Results 51 to 60 of about 1,501 (112)

Abstract

, 2022
Research and Practice in Thrombosis and Haemostasis, Volume 6, Issue S1, October 2022.
wiley   +1 more source

Obtaining a Recombinant Nucleoprotein of the Puumala Virus for Serological Diagnostics of Hemorrhagic Fever with Renal Syndrome

Проблемы особо опасных инфекций
Puumala virus (Orthohantavirus puumalaense) is one of the causative agents of hemorrhagic fever with renal syndrome (HFRS), which is widespread in the Russian Federation (RF): more than 6 thousand cases of HFRS infection are registered annually, over the
A. E. Tishin, S. A. P’yankov, E. Yu. Prudnikova, I. R. Imatdinov   +3 more
doaj   +1 more source

Unraveling the Mechanistic Links Between Species Diversity and Infection Risk From Zoonotic Pathogens With Direct Transmission Among Reservoir Hosts: Rodent‐Orthohantavirus Systems as Models

Ecology and Evolution, Volume 15, Issue 6, June 2025.
In this review, we synthesize mechanistic evidence for diversity‐disease patterns in rodent‐orthohantavirus systems in the Americas, models of directly transmitted disease systems. We found that host regulation has been examined the most while other mechanisms have received less attention. Based on our findings, we propose that for a negative diversity‐
Andreas Eleftheriou, Angela D. Luis
wiley   +1 more source

Hantavirus in rodents in the United States: Temporal and spatial trends and report of new hosts

Ecosphere, Volume 16, Issue 3, March 2025.
Abstract In North America, the rodent‐borne hantavirus pulmonary syndrome is predominantly caused by the Sin Nombre virus, typically associated with the deer mouse Peromyscus maniculatus. Utilizing data from the National Ecological Observatory Network (NEON) hantavirus program, we assessed factors that may influence the spatial and temporal ...
Francisca Astorga, Abdelghafar Alkishe, Paanwaris Paansri, Gabriel Mantilla, Luis E. Escobar   +4 more
wiley   +1 more source

Cross-binding antibodies capable of neutralising diverse hantaviruses are produced in response to Puumala virus infectionResearch in context

EBioMedicine
Summary: Background: Orthohantaviruses (hantaviruses) are emerging rodent-borne pathogens that can cause severe human disease. They are present on multiple continents and are responsible for thousands of human cases per year.
Jordan J. Clark, Stefan Hatzl, Kirill Vasilev, Robert Andreata-Santos, Jeremy S. Yong, Eva Mittler, Ezgi Kasikci, Kartik Chandran, Viviana Simon, Robert Krause, Florian Krammer   +10 more
doaj   +1 more source

Seroprevalence of Hantavirus in Forestry Workers, Northern France, 2019–2020

Viruses, 2023
We aimed to estimate the seroprevalence of Puumala orthohantavirus (PUUV) among forestry workers in northern France, and to explore sociodemographic risk factors.
Catarina Krug, Emma Rigaud, Dieyenaba Siby-Diakite, Laetitia Bénézet, Pavlos Papadopoulos, Henriette de Valk, Gaëtan Deffontaines, Alexandra Septfons, Jean-Marc Reynes   +8 more
doaj   +1 more source

Hantaan virus glycoprotein Gc induces NEDD4‐dependent PTEN ubiquitination and degradation to escape the restriction of autophagosomes and facilitate viral propagation

The FASEB Journal, Volume 39, Issue 1, 15 January 2025.
The proposed model of HTNV induced PTEN degradation and PTEN‐regulated autophagy in progeny virus production: In HTNV‐infected HK‐2 cells, the viral Gc glycoprotein specifically promotes NEDD4 mediated ubiquitination and degradation of PTEN. Disruption of PTEN expression prevents autophagosome formation and increases HTNV production, whereas ...
Shuang Lu, Shuliang Chen, Yuqing Zhang, Xiaoli Mou, Mingyang Li, Shaowei Zhu, Xingyuan Chen, Tomas M. Strandin, Yale Jiang, Zhoufu Xiang, Yuanyuan Liu, Hairong Xiong, Deyin Guo, Liangjun Chen, Yirong Li, Wei Hou, Fan Luo   +16 more
wiley   +1 more source

Puumala Hantavirus Genotypes in Humans, France, 2012–2016

Emerging Infectious Diseases, 2019
The analysis of the nucleoprotein gene of 77 Puumala hantavirus strains detected in human samples in France during 2012–2016 showed that all belonged to the Central European lineage.
Jean-Marc Reynes, Damien Carli, Damien Thomas, Guillaume Castel   +3 more
doaj   +1 more source

Unveiling the impacts of land use on the phylogeography of zoonotic New World Hantaviruses

Ecography, Volume 2024, Issue 10, October 2024.
Billions of genomic sequences and records of species occurrence are available in public repositories (e.g. National Center for Biotechnology Information, NCBI and the Global Biodiversity Information Facility, GBIF). By implementing analytical tools from different scientific disciplines, data mining these databases can aid in the global surveillance of ...
Gabriel E. García‐Peña, André V. Rubio   +1 more
wiley   +1 more source

Nephropathia Epidemica Caused by Puumala Virus in Bank Voles, Scania, Southern Sweden

Emerging Infectious Diseases
In 2018, a local case of nephropathia epidemica was reported in Scania, southern Sweden, more than 500 km south of the previously known presence of human hantavirus infections in Sweden. Another case emerged in the same area in 2020.
Jiaxin Ling, Elin Economou Lundeberg, Anishia Wasberg, Inês R. Faria, Sanja Vucicevic, Bo Settergren, Åke Lundkvist   +6 more
doaj   +1 more source