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Diagnostic accuracy of the PLASMIC score in patients with suspected thrombotic thrombocytopenic purpura: A systematic review and meta‐analysis

Transfusion, 2020
The PLASMIC score was developed to identify patients with thrombotic microangiopathy who are most likely to have immune thrombotic thrombocytopenic purpura (TTP) and benefit from therapeutic plasma exchange (TPE).
Koosha Paydary   +4 more
semanticscholar   +1 more source

Thrombotic thrombocytopenic purpura

Blood Coagulation & Fibrinolysis, 1992
Thrombotic thrombocytopenic purpura is an uncommon disorder, but it continues to be of considerable interest. The disease mechanisms are unclear and the aetiology is unknown. Perhaps most enigmatic of all, the mode of action of plasma therapy, which successfully induces remission in about two-thirds of cases, is wholly inexplicable. There are currently
Theodore E. Warkentin   +4 more
openaire   +3 more sources

Thrombotic thrombocytopenic purpura

Disease-a-Month, 2014
Moschowitz first described thrombotic thrombocytopenic purpura (TTP) in 1925 in a 16-yearold female who presented with fever, petechiae, and a microangiopathic hemolytic anemia. Autopsy examination at the time revealed hyaline thrombi in the vascular beds of many organs. By 1947, several more cases were described and Singer suggested the term TTP.
Rami Y. Haddad   +3 more
openaire   +3 more sources

Thrombotic Thrombocytopenic Purpura

Archives of Internal Medicine, 1984
Freda Gardner, MD, Senior Assistant Resident, The Jewish Hospital of St Louis: A 42-year-old woman was in good health until four weeks prior to her admission, when she noted that minor trauma caused large ecchymotic lesions. One week prior to admission, she experienced the sudden onset of dysarthria, weakness and paresthesias of her right arm, light ...
Lorence A. Gutterman   +1 more
openaire   +3 more sources

Thrombotic thrombocytopenic purpura

The American Journal of Medicine, 1952
Abstract 1.1. The clinical and pathologic observations of two cases of thrombotic thrombocytopenic purpura are presented. 2.2. This condition is characterized by the clinical triad of (1) hemolytic anemia; (2) thrombocytopenic purpura and (3) mental and neurologic abnormalities which may be bizarre or transient.
Benjamin R. Gendel   +2 more
openaire   +6 more sources

Thrombotic Thrombocytopenic Purpura

New England Journal of Medicine, 2019
Thrombotic Thrombocytopenic Purpura A 35-year-old man presented with a 2-day history of abdominal pain and headache. A peripheral-blood smear showed numerous schistocytes, and a diagnosis of thrombotic thrombocytopenic purpura was made.
Shruti Bhandari, Rohit Kumar
openaire   +2 more sources

Efficacy and Safety of Rituximab in Connective Tissue Disease‐Associated Thrombotic Thrombocytopenic Purpura/Thrombotic Microangiopathy

International Journal of Rheumatic Diseases
This study examined the efficacy and safety of Rituximab (RTX) treatment in connective tissue disease (CTD)‐associated thrombocytopenic purpura (TTP) and thrombotic microangiopathy (TMA), using historical controls as comparators.
N. Ohkubo   +7 more
semanticscholar   +1 more source

Thrombotic Thrombocytopenic Purpura

JAMA: The Journal of the American Medical Association, 1991
CASE PRESENTATION —Charles T. Bingham III, MD A 27-YEAR-OLD man was transferred to The Johns Hopkins Hospital for evaluation of delirium. Five days prior to admission he had presented to another hospital with hematemesis and syncope. Esophagogastroduodenoscopy revealed the presence of a 0.5-cm gastric ulcer.
openaire   +3 more sources

An update on pathogenesis and diagnosis of thrombotic thrombocytopenic purpura

Expert Review of Hematology, 2019
Introduction: Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, consumption thrombocytopenia, and organ injury. TTP pathophysiology is based on a severe
B. Joly, P. Coppo, A. Veyradier
semanticscholar   +1 more source

Thrombotic thrombocytopenic purpura

The Journal of Maternal-Fetal & Neonatal Medicine, 2012
A 34-year old primipara was admitted to hospital with dichorionic-diamniotic twins in 26+3 weeks of gestation. In suspicion of HELLP-syndrome, caesarean section was performed at 27+4 weeks of gestation, because of platelet count was reduced to 44000/µl. A re-laparotomy had to be performed because of intra-abdominal bleedings.
Anne-Sybil Gast   +3 more
openaire   +3 more sources

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