Results 71 to 80 of about 79,367 (221)

Evaluating the appropriateness of fresh frozen plasma transfusions in two tertiary teaching hospitals

Transfusion Medicine, EarlyView.
Abstract Background Despite efforts to standardise practice using evidence‐based guidelines, fresh frozen plasma (FFP) remains the blood component most frequently prescribed inappropriately. This study assessed the appropriateness of FFP transfusion in two tertiary teaching hospitals and analysed the characteristics of appropriate and inappropriate ...
Jongmin Kim, Kae Lyang Koo, Hyun‐Ji Lee, Hyung‐Hoi Kim   +3 more
wiley   +1 more source

Wiskott–Aldrich syndrome that was initially diagnosed as immune thrombocytopenic purpura secondary to a cytomegalovirus infection

SAGE Open Medical Case Reports, 2018
Wiskott–Aldrich syndrome is a rare X-linked recessive disease resulting from variations in the WAS gene. Wiskott–Aldrich syndrome is sometimes difficult to differentiate from immune thrombocytopenic purpura. A 2-month-old boy was admitted to our hospital
Ryota Kaneko, Shohei Yamamoto, Naoko Okamoto, Kosuke Akiyama, Ryosuke Matsuno, Daisuke Toyama, Akihiro Hoshino, Kohsuke Imai, Keiichi Isoyama   +8 more
doaj   +1 more source

Disintegrin‐Like and Metalloprotease With Thrombospondin Type 1 Repeat Motifs 13 (ADAMTS13) Activity in 40 Healthy Dogs

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Background In humans, deficiency of a disintegrin‐like and metalloprotease with thrombospondin type 1 motifs, number 13 (ADAMTS13), a von Willebrand factor (vWF) cleaving protease, is an underlying mechanism for thrombosis. The role of ADAMTS13 in canine thromboembolic disease is largely unknown.
Ashley R. Wilkinson, Priscila Beatriz da Silva Serpa, S. Michelle Todd   +2 more
wiley   +1 more source

ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission

Haematologica, 2008
Background From 20 to 50% of patients who survive an acute episode of the acquired form of thrombotic thrombocytopenic purpura relapse but clinical and laboratory markers of recurrence are not well established.Design and Methods In 109 patients enrolled ...
Flora Peyvandi, Silvia Lavoretano, Roberta Palla, Hendrik B. Feys, Karen Vanhoorelbeke, Tullia Battaglioli, Carla Valsecchi, Maria Teresa Canciani, Fabrizio Fabris, Samo Zver, Marienn Réti, Danijela Mikovic, Mehran Karimi, Gaetano Giuffrida, Luca Laurenti, Pier Mannuccio Mannucci   +15 more
doaj   +1 more source

Anti‐ADAMTS13 Antibodies Trajectory is Associated With ADAMTS13 Recovery in Immune‐Mediated TTP

American Journal of Hematology, Volume 100, Issue 10, Page 1736-1746, October 2025.
Anti‐ADAMTS13 IgG antibodies titer trajectory from baseline to day 7–14 post‐TPE as a reliable approach to identify iTTP patients at risk of late response to the triplet therapy regimen. ABSTRACT Current triplet regimens associating therapeutic plasma exchange (TPE), immunosuppression with corticosteroids and rituximab, and caplacizumab have ...
Marie Robert, Arthur Mageau, Ygal Benhamou, François Provôt, Jehane Fadlallah, Lionel Galicier, Elie Azoulay, Hafid Ait‐Oufella, Tomas Urbina, Pascale Poullin, Alain Wynckel, Coralie Poulain, Nihal Martis, Pierre Perez, Virginie Rieu, Yahsou Delmas, Jean‐Michel Halimi, Christelle Barbet, Amélie Seguin, Valérie Chatelet, Jean‐François Augusto, Mathieu Legendre, Olivier Moranne, Carole Philipponnet, Bérengère Cador, Raïda Bouzid, Bérangère S. Joly, Agnès Veyradier, Paul Coppo, on behalf of the French Reference Center for Thrombotic Microangiopathies, Augusto Jean‐François, Azoulay Elie, Barbay Virginie, Benhamou Ygal, Charasse Christophe, Charvet‐Rumpler Anne, Chauveau Dominique, Ribes Davis, Choukroun Gabriel, Coindre Jean‐Philippe, Coppo Paul, Delmas Yahsou, Kwon Theresa, Salanoubat Célia, Dossier Antoine, Fain Olivier, Ville Simon, Frémeaux‐Bacchi Véronique, Galicier Lionel, Grangé Steven, Guidet Bertrand, Halimi Jean‐Michel, Hamidou Mohamed, Neel Antoine, Fornecker Luc‐Matthieu, Hié Miguel, Jacobs Frédéric, Joly Bérangère, Kanouni Tarik, Kaplanski Gilles, Rieu Claire, Le Guern Véronique, Moulin Bruno, Rebibou Jean‐Michel, Ojeda Uribe Mario, Parquet Nathalie, Pène Frédéric, Perez Pierre, Poullin Pascale, Marie Manon, Presne Claire, Provôt François, Mesnard Laurent, Saheb Samir, Seguin Amélie, Servais Aude, Stépanian Alain, Veyradier Agnès, Vigneau Cécile, Wynckel Alain, Zunic Patricia   +80 more
wiley   +1 more source

