Results 241 to 250 of about 159,015 (286)

Methylophiopogonanone a attenuates pulmonary fibrosis by inhibiting SPP1‐mediated macrophage polarization via the PI3K/Akt pathway

Animal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing identified secreted phosphoprotein 1 (SPP1) as a crucial target through which methylophiopogonanone A (MOA) ameliorates pulmonary fibrosis. Molecular docking and microscale thermophoresis (MST) assays confirmed a favorable binding affinity between MOA and SPP1.
Fan Yang, Tian Li, Weiran Jia, Dingjie Xu, Liangdan Sun, Yanlei Ge, Yiwei Shi, Hong Xu, Xudong Song, Fuyu Jin, Na Mao   +10 more
wiley   +1 more source

Dileucine-supplemented essential amino acids support whole-body anabolism after resistance exercise and serum-stimulated cell-based anabolism. [PDF]

J Int Soc Sports Nutr
Aguilera JA, Tinline-Goodfellow CT, Lees MJ, Kortebi I, West DWD, Abou Sawan S, Sharma M, Bashir R, Barnes TM, Ulanov AV, Burd NA, Moore DR.   +11 more
europepmc   +1 more source

A cell line development vector strategy for improved expression of a trispecific T-cell engager in CHO. [PDF]

MAbs
Mistry RK, Nui C, Lambiase G, Ray D, Kearsey L, Hitchcock N, Grassi L, Elgendy R, Fleming J, Broughton AC, Zhao P, Chiang CI, Shah P, Cyr M, Walseng E, Mazor Y, Hatton D, Dunn S.   +17 more
europepmc   +1 more source

Proximity Labeling Reveals RNA-Binding Proteins Associating with the Human Mitochondrial Import Receptor TOMM20. [PDF]

J Proteome Res
Akram S, Zittlau KI, Sharma K, Fitzgerald JC, Rafiq N, Maček B, Jansen RP.   +6 more
europepmc   +1 more source

Metabolic quiescence of naive-like memory T cells precedes and maintains antigen-specific T cell memory. [PDF]

Nat Immunol
Frischholz S, Schuster EM, Grotz M, Schülein C, Benz J, Kocher K, Klotz L, Varga S, Hiltner T, Alsalameh R, Esse J, Träger J, Held J, Graw F, Pahle J, Spriewald B, Gattinoni L, Buchholz VR, Drost F, Schubert B, Rothenfußer S, Busch DH, Bogdan C, Schober K.   +23 more
europepmc   +1 more source

CDK4/6 inhibition overcomes venetoclax resistance mechanisms with enhanced combination activity in acute myeloid leukemia. [PDF]

Cell Rep Med
Stewart ML, Gibbs J, Watanabe-Smith K, Nguyen A, Kenna I, Thiel-Klare K, Kaempf A, Bottomly D, Kurtz SE, Eide CA, Long N, Saultz JN, Sax L, Huang A, McWeeney SK, Chang BH, Tyner JW.   +16 more
europepmc   +1 more source

Propofol attenuates angiogenesis by activating endoplasmic reticulum stress to suppress TFAP2C-driven VEGFA transcription. [PDF]

Apoptosis
Yang F, Liu Y, Li H, Shang X, Hua Q, Zhu Y, Tao B, Sun Z.   +7 more
europepmc   +1 more source

Genetic Engineering of Humanized Telomere Mice. [PDF]

Bio Protoc
Zhang F, Cheng, Porter KI, Wang S, Zhu J.   +4 more
europepmc   +1 more source