Results 131 to 140 of about 126,114 (304)
AcPhe-puromycin synthesis in the presence or absence of compound 5.
, 2015 (A) First-order time plots; complex C reacted at 25°C in buffer A, with (black) 400 μM puromycin or with a mixture containing 400 μM puromycin and compound 5 at concentrations of 4 μM (magenta), 8 μM (green), 15 μM (blue), and 30 μM (red).
Dimitrios L. Kalpaxis (9161) +6 more
core +1 more source
, 1990 The hypothesis was tested that the renal xanthine oxidase system provides a source of oxygen free radicals in puromycin aminonucleoside and adriamycin experimental nephrosis by generating uric acid from hypoxanthine and xanthine.
D(')Allegri, F. +9 more
core +2 more sources
Advanced Science, EarlyView.Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye +9 more
wiley +1 more source
Synthesis of Conformationally Locked Versions of Puromycin Analogues
, 2016 Conformationally locked North and South versions of puromycin analogues built on a bicyclo[3.1.0]hexane pseudosugar template were synthesized. The final assembly of the products was accomplished by the Staudinger−Vilarrasa coupling of the corresponding ...
Yongseok Choi (820358) +4 more
core +1 more source
Optical Control of Translation with a Puromycin Photoswitch
Translation is an elementary cellular process that involves a large number of factors interacting in a concerted fashion with the ribosome. Numerous natural products have emerged that interfere with the ribosomal function, such as puromycin, which mimics
Mauricio M. Oliveira (12979512) +5 more
core +2 more sources
Advanced Science, EarlyView.HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li +13 more
wiley +1 more source
Advanced Science, Volume 13, Issue 36, 29 June 2026.The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
Cytogenetic analysis of human oocytes parthenogenetically activated by puromycin
, 1994 Purpose: Treatment of aged human oocytes by puromycin allows a high rate of parthenogenetic activation and development until the first cleavage division.
Desmet, R +4 more
core
Triptolide protects podocytes from puromycin aminonucleoside induced injury in vivo and in vitro
, 2008 Extracts of Tripterygium wilfordii Hook F have been used to treat glomerulonephritis for more than 30 years in China with dramatic antiproteinuric effects. Triptolide, a diterpene triepoxide, is one of the major active components of these extracts.
Zheng, Chun-Xia +5 more
core +1 more source
Modified polymeric biomaterials with antimicrobial and immunomodulating properties
Scientific ReportsThe modification of the surgical polypropylene mesh and the polytetrafluoroethylene vascular prosthesis with cecropin A (small peptide) and puromycin (aminonucleoside) yielded very stable preparations of modified biomaterials.
Katarzyna Szałapata +13 more
doaj +1 more source