Results 101 to 110 of about 22,717 (244)

Synthesis of Benzothiophene-Fused Pyran Derivatives via Piperidine Promoted Domino Reaction

open access: yesHeteroatom Chemistry, 2019
A new domino reaction between thioaurones and malononitrile has been reported. This reaction allows efficient access to benzothiophene-fused pyran derivatives in good yields under mild reaction conditions.
Shihang Li   +3 more
doaj   +1 more source

Response Surface Optimization of Ultrasound‐Assisted Deep Eutectic Solvent Extraction of Bioactive Polysaccharides From Sword Bean (Canavalia gladiata (Jacq.) DC.) Pods

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
The polysaccharide from sword been pods (CGPs‑1) demonstrates potent antioxidant activity through DPPH and ABTS radical scavenging (IC50: 31.18 and 2.264 mg/mL), inhibits key carbohydrate‑hydrolyzing enzymes including α‑amylase and α‑glucosidase (IC50: 0.083 and 0.157 mg/mL), reduces MPTP‐induced neuroinflammation in zebrafish embryos (0.1–0.4 mg/mL ...
Jieyu Xing   +5 more
wiley   +1 more source

Polyphenols as Natural Therapeutics for Dental Infections and Oral Inflammation: Mechanisms and Clinical Perspectives

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Polyphenol‐rich plant extracts provide natural immunomodulatory protection for oral health through complementary antioxidant, antibacterial, and anti‐inflammatory actions. Their potential to reduce harmful microbial activity and inflammation highlights the promise of dietary polyphenols as a natural strategy for maintaining oral health and preventing ...
Deepa Subramanian   +3 more
wiley   +1 more source

Botanical, Phytochemistry, Pharmacology and Applications of Genus Heracleum: A Review

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
This manuscript presents a comprehensive review of plant species in the genus Heracleum, from botanical classification and distribution to medicinal uses, phytochemistry, pharmacology, and applications, aiming to provide references for further exploration of their therapeutic value and research development.
Nan Zhang   +5 more
wiley   +1 more source

Novel Michael-Wittig reactions of methyl 3-oxo-4-(triphenylarsoranylidene)butanoate and substituted 2H-pyran-5-carboxylates; The synthesis of highly functionalised 2-cyclohexenonedicarboxylates

open access: yes, 1997
Novel Michael-Wittig condensations of methyl 3-oxo-4-(triphenylarsoranylidene)-butanoate 6 and substituted 2,2-dimethyl-2H-pyran-5-carboxylates 5a to 5e gave substituted 4-alkyl-6-oxo-4-cyclohexene-1,3-dicarboxylates 8a to 8e in a mixture of three keto ...
Moorhoff, CM (15481859)
core  

Novel functionalized monomers based on kojic acid: snythesis, characterization, polymerization and evalution of antimicrobial activity

open access: yesDesigned Monomers and Polymers, 2017
Two novel acrylate monomers, [5-(benzyloxy)-4-oxo-4H-pyran-2-yl]methyl acrylate and {1-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)methyl]-1,2,3-triazol-4-yl}methyl acrylate were synthesized by the reaction of 5-benzyloxy-2-(hydroxymethyl)-4H-pyran-4-one and 5 ...
Mahnaz Saraei   +3 more
doaj   +1 more source

Green MW/US‐Assisted Construction of Pyrano[2,3‐b]pyridines and Pyrazolo[3,4‐d]pyrimidinones: Pathway Control and Antibacterial Evaluation

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
A rapid, green MW/US‐assisted route was developed for synthesizing coumarin/azacoumarin‐based fused heterocycles. It enables efficient construction of pyrano[2,3‐b]pyridines and pyrazolo[3,4‐d]pyrimidinones under mild conditions. FT‐IR, NMR, MS, and elemental analysis fully confirmed the structures of the new products.
Sultanah M. Alhunayhin   +5 more
wiley   +1 more source

A substituent-controlled general approach to access arylated pyran-2-ones and pyrano[3,4-c]pyran-1,8-diones

open access: yes, 2007
2H-Pyran-2-ones are useful precursors for the synthesis of various aromatic and heterocyclic compounds. In this Letter, we describe substituent-controlled direct access to functionalized 4-(2-oxo-1,2-diarylethyl)-5,6-diaryl-pyran-2-ones by stirring a ...
Raghunandan, Resmi   +5 more
core   +1 more source

Metabolomics Analysis Revealed That SXZ Ameliorates Cognitive Impairment in Naturally Aged Rats by Promoting Glutathione Metabolism and Inhibiting the Ferroptosis Pathway

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
In aged rats, 6‐month SXZ treatment reversed spatial memory deficits and preserved hippocampal integrity. Mechanistic assays show that SXZ promotes glutathione metabolism and inhibits ferroptosis via p53/SLC7A11/GPX4 and Keap1/Nrf2/HO‐1 pathways. SXZ is a novel neuroprotective agent against age‐related cognitive decline.
Mengya Liu   +6 more
wiley   +1 more source

Enzymatic Pyran Formation Involved in Xiamenmycin Biosynthesis

open access: yes, 2019
The pyran ring is a very common structural unit of many natural, bioactive molecules that are widely found in plants, bacteria, and fungi. However, the enzymatic processes by which many of these pyran-containing molecules are formed are unclear.
Yi-Lei Zhao (800876)   +17 more
core   +1 more source

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