Results 231 to 240 of about 4,781,201 (273)
Some of the next articles are maybe not open access.
Purkinje Cell Transplants inShakerMutant Rats with Hereditary Purkinje Cell Degeneration and Ataxia
Experimental Neurology, 1998Shaker mutant rats are characterized by the adult-onset degeneration of cerebellar anterior lobe Purkinje cells and temporally correlated development of ataxia and tremor. Normal E-13 Purkinje cells were transplanted into the anterior cerebellum in adult shaker mutant rats to study donor/host interactions in an animal with adult-onset ...
D L, Tolbert, J, Heckroth
openaire +2 more sources
Excitatory synaptic currents in Purkinje cells
Proceedings of the Royal Society of London. Series B: Biological Sciences, 1990The N-methyl-D-aspartate (NMDA) and non-NMDA classes of glutamate receptor combine in many regions of the central nervous system to form a dual-component excitatory postsynaptic current. Non-NMDA receptors mediate synaptic transmission at the resting potential, whereas NMDA receptors contribute during periods of postsynaptic depolarization and play a ...
Perkel, DJ +3 more
openaire +5 more sources
Acta Neuropathologica, 1982
Purkinje cells from five autopsy cases (a premature newborn infant, a GM1-gangliosidosis, an olivo-ponto-cerebellar atrophy, a multisystem atrophy involving the spinal cord and the brain stem, and a woman of 82 years) were studied using the Golgi impregnation technique.
K, Fujisawa, A, Nakamura
openaire +2 more sources
Purkinje cells from five autopsy cases (a premature newborn infant, a GM1-gangliosidosis, an olivo-ponto-cerebellar atrophy, a multisystem atrophy involving the spinal cord and the brain stem, and a woman of 82 years) were studied using the Golgi impregnation technique.
K, Fujisawa, A, Nakamura
openaire +2 more sources
2000
Abstract Jan Evangelista Purkinje (Purkyne) was born in 1787, in the castle of Libochovice, Bohemia, where his father acted as the estate manager. He received his first formal education at the Gymnasium connected to the monastery of the Fratres piarum scholarum, in Mikulov, South Moravia, and later joined this order. After completing his
openaire +1 more source
Abstract Jan Evangelista Purkinje (Purkyne) was born in 1787, in the castle of Libochovice, Bohemia, where his father acted as the estate manager. He received his first formal education at the Gymnasium connected to the monastery of the Fratres piarum scholarum, in Mikulov, South Moravia, and later joined this order. After completing his
openaire +1 more source
Purkinje Cells and their Responses
1967In Chapter I there is an extensive account of the structural features of the most remarkable elements of the cerebellar cortex, the Purkinje cells, and in Chapter III there is a full description of the synapses that parallel fibers make with the spiny branchlets of Purkinje cell dendrites.
John C. Eccles +2 more
openaire +1 more source
Axonal abnormalities in cerebellar Purkinje cells of the ?hyperspiny Purkinje cell? mutant mouse
Journal of Neurocytology, 1990The hyperspiny Purkinje cell (hpc) is a murine, autosomal recessive mutation affecting cerebellar Purkinje cells. Axonal abnormalities in these neurons have been revealed by selective silver impregnation, specific immunohistochemical staining and electron microscopy.
openaire +2 more sources
Cell Counts of Purkinje and Inferior Olivary Neurons in the ‘Hyperspiny Purkinje Cells’ Mutant Mouse
European Journal of Neuroscience, 1992AbstractThe mutant mouse ‘hyperspiny Purkinje cells’(hpc) has morphologically abnormal Purkinje cells and below normal intracerebellar calbindin‐D28k, a calcium‐binding protein that, in the cerebellum, is found only in the Purkinje cells. We counted the Purkinje cells on serial sections stained with thionin or labelled with anti‐calbindin‐D28k ...
F., Frederic +5 more
openaire +2 more sources
A computer model of cerebellar purkinje cells
Neuroscience, 1977Abstract A mathematical computer model of frog Purkinje cells is generated on the basis of presentday morphological and physiological data. The model utilizes passive cable equations and the Hodgkin & Huxley equations describing ionic conductances in excitable membranes.
A, Pellionisz, R, Llinás
openaire +2 more sources
Purkinje cell activation by stimulation of the labyrinth
Pfl�gers Archiv European Journal of Physiology, 1970Caloric and galvanic stimulation of the labyrinth can modulate the activity of the Purkinje cells of the cerebellum through both mossy fibre and climbing fibre systems. The former system is modulated in a higher frequency range than the latter. These results were obtained mainly in the vestibular area, but they were also present in other areas of the ...
M, Ferin, R A, Grigorian, P, Strata
openaire +2 more sources
Neuroscience Gateway, 2006
Compromised glutamate transport in Bergmann glia contributes to Purkinje cell death in a model of spinal cerebellar ataxia.
openaire +1 more source
Compromised glutamate transport in Bergmann glia contributes to Purkinje cell death in a model of spinal cerebellar ataxia.
openaire +1 more source