Results 1 to 10 of about 4,197,466 (259)

Pulmonary and systemic hemodynamics are associated with myocardial injury in the acute respiratory distress syndrome

open access: yesPulmonary Circulation, 2020
Background Whether right and left heart hemodynamics are associated with myocardial injury in the acute respiratory distress syndrome (ARDS) is not known.
Thomas S Metkus   +5 more
doaj   +1 more source

Evaluation of microvasculopathy using dual-energy computed tomography in patients with chronic thromboembolic pulmonary hypertension

open access: yesPulmonary Circulation, 2021
The existence of microvasculopathy in patients with chronic thromboembolic pulmonary hypertension has been suggested. Recently, dual-energy computed tomography has been used to produce a sensitive iodine distribution map in lung fields to indicate ...
Hiroyuki Onishi   +10 more
doaj   +1 more source

Influence of advanced pulmonary vascular remodeling on accuracy of echocardiographic parameters of left ventricular filling pressure

open access: yesPulmonary Circulation, 2021
Evaluation of left ventricular filling pressure plays an important role in the clinical management of pulmonary hypertension. However, the accuracy of echocardiographic parameters for the determination of left ventricular filling pressure in the presence
Yasuyuki Chiba   +15 more
doaj   +1 more source

Hemodynamic Effects of Ketone Bodies in Patients With Pulmonary Hypertension

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH) are debilitating diseases with a high mortality. Despite emerging treatments, pulmonary vascular resistance frequently remains elevated.
Roni Nielsen   +11 more
doaj   +1 more source

Purinergic Dysfunction in Pulmonary Arterial Hypertension

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Pulmonary arterial hypertension (PAH) is a life‐threatening disease characterized by increased pulmonary arterial pressure and pulmonary vascular resistance, which result in an increase in afterload imposed onto the right ventricle, leading to right ...
Zongye Cai   +4 more
doaj   +1 more source

Targeted therapy with phosphodiesterase 5 inhibitors in patients with pulmonary hypertension due to heart failure and elevated pulmonary vascular resistance: a systematic review

open access: yesPulmonary Circulation, 2020
Pulmonary Hypertension due to left heart disease is the most common type of Pulmonary Hypertension. Morbidity and mortality significantly increase once Pulmonary Hypertension is present.
Galo M. Sanchez Palacios   +2 more
doaj   +1 more source

The effects of genetic deletion of Macrophage migration inhibitory factor on the chronically hypoxic pulmonary circulation

open access: yesPulmonary Circulation, 2020
While it is well established that the haemodynamic cause of hypoxic pulmonary hypertension is increased pulmonary vascular resistance, the molecular pathogenesis of the increased resistance remains incompletely understood. Macrophage migration inhibitory
Lili Li   +7 more
doaj   +1 more source

Transcription factors and potential therapeutic targets for pulmonary hypertension

open access: yesFrontiers in Cell and Developmental Biology, 2023
Pulmonary hypertension (PH) is a refractory and fatal disease characterized by excessive pulmonary arterial cell remodeling. Uncontrolled proliferation and hypertrophy of pulmonary arterial smooth muscle cells (PASMCs), dysfunction of pulmonary arterial ...
Liu Yang   +5 more
doaj   +1 more source

Treatment of exercise pulmonary hypertension improves pulmonary vascular distensibility

open access: yesPulmonary Circulation, 2018
Exercise pulmonary hypertension (ePH) is an underappreciated form of exertional limitation. Despite normal resting pulmonary artery pressures, patients with ePH demonstrate early pulmonary vascular changes with reduced pulmonary arterial compliance (PAC)
William D. Wallace   +3 more
doaj   +1 more source

Case Report of a 23‐year‐old first gravida presenting with breathlessness and oxygen saturation of 80%

open access: yesClinical Case Reports, 2021
Central principles are interdisciplinary teamwork and keeping the ratio between pulmonary vascular resistance (PVR) and systemic vascular resistance (SVR) balanced to avoid vicious circle with right heart failure and hypoxia.
Raphael Porsche   +4 more
doaj   +1 more source

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