Results 81 to 90 of about 43,474 (218)

Profound Thrombocytopenia and Dyspnea 11 Days After Cardiac Surgery

open access: yes
American Journal of Hematology, Volume 100, Issue 7, Page 1234-1239, July 2025.
Sebastian Vuong   +3 more
wiley   +1 more source

Impact of COVID‐19 Vaccination on Menstrual Irregularities, Bleeding Patterns, and Cycle Duration: A Systematic Review and Meta‐Analysis

open access: yesHealth Science Reports, Volume 8, Issue 6, June 2025.
Abstract Background COVID‐19 vaccination has raised concerns regarding its potential effects on women's reproductive health, particularly menstrual irregularities. This systematic review and meta‐analysis aimed to assess the impact of COVID‐19 vaccination on menstrual disturbances, bleeding patterns, and cycle duration among women of reproductive age ...
Ganesh Bushi   +13 more
wiley   +1 more source

Linking preclinical models to clinical realities: VEGF/VEGFR inhibitors and thrombotic microangiopathy in cancer therapy

open access: yesiMetaOmics, Volume 2, Issue 2, June 2025.
This study investigates the risk of thrombotic microangiopathy (TMA) induced by vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) inhibitors in cancer therapy. Using data from the FDA Adverse Event Reporting System (FAERS), the WHO Global Database for Adverse Drug Reactions (Vigibase), and The Cancer ...
Aimin Jiang   +7 more
wiley   +1 more source

NEONATAL THROMBOCYTOPENIC PURPURA: REPORT OF TWO CASES AND REVIEW OF LITERATURE [PDF]

open access: yesKanem Journal of Medical Sciences, 2018
Introduction: Severe neonatal thrombocytopenia is a hematological emergency that can be due to increased platelet destruction (such as immune-mediated and peripheral platelet consumption) or congenital failure of platelet production.
Abiodun MT, Badejoko B, Oluwafemi RO
doaj  

ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission

open access: yesHaematologica, 2008
Background From 20 to 50% of patients who survive an acute episode of the acquired form of thrombotic thrombocytopenic purpura relapse but clinical and laboratory markers of recurrence are not well established.Design and Methods In 109 patients enrolled ...
Flora Peyvandi   +15 more
doaj   +1 more source

Idiopathic thrombocytopenic purpura in a patient with situs inversus totalis: case report and literature review

open access: yesEinstein (São Paulo), 2020
Situs inversus totalis is a rare recessive autosomal congenital abnormality in which the mediastinal and abdominal organs are in a mirrored position when compared to the usual topography.
Carolina Rodrigues Dal Bo   +4 more
doaj   +2 more sources

Hetrombopag: A promising thrombopoietin receptor agonist for the treatment of primary and secondary immune thrombocytopenia

open access: yesRheumatology &Autoimmunity, Volume 5, Issue 2, Page 101-115, June 2025.
This review seeks to provide a thorough synthesis of the existing literature on the role of thrombopoietin receptor agonists in the treatment of primary and secondary immune thrombocytopenia, with particular emphasis on the compound Hetrombopag. Abstract Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by a platelet count below
Jiaqi Hu   +8 more
wiley   +1 more source

Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain

open access: yesHaematologica, 2011
Background The majority of patients diagnosed with thrombotic thrombocytopenic purpura have autoantibodies directed towards the spacer domain of ADAMTS13.Design and Methods In this study we explored the epitope specificity and immunoglobulin class and ...
Wouter Pos   +6 more
doaj   +1 more source

Degradation of two novel congenital TTP ADAMTS13 mutants by the cell proteasome prevents ADAMTS13 secretion [PDF]

open access: yes, 2016
INTRODUCTION: Over 150 mutations have been identified in the ADAMTS13 gene in patients with congenital thrombotic thrombocytopenic purpura (TTP). The majority of these (86%), lead to reduced (
Garagiola, I   +4 more
core   +1 more source

Living under the sword of Damocles”: a psychological support project for patients with immune thrombocytopenia and their caregivers

open access: yesBleeding, Thrombosis and Vascular Biology
Immune thrombocytopenia (ITP) is an autoimmune disease that causes a drop in platelet count
Giuseppe Auteri   +3 more
doaj   +1 more source

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