Results 131 to 140 of about 63,189 (307)

Cooptimized Sensing and Sole Mechanics Enable Embodied‐Intelligence Design of User‐Specific Smart Footwear

open access: yesAdvanced Intelligent Systems, EarlyView.
An embodied codesign framework for smart footwear is presented, jointly tuning lattice mechanics and sensing for personalized plantar pressure monitoring. By integrating pneumatic sensing within 3D‐printed lattice soles, the system achieves accurate real‐time centre‐of‐pressure tracking with reduced sensor count and energy demand, demonstrating how ...
Fengyu Zhong   +3 more
wiley   +1 more source

Transition Dynamics of a Dentate Gyrus-CA3 Neuronal Network during Temporal Lobe Epilepsy

open access: yesFrontiers in Computational Neuroscience, 2017
In temporal lobe epilepsy (TLE), the variation of chemical receptor expression underlies the basis of neural network activity shifts, resulting in neuronal hyperexcitability and epileptiform discharges.
Liyuan Zhang, Denggui Fan, Qingyun Wang
doaj   +1 more source

Mode locking in a periodically forced "ghostbursting" neuron model [PDF]

open access: yes, 2004
We study a minimal integrate-and-fire based model of a "ghostbursting" neuron under periodic stimulation. These neurons are involved in sensory processing in weakly electric fish.
Laing, Carlo   +2 more
core   +1 more source

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li   +11 more
wiley   +1 more source

Morpho-electric diversity of human hippocampal CA1 pyramidal neurons

open access: yesCell Reports
Summary: Hippocampal pyramidal neuron activity underlies episodic memory and spatial navigation. Although extensively studied in rodents, extremely little is known about human hippocampal pyramidal neurons, even though the human hippocampus underwent ...
Eline J. Mertens   +20 more
doaj   +1 more source

Neocortical Lamination: Insights from Neuron Types and Evolutionary Precursors

open access: yesFrontiers in Neuroanatomy, 2017
The neocortex is characterized by lamination of its neuron cell bodies in six layers, but there are few clues as to how this comes about and what is its function.
Gordon M. Shepherd, Timothy B. Rowe
doaj   +1 more source

Monoallelic POLR3A Variants Cause Early‐Onset Peripheral Neuropathy

open access: yesAnnals of Neurology, EarlyView.
Objective Biallelic variants in genes encoding the RNA polymerase III complex (Pol III) cause a spectrum of neurological disorders primarily affecting the central nervous system. Monoallelic variants have been reported in the POLR3B subunit only, associated with neurodevelopmental disorder, epilepsy, and peripheral neuropathy.
Luiza L. P. Ramos   +46 more
wiley   +1 more source

Speech Biomarkers for Quantifying Effects of Subthalamic Deep Brain Stimulation in Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective Dysarthria is one of the most common and disabling side effects of subthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson's disease (PD). Stimulation often exacerbates speech dysfunction beyond the effects of PD progression, likely because of current spread to structures surrounding the STN.
Petr Krýže   +17 more
wiley   +1 more source

Gut–Brain Axis Modulation by Short‐Chain Fatty Acids Exerts Disease‐Modifying Effects in a Murine Model of Drug‐Resistant Epilepsy

open access: yesAnnals of Neurology, EarlyView.
Objective Drug‐resistant epilepsy (DRE) remains a clinical challenge, as therapies modifying disease trajectory are lacking. Increasing evidence implicates gut microbiota dysbiosis in epilepsy pathophysiology, with short‐chain fatty acids (SCFAs) emerging as key microbial metabolites with neuroprotective and anti‐inflammatory properties.
Akash A. Bera   +16 more
wiley   +1 more source

F-I curve of the pyramidal neuron model.

open access: yes, 2013
Firing frequency of the pyramidal neuron of the LGN as a function of input current applied to the central cell of the ganglion cell array. The vertical dashed line gives the input current for which the central ganglion cell in the array stops firing (580
Rodrigo Publio (259289)   +2 more
core   +1 more source

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