Results 81 to 90 of about 15,947 (175)

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source

Prevalence of Panton-Valentine Leukocidin (PVL) and Antimicrobial Resistance in Community-Acquired Clinical Staphylococcus aureus in an Urban Gambian Hospital: A 11-Year Period Retrospective Pilot Study

Frontiers in Cellular and Infection Microbiology, 2019
Background:Staphylococcus aureus is a major human pathogen. Panton-Valentine leukocidin (PVL) is a virulence factor produced by some strains that causes leukocyte lysis and tissue necrosis. PVL-associated S.
Saffiatou Darboe, Sarah Dobreniecki, Sheikh Jarju, Mamadou Jallow, Nuredin Ibrahim Mohammed, Miriam Wathuo, Buntung Ceesay, Sam Tweed, Robindra Basu Roy, Uduak Okomo, Brenda Kwambana-Adams, Martin Antonio, Richard S. Bradbury, Thushan I. de Silva, Karen Forrest, Anna Roca, Bolarinde Joseph Lawal, Davis Nwakanma, Ousman Secka   +18 more
doaj   +1 more source

Commissural Misalignment Following Valve‐in‐Valve Transcatheter Aortic Valve Implantation

Catheterization and Cardiovascular Interventions, Volume 107, Issue 4, Page 1215-1224, March 1, 2026.
ABSTRACT Background Data on commissural misalignment (CMA) during valve‐in‐valve transcatheter aortic valve implantation (ViV‐TAVI) for valve failure after surgical aortic valve replacement (SAVR) is scarce. Aims To study the impact of CMA on clinical and hemodynamic outcomes following ViV‐TAVI for failed SAVR.
Matthias Raschpichler, Johannes Rotta Detto Loria, Vivek Patel, Thilo Noack, Karoline Nüsser, Oliver Dumpies, Dhairya Patel, Takashi Nagasaka, Prateek Madaan, Aakriti Gupta, Holger Thiele, Michael A. Borger, Raj Makkar, Mohamed Abdel‐Wahab   +13 more
wiley   +1 more source

Panton-Valentine leukocidin is not the primary determinant of outcome for Staphylococcus aureus skin infections: evaluation from the CANVAS studies.

PLoS ONE, 2012
The impact of Panton-Valentine leukocidin (PVL) on the severity of complicated skin and skin structure infections (cSSSI) caused by Staphylococcus aureus is controversial.
Amy Tong, Steven Y C Tong, Yurong Zhang, Supaporn Lamlertthon, Batu K Sharma-Kuinkel, Thomas Rude, Sun Hee Ahn, Felicia Ruffin, Lily Llorens, Ganesh Tamarana, Donald Biek, Ian Critchley, Vance G Fowler   +12 more
doaj   +1 more source

Loss of the Y Chromosome in Oral Potentially Premalignant Disorders Predicts Malignant Progression: An Integrative Cross‐Species Multi‐Cohort Bioinformatic Study

Head &Neck, Volume 48, Issue 3, Page 782-793, March 2026.
ABSTRACT Background The loss of the Y chromosome (LOY) and the extreme down‐regulation of Y chromosome gene expression (EDY) are frequently observed in oral squamous cell carcinoma (OSCC). However, their roles in oral potentially malignant disorders (OPMDs) are unclear.
Rui Han, Jos B. Poell, Cristina Conde‐Lopez, Tuula Salo, Ina Kurth, Ruud H. Brakenhoff, Jochen Hess   +6 more
wiley   +1 more source

Multidrug‐Resistant Pathogen Clonal Spread in Nigeria: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aim The rapid dissemination of multidrug‐resistant (MDR) bacterial clones poses a global health threat and limits treatment options. Understanding the dynamics of bacterial clones in Nigeria is essential for developing effective control strategies. This systematic review aimed to track MDR pathogen clones in Nigeria. Methods The
Emmanuel N. Ugbo, Felicitas N. Afiukwa, Mustofa H. Effendi, Samuel Darkwah, Alex Odoom, Eric S. Donkor   +5 more
wiley   +1 more source

Heterogeneous patterns of axonal injury in periventricular leukomalacia (PVL)

Journal of Neuropathology and Experimental Neurology, 2007
PVL, the major disorder underlying neurodevelopmental disabilities in premature infants, is associated with reduced white matter (WM) volume, impaired myelination, and ventriculomegaly. We hypothesize that these neuropathologic consequences are due, in part, to axonal injury in the damaged (gliotic) cerebral WM surrounding and extending beyond the foci
Robin L Haynes, Saraid S Billiard, Natalia S Borenstein, Joseph J Volpe, Hannah C Kinney   +4 more
openaire   +1 more source

Retinoids and proliferative verrucous leukoplakia (PVL). A preliminary study

Medicina Oral Patología Oral y Cirugia Bucal, 2009
A study is made of the efficacy and adverse effects of retinoid therapy applied to the white lesions of proliferative verrucous leukoplakia (PVL).The results of retinoid therapy were evaluated in 17 patients diagnosed with PVL. Topical retinoids were used in 5 patients, in the form of two daily applications of 0.1% 13-cis-retinoic acid in orabase for ...
Poveda Roda, Rafael, Bagán Sebastián, José Vicente, Jiménez Soriano, Yolanda, Díaz Fernández, José María, Gavaldá Esteve, Carmen   +4 more
openaire   +3 more sources

Brain Injury and Neurodevelopmental Outcome in Survivors After Spontaneous Single Fetal Demise in Monochorionic Twins: A Systematic Review and Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 4, Page 570-578, March 2026.
ABSTRACT Background Monochorionic (MC) twins are at risk of acute exsanguination after single fetal demise (sFD) due to their shared placental circulation, which may result in sequelae for survivors. Objectives To evaluate the prevalence of ante‐ and postnatal brain injury and long‐term neurodevelopmental impairment (NDI) in co‐twins after sFD ...
Mathies Rondagh, Lotte C. M. Zwinkels, Jeanine M. M. van Klink, Linda S. de Vries, Sylke J. Steggerda, Femke Slaghekke, E. J. T. (Joanne) Verweij, Monique C. Haak, Sophie G. Groene, Enrico Lopriore   +9 more
wiley   +1 more source

Community-acquired PVL+ MRSA in Ireland: a preliminary report

Weekly releases (1997–2007), 2005
Cases of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infection were recently detected for the first time in ...
Angela, Rossney, Pamela, Morgan, Brian, O'Connell   +2 more
openaire   +2 more sources