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Puumala virus (Orthohantavirus puumalaense) is one of the causative agents of hemorrhagic fever with renal syndrome (HFRS), which is widespread in the Russian Federation (RF): more than 6 thousand cases of HFRS infection are registered annually, over the
A. E. Tishin +3 more
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Hantavirus Pulmonary Syndrome in Traveler Returning from Nepal to Spain
Most human hantavirus infections occur in Asia, but some cases have been described in Europe in travelers returning from Asia. We describe a case of hantavirus pulmonary syndrome in a previously healthy traveler occurring shortly after he returned to ...
Elena Sulleiro +13 more
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Zoonotic Hantaviridae with Global Public Health Significance
Hantaviridae currently encompasses seven genera and 53 species. Multiple hantaviruses such as Hantaan virus, Seoul virus, Dobrava-Belgrade virus, Puumala virus, Andes virus, and Sin Nombre virus are highly pathogenic to humans.
Rui-Xu Chen +8 more
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Phylogeographic Diversity of Pathogenic and Non-Pathogenic Hantaviruses in Slovenia
Slovenia is a very diverse country from a natural geography point of view, with many different habitats within a relatively small area, in addition to major geological and climatic differences.
Miša Korva +8 more
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In this review, we synthesize mechanistic evidence for diversity‐disease patterns in rodent‐orthohantavirus systems in the Americas, models of directly transmitted disease systems. We found that host regulation has been examined the most while other mechanisms have received less attention. Based on our findings, we propose that for a negative diversity‐
Andreas Eleftheriou, Angela D. Luis
wiley +1 more source
Phylogeography of Puumala orthohantavirus in Europe
Puumala virus is an RNA virus hosted by the bank vole (Myodes glareolus) and is today present in most European countries. Whilst it is generally accepted that hantaviruses have been tightly co-evolving with their hosts, Puumala virus (PUUV) evolutionary ...
Guillaume Castel +7 more
doaj +1 more source
Susceptibility of human cells to Puumala virus infection
Nephropathia epidemica involves several organs including kidney, lung, liver and brain. To investigate the susceptibility of putative target cells to the agent responsible, Puumala virus, we screened established human cell lines of lung (WI-38, A-427, CCD-11Lu), kidney (A-704), liver (Hep G2), pharynx (Detroit 562), submaxillary gland (A-253) and ...
M, Temonen +5 more
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Hantavirus in rodents in the United States: Temporal and spatial trends and report of new hosts
Abstract In North America, the rodent‐borne hantavirus pulmonary syndrome is predominantly caused by the Sin Nombre virus, typically associated with the deer mouse Peromyscus maniculatus. Utilizing data from the National Ecological Observatory Network (NEON) hantavirus program, we assessed factors that may influence the spatial and temporal ...
Francisca Astorga +4 more
wiley +1 more source
Global dynamics of a stage-structured hantavirus infection model with seasonality
In this paper, we study a time-periodic model, which incorporates seasonality and host stage-structure. This model describes the propagation of Puumala hantavirus within the bank vole population of Clethrionomys glareolus.
Junli Liu, Tailei Zhang
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Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus +3 more
wiley +1 more source

