Results 91 to 100 of about 96,002 (257)

Type II achalasia unmasked by EndoFLIP and high‐resolution manometry in a child with eosinophilic esophagitis

JPGN Reports, EarlyView.
ABSTRACT Eosinophilic esophagitis (EoE) is a chronic immune‐mediated disease characterized by esophageal dysfunction and eosinophilic inflammation. Persistent dysphagia despite histologic remission should prompt evaluation for alternative etiologies. A 10‐year‐old male with asthma and eczema presented with progressive solid food dysphagia, daily non ...
Rasha Abi Radi Abou Jaoudeh, Jose M. Garza, Chathruckan Rajendra   +2 more
wiley   +1 more source

Biobanking in the Developing World; Maximum Specimens, Minimum Infrastructure

Basic & Clinical Cancer Research, 2018
Biobanking in the Developing World; Maximum Specimens, Minimum ...
Marjan Mohammadi
doaj  

TDP-43-driven alternative splicing of UQCRC2 modulates mitochondrial bioenergetics

Biology Direct
TAR DNA-binding protein 43 (TDP-43) is a nuclear RNA-binding protein. It has emerged as a key regulator of RNA processing, such as alternative splicing events, which are essential for cellular homeostasis.
Xia Xue, Jingwen Hou, Zhiqi Zhang, Zeting Yang, Le Chang, Zengguang Yang, Simeng Liu, Huang Huang, Lu Mei, Yang Mi, Pengyuan Zheng, Xiangdong Sun   +11 more
doaj   +1 more source

Integrative nomogram model based on anoikis-related genes enhances prognostic evaluation in colorectal cancer

Heliyon
Background: Revealing the role of anoikis resistance plays in CRC is significant for CRC diagnosis and treatment. This study integrated the CRC anoikis-related key genes (CRC-AKGs) and established a novel model for improving the efficiency and accuracy ...
Yuexiao Zhang, Xia Xue, Fazhan Li, Bo Zhang, Pengyuan Zheng, Yang Mi   +5 more
doaj   +1 more source

Pediatric hereditary angioedema presenting as recurrent episodic abdominal pain and vomiting: Challenges in diagnosis and management

JPGN Reports, EarlyView.
Abstract Recurrent episodic abdominal pain and vomiting, with symptom‐free intervals between attacks, represent common and often challenging presentations in children, typically leading to extensive workups without a clear etiology, as standard diagnostic algorithms fail to include rare systemic conditions. We present the challenging diagnostic odyssey
Julio Nestor Busaniche, Jhoanna Valery Adauto Luizaga, Maria Soledad Arcucci, Claudio Alberto Salvador Parisi, Judith Cohen Sabban, Agustina Venditti, Valentina Riveros, Giancarlo Testa, Veronica Busoni   +8 more
wiley   +1 more source

Institutional Learning Curve in Esophagectomy: Technical Standardization of Gastric Conduit Formation and Conduit‐Related Outcomes in 187 Consecutive Patients

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Learning curves in esophagectomy are often described in terms of procedural volume, but institutional maturation also reflects progressive standardization of reconstruction, operative choreography, and team‐based decision‐making.
Mayank Tripathi, Reshma R. Balachandran, Kumar Vineet, Dhaval Vadodaria, Vaibhav Kushwaha, Mohd Irfan Ansari, Piyush Shukla   +6 more
wiley   +1 more source

Validation of the Investigator's Global Assessment Scale for Epidermolysis Bullosa Simplex

JEADV Clinical Practice, EarlyView.
ABSTRACT Background There is a lack validated outcome measures to assess wound severity in epidermolysis bullosa simplex (EBS). Objectives To assess the reliability and validity of the Investigator's Global Assessment (IGA) scale and a newly developed palms/soles subscale through in‐clinic scoring and review of patient‐submitted photographs.
Pirunthan Pathmarajah, Shufeng Li, Maya B. Mathur, Joyce M. C. Teng, M. Peter Marinkovich, Austin N. Johnson, Shehla Admani, Edward Eid, Joanna Tu, Dominique C. Mitchell, Lila Perrone, Ricardo Villanueva Gaona, Jean Y. Tang, Albert S. Chiou   +13 more
wiley   +1 more source

Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation–Mediated Reprogramming in Gastric Cancer Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen, Chen‐Kai Liu, Ching‐Chung Tsai, Erna Sulistyowati, Fu‐An Li, Chung‐Jung Liu, Deng‐Chyang Wu, Shih‐Hsuan Chou, Fu‐Chen Kuo, Bin Huang   +9 more
wiley   +1 more source

Single‐Cell Transcriptomics and Deep Learning Link N‐(2‐Furoyl) Glycine to GLRX3 in Gastric Cancer

Med Research, EarlyView.
ABSTRACT Gastric cancer remains a health burden, and its metabolic drivers are poorly defined. N‐(2‐furoyl) glycine, a circulating metabolite, has been implicated in tumor biology. We investigated its causal role in gastric cancer and the underlying mechanism.
Yingyi Zhang, Chenchen Wang, Tianliang Liu, Ziliang Wang, Zhe Zhang   +4 more
wiley   +1 more source

Systemic Impact of Helicobacter pylori: A Cross‐Sectional Study

JGH Open
Background and Aim Helicobacter pylori is an oncobacteria that infects about half of the world's population and has a well‐established role in the etiology of gastric diseases.
Amanda Ferreira Paes Landim Ramos, Silvana Barbosa Santiago, Felipe Augusto deSousa Moraes, Giovana Alice Sampaio Soares, Gisele Aparecida Fernandes, Maria Paula Curado, Janaina Naiara Germano, Mônica Santiago Barbosa   +7 more
doaj   +1 more source