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Cardiac Purkinje cells

Heart Rhythm, 2010
Purkinje cells are specialized for rapid propagation in the heart. Furthermore, Purkinje fibers as the source as well as the perpetuator of arrhythmias is a familiar finding. This is not surprising considering their location in the heart and their unique cell ultrastructure, cell electrophysiology, and mode of excitation-contraction coupling.
Wen Dun, Penelope A Boyden
exaly   +3 more sources

The Purkinje cell; 2008 style [PDF]

open access: yesJournal of Molecular and Cellular Cardiology, 2008
Cardiac Purkinje fibers, due to their unique anatomical location, cell structure and electrophysiologic characteristics, play an important role in cardiac conduction and arrhythmogenesis. Purkinje cell action potentials are longer than their ventricular counterpart, and display two levels of resting potential.
Wen Dun, Penelope A Boyden
exaly   +3 more sources

THE FINE STRUCTURE OF THE PURKINJE CELL [PDF]

open access: yesJournal of Cell Biology, 1963
This paper describes the fine structure of the Purkinje cell of the rat cerebellum after fixation by perfusion with 1 per cent buffered osmium tetroxide. Structures described include a large Golgi apparatus, abundant Nissl substance, mitochondria, multivesicular bodies, osmiophilic granules, axodendritic and axosomatic synapses, the nucleus, the ...
Robert M Herndon, R M Herndon
exaly   +3 more sources

The purkinje cell cilium

The Anatomical Record, 1969
AbstractIn the course of ultrastructural studies on the cerebellar cortex of young rats a cilium was found in some Purkinje cells. The shaft, which is 1800 to 2000 ÅR thick, has an internal portion inside the cell body and an external one projecting into the neuropile. The basal body is consistently located near the Golgi apparatus.
Manuel P. Del Cerro   +2 more
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Cardiac Purkinje cells in culture

Journal of Molecular and Cellular Cardiology, 1983
Purkinje cells from false tendons of young rabbits, pigs and fetal lambs were dispersed by the action of collagenase and elastase and grown in culture for up to 14 days. Immunofluorescent staining with fluorescein-labelled antibodies to cardiac myosin and tropomyosin demonstrated cross-banding and/or a diffuse positive stain in Purkinje cells between 3
Canale, E, Campbell, JH, Campbell, GR
openaire   +6 more sources

Motilin in the Purkinje cell of the cerebellum

Nature, 1982
None of the brain peptides has been demonstrated to be present in significant amounts in the cerebellum1,2. The only effector substance known in the Purkinje cell, whose axon carries the integrated output of the cerebellar cortex, is the decarboxylated residue of glutamic acid3–6.
G, Nilaver   +4 more
openaire   +2 more sources

Aging of cerebellar Purkinje cells

Cell and Tissue Research, 2010
Cerebellar Purkinje cells (PCs), the sole output neurons in the cerebellar cortex, play an important role in the cerebellar circuit. PCs appear to be rather sensitive to aging, exhibiting significant changes in both morphology and function during senescence.
Changzheng, Zhang   +2 more
openaire   +2 more sources

The Purkinje Cell

1974
The apparent simplicity of the cerebellar cortex reflects in part the small number of neuronal types comprised in it. Most descriptions credit it with only five types of nerve cells: Purkinje cells, granule cells, basket cells, stellate cells, and Golgi cells.
Sanford L. Palay, Victoria Chan-Palay
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