Results 51 to 60 of about 2,318 (177)

Hormonal Defects Are Common during Puumala Hantavirus Infection and Associate with Disease Severity and Biomarkers of Altered Haemostasis

Viruses, 2021
Central and peripheral hormone deficiencies have been documented during and after acute hantavirus infection. Thrombocytopenia and coagulation abnormalities are common findings in haemorrhagic fever with renal syndrome (HFRS).
Marlene Tarvainen, Satu Mäkelä, Outi Laine, Ilkka Pörsti, Sari Risku, Onni Niemelä, Jukka Mustonen, Pia Jaatinen   +7 more
doaj   +1 more source

Phylogeographic Diversity of Pathogenic and Non-Pathogenic Hantaviruses in Slovenia

Viruses, 2013
Slovenia is a very diverse country from a natural geography point of view, with many different habitats within a relatively small area, in addition to major geological and climatic differences.
Miša Korva, Nataša Knap, Katarina Resman Rus, Luka Fajs, Gašper Grubelnik, Matejka Bremec, Tea Knapič, Tomi Trilar, Tatjana Avšič Županc   +8 more
doaj   +1 more source

Unraveling the Mechanistic Links Between Species Diversity and Infection Risk From Zoonotic Pathogens With Direct Transmission Among Reservoir Hosts: Rodent‐Orthohantavirus Systems as Models

Ecology and Evolution, Volume 15, Issue 6, June 2025.
In this review, we synthesize mechanistic evidence for diversity‐disease patterns in rodent‐orthohantavirus systems in the Americas, models of directly transmitted disease systems. We found that host regulation has been examined the most while other mechanisms have received less attention. Based on our findings, we propose that for a negative diversity‐
Andreas Eleftheriou, Angela D. Luis
wiley   +1 more source

Risk factors and potential preventive measures for nephropatia epidemica in Sweden 2011–2012: a case–control study [PDF]

Infection Ecology & Epidemiology, 2015
Introduction: Nephropatia epidemica (NE), a relatively mild form of hemorrhagic fever with renal syndrome caused by the Puumala virus (PUUV), is endemic in northern Sweden. We aim to study the risk factors associated with NE in this region.
Alin Gherasim, Marika Hjertqvist, Åke Lundkvist, Sharon Kühlmann-Berenzon, Jenny Verner Carlson, Stephan Stenmark, Mikael Widerström, Anders Österlund, Hans Boman, Clas Ahlm, Anders Wallensten   +10 more
doaj   +1 more source

Hantavirus in rodents in the United States: Temporal and spatial trends and report of new hosts

Ecosphere, Volume 16, Issue 3, March 2025.
Abstract In North America, the rodent‐borne hantavirus pulmonary syndrome is predominantly caused by the Sin Nombre virus, typically associated with the deer mouse Peromyscus maniculatus. Utilizing data from the National Ecological Observatory Network (NEON) hantavirus program, we assessed factors that may influence the spatial and temporal ...
Francisca Astorga, Abdelghafar Alkishe, Paanwaris Paansri, Gabriel Mantilla, Luis E. Escobar   +4 more
wiley   +1 more source

Phylogeography of Puumala orthohantavirus in Europe

Viruses, 2019
Puumala virus is an RNA virus hosted by the bank vole (Myodes glareolus) and is today present in most European countries. Whilst it is generally accepted that hantaviruses have been tightly co-evolving with their hosts, Puumala virus (PUUV) evolutionary ...
Guillaume Castel, François Chevenet, Maria Razzauti, Séverine Murri, Philippe Marianneau, Jean-François Cosson, Noël Tordo, Alexander Plyusnin   +7 more
doaj   +1 more source

Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components

WIREs RNA, Volume 16, Issue 2, March/April 2025.
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus, Eliana Dukhno, Rupali Kapoor, Piotr Gerlach   +3 more
wiley   +1 more source

Natural Focal Viral Fevers in the South of the European Part of Russia. Hemorrhagic Fever with Renal syndrome

Проблемы особо опасных инфекций, 2020
Objective of the study was to determine the modem epizootic and epidemic peculiarities of hemorrhagic fever with renal syndrome in the south of the European part of Russia. Materials and methods.
O. V. Maletskaya, T. V. Taran, D. A. Prislegina, A. E. Platonov, V. M. Dubyansky, A. S. Volynkina, N. F. Vasilenko, Yu. N. Tokhov, N. V. Tsapko   +8 more
doaj   +1 more source

Determinants of the geographic distribution of Puumala virus and Lyme borreliosis infections in Belgium [PDF]

International Journal of Health Geographics, 2007
Vector-borne and zoonotic diseases generally display clear spatial patterns due to different space-dependent factors. Land cover and land use influence disease transmission by controlling both the spatial distribution of vectors or hosts, and the probability of contact with susceptible human populations.
Catherine Linard, Pénélope Lamarque, Paul Heyman, G Ducoffre, V. Luyasu, Katrien Tersago, Sophie Vanwambeke, Éric F. Lambin   +7 more
openalex   +9 more sources

Hantaan virus glycoprotein Gc induces NEDD4‐dependent PTEN ubiquitination and degradation to escape the restriction of autophagosomes and facilitate viral propagation

The FASEB Journal, Volume 39, Issue 1, 15 January 2025.
The proposed model of HTNV induced PTEN degradation and PTEN‐regulated autophagy in progeny virus production: In HTNV‐infected HK‐2 cells, the viral Gc glycoprotein specifically promotes NEDD4 mediated ubiquitination and degradation of PTEN. Disruption of PTEN expression prevents autophagosome formation and increases HTNV production, whereas ...
Shuang Lu, Shuliang Chen, Yuqing Zhang, Xiaoli Mou, Mingyang Li, Shaowei Zhu, Xingyuan Chen, Tomas M. Strandin, Yale Jiang, Zhoufu Xiang, Yuanyuan Liu, Hairong Xiong, Deyin Guo, Liangjun Chen, Yirong Li, Wei Hou, Fan Luo   +16 more
wiley   +1 more source