NEONATAL THROMBOCYTOPENIC PURPURA: REPORT OF TWO CASES AND REVIEW OF LITERATURE [PDF]

Kanem Journal of Medical Sciences, 2018
Introduction: Severe neonatal thrombocytopenia is a hematological emergency that can be due to increased platelet destruction (such as immune-mediated and peripheral platelet consumption) or congenital failure of platelet production.
Abiodun MT, Badejoko B, Oluwafemi RO
doaj  

Trastuzumab Deruxtecan for Human Epidermal Growth Factor Receptor 2‐Low Breast Cancer With Cancer‐Related Microangiopathic Hemolytic Anemia: A Case Report

Cancer Innovation, Volume 4, Issue 5, October 2025.
The diagnosis and treatment of acquired hemolytic anemia can be challenging. In breast cancer patients, it may be directly associated with the underlying malignancy (as an initial presentation or during disease progression). The diagnosis of cancer‐related microangiopathic hemolytic anemia (CR‐MAHA) is often delayed, and patients have a high mortality ...
Mengyuan Li, Mao Ding, Yukun Hou, Xuening Duan, Yuanjia Cheng, Ling Xu   +5 more
wiley   +1 more source

Long-term Kidney Outcomes in Patients With Acquired Thrombotic Thrombocytopenic Purpura

Kidney International Reports, 2017
Severe acute kidney injury (AKI) and chronic kidney disease (CKD) are considered to be uncommon in patients with acquired thrombotic thrombocytopenic purpura.
Dustin J. Little, Lauren M. Mathias, Evaren E. Page, Johanna A. Kremer Hovinga, Sara K. Vesely, James N. George   +5 more
doaj   +1 more source

Caplacizumab reduces the frequency of major thromboembolic events, exacerbations and death in patients with acquired thrombotic thrombocytopenic purpura

Journal of Thrombosis and Haemostasis, 2017
Essentials Acquired thrombotic thrombocytopenic purpura (aTTP) is linked with significant morbidity/mortality. Caplacizumab's effect on major thromboembolic (TE) events, exacerbations and death was studied. Fewer caplacizumab‐treated patients had a major
F. Peyvandi, M. Scully, J. A. Hovinga, P. Knöbl, S. Cataland, K. D. Beuf, F. Callewaert, H. Winter, R. Zeldin   +8 more
semanticscholar   +1 more source

Steroid‐Induced Takotsubo Cardiomyopathy in a Patient With Immune Thrombocytopenic Purpura

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT This case report highlights a temporal relationship between dexamethasone administration and the onset of Takotsubo cardiomyopathy, underscoring the importance of recognizing pharmacologic agents as potential non‐traditional triggers, particularly in patients with underlying cardiovascular disease and no identifiable emotional or physical ...
Qutaiba Qafisheh, Roaa Aljunaidi, Abdalhakim Shubietah, Mohammed AbuBaha, Hossam Salameh, Muath Baniowda, Mohanad Qwaider, Mohammad Alqadi, Imad Hariri   +8 more
wiley   +1 more source