Results 131 to 140 of about 267,739 (297)

A Multi‐Scale Computational Framework for Evaluating Wireless Neuromodulation Feasibility via Magnetoelectric Nanoparticles

open access: yesAdvanced Science, EarlyView.
A multiscale computational framework links single‐nanoparticle magnetoelectric behavior to tissue‐level electric field distributions, integrating experimental data from nanoparticle characterization and in vitro stimulation setups. Applied to a cortical slice configuration, the framework predicts optimal MENP concentrations and stimulation parameters ...
Marta Bonato   +10 more
wiley   +1 more source

Whole-cell recordings from pyramidal neurons in turtle visual cortex.

open access: yes, 2015
Schematic diagram of an isolated piece of turtle dorsal cortex (left panel) with the ventricular side up and containing pyramidal neurons (blue) and interneurons (grey).
Nathaniel Wright (833470)   +4 more
core   +1 more source

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

open access: yesAdvanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi   +8 more
wiley   +1 more source

An operating principle of the cerebral cortex, and a cellular mechanism for attentional trial-and-error pattern learning and useful classification extraction

open access: yesFrontiers in Neural Circuits
A feature of the brains of intelligent animals is the ability to learn to respond to an ensemble of active neuronal inputs with a behaviorally appropriate ensemble of active neuronal outputs. Previously, a hypothesis was proposed on how this mechanism is
Marat M. Rvachev
doaj   +1 more source

Three physiological parameters produce good separation of the two main pyramidal neuron subtypes.

open access: yes, 2015
(A) Representative membrane potential responses to somatic current injections for three pyramidal neurons from each subtype (green/A and magenta/B). Input currents ranged from 50 to 70 pA.
Nathaniel Wright (833470)   +4 more
core   +1 more source

Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures

open access: yesAdvanced Science, EarlyView.
Adult human organotypic cortical slices undergo marked neuronal loss, laminar disruption, and glial activation, yet their network activity progressively stabilizes after a variable period. Electrophysiology, longitudinal calcium imaging, and quantitative histology show that structurally remodeled human circuits show adaptive capacity resulting in ...
Estilla Zsófia Tóth   +20 more
wiley   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

open access: yesAdvanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore   +6 more
wiley   +1 more source

Pyramidal neuron in layer II of the cortex 3 days after a 0.1 µL injection of 3,000 MW BDA.

open access: yes, 2013
(A) The axon of the pyramidal neuron (horizontal arrow) descends to the white matter, but also sends branches (vertical arrows) horizontally. Double arrows indicate the region shown in the inset, rotated 90° clockwise, that illustrates spiny appendages ...
Michael L. Hendrickson (125682)   +2 more
core   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

open access: yesAdvanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li   +12 more
wiley   +1 more source

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