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Thrombotic thrombocytopenic purpura [PDF]

memo - Magazine of European Medical Oncology, 2018
Thrombotic thrombocytopenic purpura (TTP) is a clearly defined entity of the thrombotic microangiopathies (TMA), a heterogeneous group of disorders characterized by microangiopathic hemolytic anemia with red cell fragmentation, thrombocytopenia and organ dysfunction due to disturbed microcirculation.
Yaakov Beilin, Joshua Hamburger
openaire   +5 more sources

A British Society for Haematology Guideline: Diagnosis and management of thrombotic thrombocytopenic purpura and thrombotic microangiopathies

British Journal of Haematology, 2023
The objective of this guideline is to provide healthcare professionals with clear, up‐to‐date and practical guidance on the management of thrombotic thrombocytopenic purpura (TTP) and related thrombotic microangiopathies (TMAs), including complement ...
M. Scully, R. Rayment, A. Clark, J. Westwood, T. Cranfield, R. Gooding, C. Bagot, A. Taylor, V. Sankar, D. Gale, T. Dutt, J. McIntyre, W. Lester   +12 more
semanticscholar   +1 more source

Case Report: Rabies Vaccine-Induced Thrombotic Thrombocytopenic Purpura in a Patient With Systemic Lupus Erythematosus

Frontiers in Immunology, 2022
For patients with autoimmune diseases, vaccination is controversial. The use of vaccination in patients with autoimmune diseases is controversial. There are many reports of secondary thrombotic thrombocytopenic purpura cases after various vaccinations ...
Yanming Cui, Jianbo Wei, Xiang Peng
doaj   +1 more source

Concurrence of immune thrombocytopenic purpura and thrombotic thrombocytopenic purpura: a case report and review of the literature

Journal of Medical Case Reports, 2023
Background Immune thrombocytopenic purpura and thrombotic thrombocytopenic purpura are both causes of thrombocytopenia. Recognizing thrombotic thrombocytopenic purpura is crucial for subsequent treatment and prognosis.
Hung-Chen Lin, Jinxiang Huang, Jing Huang, Li-Jun Zhang, Xiao-Wu Yin, Jian-Cheng Yang, Xiao-Yan Huang   +6 more
doaj   +1 more source

Thrombotic Thrombocytopenic Purpura: Pathophysiology, Diagnosis, and Management

Journal of Clinical Medicine, 2021
Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and ischemic end organ injury due to microvascular platelet-rich thrombi.
S. Sukumar, B. Lämmle, S. Cataland
semanticscholar   +1 more source

Thrombotic Thrombocytopenic Purpura After Ad6.COV2.S Vaccination

Cureus, 2022
Thrombotic thrombocytopenic purpura (TTP) is caused by the deficiency of ADAMTS13, a von Willebrand factor cleaving protease, which results in thrombotic microangiopathy.
S. Ramanan, H. Singh, P. Menon, Parth M Patel, VR Parmar, Devin Malik   +5 more
semanticscholar   +1 more source

Recombinant ADAMTS13 for Hereditary Thrombotic Thrombocytopenic Purpura.

New England Journal of Medicine, 2022
A 27-year-old patient with a history of severe obstetrical complications and arterial thrombosis received a diagnosis of hereditary thrombotic thrombocytopenic purpura (TTP) due to severe ADAMTS13 deficiency when she presented with an acute episode in ...
L. Asmis, A. Serra, A. Krafft, A. Licht, E. Leisinger, J. Henschkowski-Serra, M. Ganter, S. Hauptmann, M. Tinguely, J. K. Kremer Hovinga   +9 more
semanticscholar   +1 more source

Coexistence of thrombotic thrombocytopenic purpura and immune thrombocytopenic purpura in an Asian woman: a case report

Journal of International Medical Research, 2022
A 33-year-old Chinese woman with a history of immune thrombocytopenic purpura presented with heavy menstrual bleeding. She was found to have thrombocytopenia, plasma ADAMTS13 activity of 0%, and positivity for the plasma ADAMTS13 inhibitor.
Hangping Ge, Zhan Shi, Zhiyin Zheng, Qiuping Zhu, Lili Hong, Yu Zhang, Jianping Shen, Shu Deng   +7 more
doaj   +1 more source

Caplacizumab prevents refractoriness and mortality in acquired thrombotic thrombocytopenic purpura: integrated analysis.

Blood Advances, 2021
The efficacy and safety of caplacizumab in individuals with acquired thrombotic thrombocytopenic purpura (aTTP) have been established in the phase 2 TITAN and phase 3 HERCULES trials. Integrated analysis of data from both trials was conducted to increase
F. Peyvandi, S. Cataland, M. Scully, P. Coppo, P. Knoebl, J. K. Kremer Hovinga, A. Metjian, J. de la Rubia, K. Pavenski, Jessica Minkue Mi Edou, H. de Winter, F. Callewaert   +11 more
semanticscholar   +1 more source

Thrombotic thrombocytopenic purpura: a new menace after COVID bnt162b2 vaccine

International journal of hematology, 2021
Thrombotic thrombocytopenic purpura (TTP) is a known menace in hematology and is quite rare in practice with known triggers. Lately, in the COVID-19 pandemic, hematology has seen a new pathology amongst which TTP associated with COVID-19 messenger RNA ...
S. H. Waqar, A. Khan, S. Memon
semanticscholar   +1 more source