Results 101 to 110 of about 103,888 (259)
Pediatric thrombotic thrombocytopenic purpura
Child‐onset thrombotic thrombocytopenic purpura (TTP) is a rare entity of thrombotic microangiopathy (TMA). The pathophysiology of the disease is based on a severe functional deficiency of ADAMTS13 (activity
B. Joly, P. Coppo, A. Veyradier
semanticscholar +1 more source
NEONATAL THROMBOCYTOPENIC PURPURA: REPORT OF TWO CASES AND REVIEW OF LITERATURE [PDF]
Introduction: Severe neonatal thrombocytopenia is a hematological emergency that can be due to increased platelet destruction (such as immune-mediated and peripheral platelet consumption) or congenital failure of platelet production.
Abiodun MT, Badejoko B, Oluwafemi RO
doaj
Aplastic Crisis as Primary Manifestation of Systemic Lupus Erythematosus [PDF]
Aplastic crisis is an unusual feature of systemic lupus erythematosus (SLE). We report the case of a 54-year-old woman presenting with both (extravascular) Coombs-positive hemolytic anemia and laboratory findings of bone marrow hyporegeneration with ...
Alger M +23 more
core +1 more source
Associated Autoimmunity in Myasthenia Gravis in Denmark: A Nationwide Case–Control Study
Myasthenia gravis (MG) often co‐occurs with other autoimmune diseases (ADs), but the temporal relationship is unclear. In this study, patients were twice as likely to have another AD, particularly females aged ≤ 50 years, suggesting a shared autoimmunity and a call for clinical awareness.
Josefine Jul Jarbæk Nielsen +2 more
wiley +1 more source
Essentials Acquired thrombotic thrombocytopenic purpura (aTTP) is linked with significant morbidity/mortality. Caplacizumab's effect on major thromboembolic (TE) events, exacerbations and death was studied. Fewer caplacizumab‐treated patients had a major
F. Peyvandi +8 more
semanticscholar +1 more source
Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia. [PDF]
The activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease is low in several conditions, including HELLP (haemolysis, elevated liver enzymes, and low platelet count) syndrome.
Bõze, Tamás +9 more
core +1 more source
Thrombotic thrombocytopenic purpura [PDF]
Thrombotic thrombocytopenic purpura (TTP) is a clearly defined entity of the thrombotic microangiopathies (TMA), a heterogeneous group of disorders characterized by microangiopathic hemolytic anemia with red cell fragmentation, thrombocytopenia and organ dysfunction due to disturbed microcirculation.
openaire +2 more sources
Abstract Background Studies suggest an increase in autoimmune diseases following SARS‐CoV‐2 infection and/or COVID‐19‐vaccination. We aimed to describe possible associations in Norway. Methods We used information from the emergency preparedness register for COVID‐19, BeredtC19, for all residents aged 18–64 (N = 3,450,080).
Håkon Bøås +4 more
wiley +1 more source
Refractory Immune Thrombocytopenia Successfully Treated with High-Dose Vitamin D Supplementation and Hydroxychloroquine: Two Case Reports [PDF]
Introduction: Immune thrombocytopenic purpura is thought to be characterized by an immune response against the host’s own platelets. If the thrombocytopenia is severe, patients are initially treated with high-dose steroids.
Bockow, Barry, Bockow, Tamara B
core +1 more source
Immune thrombocytopenia (ITP) is an autoimmune disease that causes a drop in platelet count
Giuseppe Auteri +3 more
doaj +1 more source

