Virtual dissection of white matter (WM) using diffusion MRI tractography is confounded by its poor reproducibility. Despite the increased adoption of advanced reconstruction models, early region-of-interest driven protocols based on diffusion tensor ...
Ahmed M. Radwan +8 more
doaj +1 more source
Lpd depletion reveals that SRF specifies radial versus tangential migration of pyramidal neurons [PDF]
During corticogenesis, pyramidal neurons (~80% of cortical neurons) arise from the ventricular zone, pass through a multipolar stage to become bipolar and attach to radial glia[superscript 1, 2], and then migrate to their proper position within the ...
Amy L. Norovich +34 more
core +2 more sources
Motor Evoked Potentials Improve Targeting in Deep Brain Stimulation Surgery
Abstract Objectives One of the main challenges posed by the surgical deep brain stimulation (DBS) procedure is the successful targeting of the structures of interest and avoidance of side effects, especially in asleep surgery. Here, intraoperative motor evoked potentials (MEPs) might serve as tool to identify the pyramidal tract.
Petyo Nikolov +7 more
wiley +1 more source
Spinocerebellar Ataxia Type 2 [PDF]
1. Introduction: The autosomal dominant cerebellar ataxias (ADCA) are a clinically, pathologically and genetically heterogeneous group of neurodegenerative disorders caused by degeneration of cerebellum and its afferent and efferent connections.
Auburger, Georg +3 more
core +1 more source
Tracing of Neuronal Connections in the Human Brain by Magnetic Resonance Imaging in vivo [PDF]
Axon degeneration after disruption of fibre tracts in the mammalian nervous system is accompanied by myelin breakdown which leads to changes in its magnetic resonance properties.
Bauer, W. M. +2 more
core +1 more source
The Role of Intraoperative Neurophysiological Monitoring in Intracranial Cavernous Malformation Surgery: A Narrative Review [PDF]
Cavernous malformations, also known as cavernous hemangiomas or cavernomas, are abnormal vascular lesions that can occur in various parts of the body, including intracranially.
Mei Shao +6 more
doaj +1 more source
The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system. [PDF]
Following intracerebral inoculation of adult Balb/c Byj mice, the MHV-4 strain of mouse hepatitis virus (MHV) had an LD50 of less than 0.1 PFU, whereas its monoclonal antibody resistant variant V5A13.1 had an LD50 of 10(4.2) PFU.
Bloom, F +3 more
core +1 more source
Innovative Approach to Understanding Complex Neuroanatomy Through 'Acting-Out', Immersive 3D Modelling. [PDF]
ABSTRACT The challenge persists of engaging students in anatomy education, especially neuroanatomy. Conventional lectures often fail to accommodate the diverse learning preferences of students, leading to disinterest and stress. Innovative teaching methods, such as gamification and interactive learning, have shown promise.
Kulow C, Sandrock M.
europepmc +2 more sources
Axonal regeneration in hippocampal and spinal cord organotypic slice cultures [PDF]
Under normal conditions, axonal regeneration after lesions is not possible in mature CNS but can occur in embryonic and early postnatal nervous systems. In recent years, a number of possible strategies to enhance axonal regeneration and eventually treat ...
Bonnici, Brenda
core +1 more source
Corticospinal Tract (CST) reconstruction based on fiber orientation distributions(FODs) tractography
The Corticospinal Tract (CST) is a part of pyramidal tract (PT), and it can innervate the voluntary movement of skeletal muscle through spinal interneurons (the 4th layer of the Rexed gray board layers), and anterior horn motorneurons (which control ...
Zhang, Youshan
core +1 more source

