Results 131 to 140 of about 35,871 (258)
Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise +3 more
wiley +1 more source
MLMP: A Methylation‐Associated lncRNA‐mRNA Prognostic Signature for Endometrial Carcinoma
ABSTRACT Background Endometrial carcinoma (EC) is one of the most common gynecological malignancies. Aberrant DNA methylation (DNAm) is an important epigenetic alteration involved in cancer progression. Long non‐coding RNAs (LncRNAs) play critical roles in gene regulation and pathological processes.
Hong Kou +10 more
wiley +1 more source
Targeting PVR (CD155) and its receptors in anti-tumor therapy
Poliovirus receptor (PVR, CD155) has recently been gaining scientific interest as a therapeutic target in the field of tumor immunology due to its prominent endogenous and immune functions.
Pini Tsukerman +11 more
core +1 more source
Right ventricular dysfunction affects 19%–33% of patients With heart failure With preserved ejection fraction and is associated With exercise intolerance, hospitalization, and mortality. Assessing right ventricular function and its coupling with the pulmonary circulation may improve risk stratification and support management tailored to distinct ...
Amarelle Chamoun +13 more
wiley +1 more source
ABSTRACT Steel Concentrically Braced Frames (CBFs) are widely used in seismic regions, with chevron and split‐X configurations commonly adopted for their structural efficiency and architectural flexibility. Although extensive research has been carried out on these systems, the effectiveness of the formulations available in the literature for estimating
Melina Bosco, Pier Paolo Rossi
wiley +1 more source
ABSTRACT Introduction Pelvic organ prolapse can cause urinary tract obstruction, leading to hydronephrosis, pyelonephritis, and in rare cases, renal abscess. Case Presentation We report two elderly women with advanced pelvic organ prolapse who developed renal abscesses.
Hiroki Sai +4 more
wiley +1 more source
“What Medical Management Should Be First Line for Bladder Storage Symptoms in NLUTD”—Pro Botox
ABSTRACT Objectives Neurogenic lower urinary tract dysfunction (NLUTD) severely impairs patient quality of life (QoL). While oral medications are often first‐line treatments, their high failure rates and side effects limit their effectiveness. Thus, we argue for the use of intravesical botulinum toxin A (BoNT‐A) injections as a first‐line alternative ...
Vada Furlan +2 more
wiley +1 more source
Proliferative vitreoretinopathy
Background: Proliferative vitreoretinopathy (PVR) is a disease characterized by formation of membranes on both surfaces of the retina and vitreous base. PVR is a wound healing response which is inadequate and uncontrolled in the eye. Identifying the risk
Mojca Globočnik-Petrovič +1 more
doaj
ABSTRACT Aims Neurogenic lower urinary tract dysfunction (NLUTD) describes a wide range of symptoms depending on neurologic diagnosis and the resulting bladder and sphincter dysfunction. This narrative review is designed to address the question regarding which NLUTD population benefits most from pelvic floor therapy and behavioral interventions, and ...
Sara M. Lenherr
wiley +1 more source

