Results 61 to 70 of about 25,607 (238)

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

open access: yesAdvanced Science, EarlyView.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao   +12 more
wiley   +1 more source

Interception Domain Approach to Orbital Multi-Player “Encirclement-Capture” Games: Theoretical Foundations and Solutions

open access: yesAerospace
In recent years, with the development of micro-satellite clusters and large-scale satellite constellations, the likelihood of multiple spacecraft engaging in orbital pursuit–evasion games has increased.
Xingchen Li   +4 more
doaj   +1 more source

Neutrophil‐Mimetic Nanoscavengers Target the Inflammatory Microenvironment to Eliminate NETs/ROS and Immunomodulate cGAS‐STING Signaling in Septic AKI

open access: yesAdvanced Science, EarlyView.
Sepsis‐associated acute kidney injury is driven by oxidative stress, NETs overproduction, and dysregulated innate immunity. Here, we develop neutrophil‐mimetic nanoscavengers that integrate ROS‐scavenging Mn3O4 nanozymes with DNase‐1‐mediated NETs degradation to suppress cGAS‐STING signaling, reprogram macrophage polarization, and effectively alleviate
Zening Zhang   +9 more
wiley   +1 more source

Multi-Agent Pursuit-Evasion Game Based on Organizational Architecture

open access: yesJournal of Computing and Information Technology, 2019
Multi-agent coordination mechanisms are frequently used in pursuit-evasion games with the aim of enabling the coalitions of the pursuers and unifying their individual skills to deal with the complex tasks encountered.
Mohammed El Habib Souidi   +3 more
doaj   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

The Role of Visibility in Pursuit/Evasion Games

open access: yesRobotics, 2014
The cops-and-robber (CR) game has been used in mobile robotics as a discretized model (played on a graph G) of pursuit/evasion problems. The “classic” CR version is a perfect information game: the cops’ (pursuer’s) location is always known to the robber (
Athanasios Kehagias   +2 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Computer vision and pursuit–evasion game theoretical controls for ground robots

open access: yesAdvances in Mechanical Engineering, 2019
A hardware-in-loop control framework with robot dynamic models, pursuit–evasion game models, sensor and information solutions, and entity tracking algorithms is designed and developed to demonstrate discrete-time robotic pursuit–evasion games for real ...
Dan Shen   +4 more
doaj   +1 more source

PURSUIT-EVASION DIFFERENTIAL GAMES WITH THE GRÖNWALL TYPE CONSTRAINTS ON CONTROLS

open access: yesUral Mathematical Journal, 2020
A simple pursuit-evasion differential game of one pursuer and one evader is studied. The players' controls are subject to differential constraints in the form of the integral Grönwall inequality.
Bahrom T. Samatov   +2 more
doaj   +1 more source

Two-Dimensional Pursuit-Evasion in a Compact Domain with Piecewise Analytic Boundary

open access: yes, 2015
In a pursuit-evasion game, a team of pursuers attempt to capture an evader. The players alternate turns, move with equal speed, and have full information about the state of the game.
Beveridge, Andrew, Cai, Yiqing
core  

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