Results 81 to 90 of about 3,742 (239)

Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds

The Chemical Record, EarlyView.
This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá, Patrick C. Nobre, Isabelly O. Ferreira, Juliano B. Azeredo, Vanessa Nascimento   +4 more
wiley   +1 more source

Entry to new spiroheterocycles via tandem Rh(II)-catalyzed O–H insertion/base-promoted cyclization involving diazoarylidene succinimides

Beilstein Journal of Organic Chemistry
A facile approach to novel medicinally relevant spiro heterocyclic scaffolds (namely furan-2(5H)-ones, tetrahydrofurans and pyrans spiro-conjugated with the succinimide ring) has been developed.
Alexander Yanovich, Anastasia Vepreva, Ksenia Malkova, Grigory Kantin, Dmitry Dar’in   +4 more
doaj   +1 more source

Multi component one pot synthesis and characterization of derivatives of 2-amino-7,7- dimethyl-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile and study of anti-microbial activity

Bulletin of the Chemical Society of Ethiopia, 2018
An efficient and convenient procedure has been described for one-pot multi-component synthesis of tetrahydrobenzo[b]pyrans known as 2-amino-7,7-dimethyl-5-oxo-4-phenyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile which can be obtained from the reaction ...
N. K. Rao, T. N. Rao, B. Parvatamma, K. P. Devi, S. C. Setty   +4 more
doaj   +1 more source

An efficient three-step synthesis of cyclopenta[b]pyrans via 2-donor-substituted Fischer ethenylcarbenechromium complexes

, 2005
A wide range of cyclopenta[b]pyrans 4 has been synthesized in a one-pot reaction by treatment of different 2-donorsubstituted ethenylcarbene-chromium complexes 2 with alkynes in THF in moderate to excellent yields (41-90% for 14 out of 25 examples).
Funke, Frank, Belgardt, T., Schimer, H., de Meijere, Armin, Noltemeyer, M., Stein, F., Duetsch, Michael, Wu, Y., Knieriem, B.   +8 more
core   +1 more source

Sulfur‐ and Selenium‐Decorated Coumarins: Synthetic Strategies Involving Cyclization and Late‐Stage Functionalization

The Chemical Record, EarlyView.
Two decades of synthetic strategies for sulfur‐, selenium‐decorated coumarins are critically surveyed through 44 literature reports, with particular emphasis on derivatives functionalized at the C‐3 and C‐4 positions. This review reports the direct construction of the coumarin framework through cyclization processes and late‐stage functionalization of ...
Bruna R. Schneider, Laura D. de Avila, Mauricio C. D. F. Xavier, Alex F. C. Flores, Liane K. Soares, Gabriel P. da Costa, Angelita M. Barcellos   +6 more
wiley   +1 more source

Hydroxycinnamic Acid Amides Emerge as Multifunctional Molecules Involved in Regeneration and Volatile Signalling During Wound Responses

Plant, Cell &Environment, EarlyView.
ABSTRACT Hydroxycinnamic acid amides (HCAAs) are phenylpropanoid‐derived metabolites traditionally associated with antimicrobial defence and cell wall reinforcement during plant–pathogen interactions. However, their contribution to plant responses to mechanical injury, particularly in wound healing and damage‐induced signalling, remains poorly ...
Carmen Grech‐Hernández, Andrade Cynthia, Francisco Vera‐Sirera, Álvaro Luis Jiménez‐Jiménez, Marc Valls, Nuria S. Coll, Ismael Rodrigo, José María Bellés, María Pilar López‐Gresa, Purificación Lisón   +9 more
wiley   +1 more source

Sharing of 4‐hydroxy‐3‐(methylthio)benzaldehyde as a pollination semiochemical among distantly related sexually deceptive orchids

Plant Biology, EarlyView.
We demonstrate that Spiculaea ciliata attracts male Thynnoturneria abspiculus through a single semiochemical, identified as 4‐hydroxy‐3‐(methylthio)benzaldehyde, emitted from its labellum. This compound alone elicited sexual behaviours in male wasps comparable to those elicited by whole floral extracts and attracted wasps when presented on a synthetic ...
S. K. van Kints, G. R. Flematti, M. V. Baker, R. Peakall, R. D. Phillips, B. Bohman   +5 more
wiley   +1 more source

Integrated Phytochemical Characterisation, Pharmacological Evaluation and Computational Investigation of Acampe papillosa Stem Extract

Analytical Science Advances, Volume 7, Issue 2, December 2026.
The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia, Sadia Tamanna Tamim, Faruq Mohammed Tashriq, Nasir Uddin, Fatematus Zhohara Alam Hima, Ulfat Sobha Surat, Mily Khastagir, Muhammad Abdul Jalil, Md. Hossain Rasel, Arman Ullah Rafi, S. M. Moazzem Hossen   +10 more
wiley   +1 more source

Addition of lithiated enol ethers to nitrones and subsequent Lewis acid induced cyclizations to enantiopure 3,6-dihydro-2H-pyrans – an approach to carbohydrate mimetics

Beilstein Journal of Organic Chemistry, 2010
A stereodivergent synthesis of enantiopure 3,6-dihydro-2H-pyrans is presented. The addition of lithiated enol ethers to carbohydrate-derived nitrones afforded syn- or anti-configured hydroxylamine derivatives 4a–d that were cyclized under Lewis acidic ...
Fabian Pfrengle, Hans-Ulrich Reissig
doaj   +1 more source

Stimulation of Antibody Formation by Pyran Copolymer

Experimental Biology and Medicine, 1970
SummaryPyran copolymer, administered with sheep red blood cells to mice, enhances the early rate of appearance of antibody-forming spleen cells. Although the cytotoxicity and pyrogenicity of pyran and bacterial endotoxins are similar, pyran, in contrast to endotoxin, does not trigger a nonspecific initiation of antibody formation; it only enhances ...
W, Braun, W, Regelson, Y, Yajima, M, Ishizuka   +3 more
openaire   +2 more sources