Abstract The regio‐ and stereoselective hydroxylation of unactivated C(sp3)‐H bonds is an important reaction in organic synthesis. While bacterial alkane monooxygenase AlkB catalyzes the terminal hydroxylation of aliphatic esters with excellent regioselectivity, the molecular principles of substrate recognition and selectivity of this integral membrane
Jelena Spasic +8 more
wiley +1 more source
ABSTRACT Berries of Lonicera caerulea (blue honeysuckle; haskap) have been used since ancient times in traditional medicine in China, Japan, and northern Russia. This study aimed to extract, characterize, and evaluate the biological activity of iridoid‐rich fractions from haskap berries using an in vitro adipocyte model.
Liangchuan Guo +5 more
wiley +1 more source
On the enigmatic scent glands of dyspnoan harvestmen (Arachnida, Opiliones): first evidence for the production of volatile secretions [PDF]
La utilización en encuestas de preguntas con tarjetas de respuesta está totalmente aceptada por la comunidad investigadora. Esto supone una carga de trabajo “extra” en la tarea del entrevistador, lo que explica que en ocasiones no se utilicen ...
Günther Raspotnig +4 more
core +4 more sources
Bis‐Furans: A Sustainable Source of Diverse Molecular Architectures
A concise synthetic route to diverse acyclic and heterocyclic compounds has been developed by combining hetero‐Diels–Alder reactions, DBU‐promoted ring openings, and Lewis base‐catalyzed annulations. Nitrosoalkenes reacted with furan derivatives to form 4a,7a‐dihydro‐4H‐furo[2,3‐e][1,2]oxazines, which underwent DBU‐promoted rearrangements to 6H‐1,2 ...
Ana L. Cardoso +2 more
wiley +1 more source
An analysis of double exposure lithography options [PDF]
The current optical photolithography technology is approaching the physical barrier to the minimum achievable feature size. To produce smaller devices, new resolution enhancement technologies must be developed.
Byers, Jeffrey +6 more
core +2 more sources
KCa 3.1-a microglial target ready for drug repurposing? [PDF]
Over the past decade, glial cells have attracted attention for harboring unexploited targets for drug discovery. Several glial targets have attracted de novo drug discovery programs, as highlighted in this GLIA Special Issue.
Dale, E, Eder, C, Möller, T, Staal, RGW
core +1 more source
Electronic structure of tetraphenyldithiapyranylidene : A valence effective Hamiltonian theoretical investigation [PDF]
We present a theoretical investigation of the electronic structure of tetraphenyldithiapyranylidene (DIPSΦ4) using the nonempirical valence effective Hamiltonian (VEH) method.
Ortí Guillén, Enrique +2 more
core +2 more sources
Synthesis of selected naturally occurring glucosides of volatile compounds. Their chromatographic and spectroscopic properties [PDF]
Naturally occurring glucosides of benzyl alcohol, (+/-)-menthol, (+)-borneol, thymol, carvacrol and eugenol were synthesized by the Koenigs-Knorr-Zemplen method (yields 19.5-52.2%). Their beta-D-glucopyranosidic structures were determined by one- and two-
Džolić, Zoran +4 more
core +1 more source
Photolysis at long wavelengths of amino acid ester derivatives based on 4-methyl-6-methoxy-2-oxo-2H-naphtho[1,2-b]pyrans [PDF]
Ester derivatives of fused 4-methyl-6-methoxy-2-oxo-2H- naphtho[1,2-b]pyran, using valine and phenylalanine as model bifunctional molecules were synthesised, to assess its applicability as a photocleavable protecting group, for solution phase organic ...
Costa, Susana P. G. +4 more
core
Cleavages of photochromic compounds derived from heterocycles under electrospray tandem mass spectrometry : study of the influence of the heteroatom in fragmentation mechanisms [PDF]
In this paper we report the fragmentation pathways of chromenes derived from carbazole, dibenzofuran and dibenzothiophene, under ESI-MS/MS experimental conditions, and their relationship with structural features, specially focused on the heteroatom’s ...
Campos, Ana M. F. Oliveira +5 more
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