Results 11 to 20 of about 46,143 (249)

Thrombotic thrombocytopenic purpura [PDF]

open access: yesNature Reviews Disease Primers, 2017
Thrombotic thrombocytopenic purpura (TTP; also known as Moschcowitz disease) is characterized by the concomitant occurrence of often severe thrombocytopenia, microangiopathic haemolytic anaemia and a variable degree of ischaemic organ damage, particularly affecting the brain, heart and kidneys.
Kremer Hovinga, Johanna A.   +5 more
semanticscholar   +8 more sources

Hereditary thrombotic thrombocytopenic purpura

open access: yesHaematologica, 2019
The first description of thrombotic thrombocytopenic purpura (TTP) by Moschowitz was published nearly 100 years ago.[1][1] This was likely to have been an immune-mediated TTP episode and the author described multi organs affected with worsening, untreated disease.
Marie Scully
doaj   +9 more sources

Vaccination and Thrombotic Thrombocytopenic Purpura

open access: yesTurkish Journal of Hematology, 2020
In the adult age group, vaccines did not contribute to the development of immune thrombocytopenia (ITP), but an increase was reported in diphtheria-tetanus-pertussis-poliomyelitis vaccines without statistical significance [2].
I. Yavaşoğlu
openaire   +5 more sources

Thrombotic Thrombocytopenic Purpura

open access: yesJournal of Associated Medical Sciences, 2015
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Nuchanat Nonsee, Prasit Chanarat
doaj   +4 more sources

Thrombotic thrombocytopenic purpura [PDF]

open access: yesmemo - Magazine of European Medical Oncology, 2018
Thrombotic thrombocytopenic purpura (TTP) is a clearly defined entity of the thrombotic microangiopathies (TMA), a heterogeneous group of disorders characterized by microangiopathic hemolytic anemia with red cell fragmentation, thrombocytopenia and organ dysfunction due to disturbed microcirculation.
Yaakov Beilin, Joshua Hamburger
openaire   +5 more sources

A British Society for Haematology Guideline: Diagnosis and management of thrombotic thrombocytopenic purpura and thrombotic microangiopathies

open access: yesBritish Journal of Haematology, 2023
The objective of this guideline is to provide healthcare professionals with clear, up‐to‐date and practical guidance on the management of thrombotic thrombocytopenic purpura (TTP) and related thrombotic microangiopathies (TMAs), including complement ...
M. Scully   +12 more
semanticscholar   +1 more source

Thrombotic Thrombocytopenic Purpura: Pathophysiology, Diagnosis, and Management

open access: yesJournal of Clinical Medicine, 2021
Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and ischemic end organ injury due to microvascular platelet-rich thrombi.
S. Sukumar, B. Lämmle, S. Cataland
semanticscholar   +1 more source

Thrombotic Thrombocytopenic Purpura After Ad6.COV2.S Vaccination

open access: yesCureus, 2022
Thrombotic thrombocytopenic purpura (TTP) is caused by the deficiency of ADAMTS13, a von Willebrand factor cleaving protease, which results in thrombotic microangiopathy.
S. Ramanan   +5 more
semanticscholar   +1 more source

Recombinant ADAMTS13 for Hereditary Thrombotic Thrombocytopenic Purpura.

open access: yesNew England Journal of Medicine, 2022
A 27-year-old patient with a history of severe obstetrical complications and arterial thrombosis received a diagnosis of hereditary thrombotic thrombocytopenic purpura (TTP) due to severe ADAMTS13 deficiency when she presented with an acute episode in ...
L. Asmis   +9 more
semanticscholar   +1 more source

Efficacy and Safety of Rituximab in Connective Tissue Disease-Associated Thrombotic Thrombocytopenic Purpura/Thrombotic Microangiopathy. [PDF]

open access: yesInt J Rheum Dis
This study examined the efficacy and safety of Rituximab (RTX) treatment in connective tissue disease (CTD)‐associated thrombocytopenic purpura (TTP) and thrombotic microangiopathy (TMA), using historical controls as comparators.
Ohkubo N   +7 more
europepmc   +2 more sources

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