Results 91 to 100 of about 20,891 (238)

One-pot synthesis of perhydrofuro[2,3-b]pyran derivatives [PDF]

, 2003
TiCl 4 mediated addition of 3,4-dihydro-2H-pyran to (2-trimethylsilyl)ethyl pyruvate results in a one-pot addition-cyclisation sequence to deliver a functionalised perhydrofuro[2,3-b]pyran derivative in good ...
Flower, SE, Michael C. Willis, Stephen E. Flower, Willis, MC   +3 more
core   +1 more source

5-Acetyl-2-amino-4-(2-fluorophenyl)-6-methyl-4H-pyran-3-carbonitrile dichlomethane hemisolvate

IUCrData
The title compound, 2C15H13FN2O2·CH2Cl2, crystallizes with two main molecules in the asymmetric unit with a disordered dichloromethane solvent molecule.
Carren Nyapola, Sizwe J. Zamisa, Bernard Omondi, Eric M. Njogu   +3 more
doaj   +1 more source

In Vitro Antidiabetic Evaluation and Phytochemical Characterization of Sapindus mukorossi Fruit Pericarp Extract

Applied Research, Volume 5, Issue 4, August 2026.
Sapindus mukorossi fruit pericarp is a promising source of polar polyphenols and amphiphilic saponins, with the 70% ethanol extract showing the richest phytochemical profile and strongest α‐amylase inhibition. Its solvent‐dependent bioactive composition suggests potential application in managing postprandial hyperglycemia by modulating dietary starch ...
Keisham Subharani Devi, Leishangthem Jetlee Singh, Kongbrailatpam Gayatri Sharma, Thokchom Prasanta Singh   +3 more
wiley   +1 more source

Michael reaction of methylenemalonaldehydes: Synthetic approach to 4H-pyran-5-carboxaldehydes and 2-amino-4H-pyran-5-carboxaldehydes [PDF]

, 1987
Base-catalyzed addition of β-dicarbonyl compounds to methylenemalonaldehydes led to tetracarbonyl compounds II which were dehydrated in an acid medium to 4H-pyran-5-carboxaldehydes III.
Jana Hodačová, Vladimír Král, Zdeněk Arnold, Dalimil Dvořák, David Šaman   +4 more
core   +1 more source

Danishefsky’s Diene vs Rawal’s Diene in [4+2] Hetero-Diels-Alder Reactions with Aldehydes

Журнал органічної та фармацевтичної хімії
The Diels-Alder reaction remains one of the most versatile and widely employed cycloaddition strategies in synthetic organic chemistry. The development of functionalized dienes, particularly Danishefsky’s diene (DD) and Rawal’s diene (RD), has ...
Oleksii I. Shamrai, Evgenij V. Zarudnitskii   +1 more
doaj   +1 more source

Urolithin A Exerts Neuroprotective Effects Against Ischemic Stroke by Inhibiting Oxidative Stress and Neuroinflammation

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
Urolithin A (UA) treatment enhances the Nrf2/HO‐1‐mediated antioxidant capacity against ischemic injury postischemic stroke, while also effectively suppressing neuroinflammatory responses. Both of these regulatory effects are likely associated with the NF‐κB signaling pathway, which in turn inhibits neuronal apoptosis and contributes to the improvement
Yanxin Shao, Lina Feng, Yanchun Li, Yichen Cai, Hui Yuan, Qin Tang, Mingfeng Yang, Weixia Yang, Hong Shi, Leilei Mao   +9 more
wiley   +1 more source

Interaction Among Microbiota, Chemical Composition, and Quality Variations in Coffea arabica Across Altitudinal Gradients During Wet Processing

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Fermentation significantly altered the dominant bacterial genera from Sphingomonas and Pleomorphomonas (before fermentation) to Weissella and Lactobacillus (after fermentation), while Cladosporium and Fusarium remained the dominant fungal genera. Notably, non‐volatile compounds in de‐pulping coffee beans and volatile compounds of roasted coffee beans ...
Xiaojing Shen, Yamei Wu, Qi Wang, Wenhua Chen, Bintao Peng, Surui Lu, Ying Yang, Kunyi Liu, Jilai Zhang   +8 more
wiley   +1 more source

Uptake and Transport of Monotropein and Monotropein Esters in a Caco‐2/HT29‐MTX‐E12 Co‐Culture Model

Molecular Nutrition &Food Research, Volume 70, Issue 15, 17 August 2026.
Monotropein and its naturally occurring ester derivatives (monotropein‐10‐coumarate and monotropein‐10‐cinnamate) from Gaultheria spp. berries exhibit limited intestinal permeability in a validated Caco‐2:HT29‐MTX‐E12 co‐culture model. Absorption occurs predominantly via passive diffusion, with partial SGLT1‐ and OATP‐mediated uptake contribution for ...
Christian Zielinski, Victor Schmalle, Luise A. Lauer, Tim Hammerschick, Felix Rüttler, Walter Vetter, Jan Frank, Felipe Jiménez‐Aspee   +7 more
wiley   +1 more source

(6bS*,14R*,14aR*)-Methyl 14-(4-methylphenyl)-7-oxo-6b,6c,7,12b,14,14a-hexahydro-1H-pyrano[3,2-c:5,4-c′]dichromene-14a-carboxylate

Acta Crystallographica Section E, 2013
In the title compound, C28H22O6, the chromeno ring system is almost planar, with a dihedral angle between the mean planes of the pyran and benzene rings of 1.87 (8)°.
R. Ponnusamy, V. Sabari, G. Sivakumar, M. Bakthadoss, S. Aravindhan   +4 more
doaj   +1 more source

Efficient One‐Pot Synthesis of Dibenzoxanthenes Using a Vinylimidazolium‐Based Brønsted Acidic Ionic Liquid [VSBIM][Cl]: In Silico Evaluation of Drug‐Likeness, ADMET Properties, PASS Analysis, Antiviral Activity Prediction, and Molecular Docking Studies

ChemistryOpen, Volume 15, Issue 8, August 2026.
An efficient and solvent‐free sustainable one‐pot protocol is developed for the synthesis of broad range of dibenzoxanthenes using 5 mol% Bronsted acidic ionic liquid [VSBIM][Cl]. The versatility of the methodology was demonstrated by the effective synthesis of 19 dibenzoxanthene derivatives up to 90%–95% yields.
Talamarlla Deepthi, Barnali Maiti
wiley   +1 more source