Results 101 to 110 of about 108,821 (298)
Advanced Science, EarlyView.vEMRec is a frequency‐adaptive computational framework for three‐dimensional alignment in volume electron microscopy. It integrates feature‐based rigid alignment with Gaussian filter‐guided elastic registration to correct rigid misalignments and nonlinear distortions while preserving structural fidelity.
Zhenbang Zhang +7 more
wiley +1 more source
Pyramidal neurons of CA1 neuron in organotypic slice
Alzheimer's & DementiaAbstractThis is a maximal intensity projection of CA1 pyramidal cell transfected with plasmid with the reporter GFP using single cell electroporation technique. In this particular case the organotypic slices were prepared from p5‐7 pups in a tissue chopper (McIlwain).
Roy, Avishek +2 more
openaire +1 more source
Encoding and processing of sensory information in neuronal spike trains [PDF]
, 1999 Recently, a statistical signal-processing technique has allowed the information carried by single spike trains of sensory neurons on time-varying stimuli to be characterized quantitatively in a variety of preparations.
Gabbiani, F., Metzner, W.
core +1 more source
, 2013 Channelrhodopsins-2 (ChR2) are a class of light sensitive proteins that offer the ability to use light stimulation to regulate neural activity with millisecond precision.
Khargonekar, Pramod P. +3 more
core +1 more source
Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling
Advanced Science, EarlyView.Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu +20 more
wiley +1 more source
Encoding of spatio-temporal input characteristics by a CA1 pyramidal neuron model.
PLoS Computational Biology, 2010 The in vivo activity of CA1 pyramidal neurons alternates between regular spiking and bursting, but how these changes affect information processing remains unclear.
Eleftheria Kyriaki Pissadaki +3 more
doaj +1 more source
Learning and discrimination through STDP in a top-down modulated associative memory
, 2006 This article underlines the learning and discrimination capabilities of a model of associative memory based on artificial networks of spiking neurons.
Mouraud, Anthony, Paugam-Moisy, Hélène
core +4 more sources
Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling
Advanced Science, EarlyView.Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang +17 more
wiley +1 more source
The mammalian neocortical pyramidal cell: a new theory on prenatal development
Frontiers in Neuroanatomy, 2014 Mammals’ new cerebral cortex (neocortex) and the new type of pyramidal neuron are mammalian innovations that have evolved for operating their increasing motor capabilities using essentially analogous anatomical and neural makeups.
Miguel eMarín-Padilla
doaj +1 more source
In vivo characterization of hippocampal electrophysiological processes in the heterozygous Pten knockout model of autism [PDF]
, 2018 While cognitive deficits have been described in the heterozygous Pten (+/-) KO mouse model of autism, little work has been done to demonstrate how corresponding in vitro physiological alterations in this model may underpin these cognitive deficits in ...
Barry, Jeremy +2 more
core +1 more source