
Purkinje Cell Migration and Differentiation
2013The Purkinje cell is the pivotal element of the cerebellar network, which integrates distinct extracerebellar inputs and generates the ultimate cortical output to be conveyed to the deep cerebellar nuclei. During development, the adult Purkinje cell phenotype is acquired through a complex sequence of ontogenetic processes, including migration from the ...
Sotelo C, ROSSI, Ferdinando
openaire +2 more sources
Purkinje cell activity during motor learning
Brain Research, 1977Monkeys were trained to grasp a handle and move it in a horizontal arc to a central position by flexing or extending the wrist. A torque motor applied forces to the handle that switched at random intervals to alternately load flexor and extensor muscles. At each load switch, the handle was displaced transiently from the central position, and then moved
P F, Gilbert, W T, Thach
openaire +2 more sources
Heterotopic Purkinje cells in ataxia‐telangiectasia
Neuropathology, 2011Ataxia‐telangiectasia (A‐T) is a heritable disorder of cerebellar ataxia and oculocutaneous telangiectasias caused by mutation of the ATM gene. The most prominent and consistent neuropathologic finding in the disorder is cerebellar cortical degeneration involving significant loss of granule and Purkinje cells.
Alexander R, Bottini +3 more
openaire +2 more sources
Cardiovascular Engineering and Technology, 2020
The objective of this study was to reprogram human adipogenic mesenchymal stem cells (hADMSCs) to form Purkinje cells and to use the reprogrammed Purkinje cells to bioprint Purkinje networks.hADMSCs were reprogrammed to form Purkinje cells using a multi-step process using transcription factors ETS2 and MESP1 to first form cardiac progenitor stem cells ...
Evan P, Tracy +5 more
openaire +2 more sources
The objective of this study was to reprogram human adipogenic mesenchymal stem cells (hADMSCs) to form Purkinje cells and to use the reprogrammed Purkinje cells to bioprint Purkinje networks.hADMSCs were reprogrammed to form Purkinje cells using a multi-step process using transcription factors ETS2 and MESP1 to first form cardiac progenitor stem cells ...
Evan P, Tracy +5 more
openaire +2 more sources