Results 201 to 210 of about 122,814 (265)

Human pluripotent stem cell engineering with CRISPR-Cas9 for Parkinson's disease. [PDF]

Exp Mol Med
Park SB, Kim JS, Ha Y, Kim MS, Kim TW.
europepmc   +1 more source

Intratumoral Hypoxia Triggers Mitochondrial BHLHE40 ROS Sensing Pathway to Promote Radioresistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu, Ziliang Nie, Xi Chen, Guangyu Ji, Yajing Zhang, Zhiqun Zhao, Yuhong Zhang, Xinlong Du, Zhenzhen Zhou, Jiayi Li, Yaozong Yang, Fengqi Sun, Zhibo Yan, Haiquan Lu   +13 more
wiley   +1 more source

lncRNA-operated stem cell fate control: RPS3 mediates the in situ Gm16751-Zhx3 interactome to program spermatogonial stem cell differentiation. [PDF]

Cell Biosci
Gao W, Xu B, Ma W, He X, Wu J.
europepmc   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source

Predifferentiation Neurotoxicity of GenX Exposure on hiPSC-Derived Cortical Neurons. [PDF]

Environ Sci Technol
Wu S, Xie J, Zhao X, Zhao H, Sánchez OF, Yu S, Rochet JC, Freeman JL, Yuan C.   +8 more
europepmc   +1 more source

Protocol for Using CRISPR-Cas9 to Generate a Monocyte Cell Line Harboring a Single-Nucleotide Polymorphism. [PDF]

Bio Protoc
Mahatha AC, Ramos-Espinosa O, de Lima DS, Liu EY, Vaidyan S, Liu J.   +5 more
europepmc   +1 more source

Interaction of puromycin and puromycin aminonucleoside with poly (A)--a proton magnetic resonance investigation.

Indian journal of biochemistry & biophysics, 1987
M M, Dhingra, S S, Narula
openaire   +1 more source

Chronic stress antagonizes formation of stress granules. [PDF]

iScience
Adachi Y, Williams AM, Masuda M, Taketani Y, Anderson PJ, Ivanov P.   +5 more
europepmc   +1 more source

U2AF regulates the translation and localization of nuclear-encoded mitochondrial mRNAs. [PDF]

Mol Cell
Garcia GR, Palangat M, Moraly J, Donovan BT, Wang B, Phadke I, Sturgill D, Chen J, Zhang G, Holewinski RJ, Short B, Rivero GA, Swoboda DM, Taylor N, McGraw K, Larson DR.   +15 more
europepmc   +1 more source

Lactate supplementation modulates molecular and functional responses during chronic neuromuscular electrical stimulation in male rats. [PDF]

Physiol Rep
Yoshihara T, Koriyama Y, Ogawa S, Naito H.   +3 more
europepmc   +1 more source