Results 91 to 100 of about 3,431 (233)

Urolithin A Exerts Neuroprotective Effects Against Ischemic Stroke by Inhibiting Oxidative Stress and Neuroinflammation

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
Urolithin A (UA) treatment enhances the Nrf2/HO‐1‐mediated antioxidant capacity against ischemic injury postischemic stroke, while also effectively suppressing neuroinflammatory responses. Both of these regulatory effects are likely associated with the NF‐κB signaling pathway, which in turn inhibits neuronal apoptosis and contributes to the improvement
Yanxin Shao   +9 more
wiley   +1 more source

Interaction Among Microbiota, Chemical Composition, and Quality Variations in Coffea arabica Across Altitudinal Gradients During Wet Processing

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
Fermentation significantly altered the dominant bacterial genera from Sphingomonas and Pleomorphomonas (before fermentation) to Weissella and Lactobacillus (after fermentation), while Cladosporium and Fusarium remained the dominant fungal genera. Notably, non‐volatile compounds in de‐pulping coffee beans and volatile compounds of roasted coffee beans ...
Xiaojing Shen   +8 more
wiley   +1 more source

Synthesis of novel substituted tetrahydropyridines, pyrans and thiopyrans [PDF]

open access: yes, 2004
2459-2463A new class of six membered heterocycles, 4,4-disubstituted 2,6-diaryl-3,5-diaroyl tetrahydropyridines/pyrans/thiopyrans are synthesized from 1,5-diaryl-3,3 dimethoxycarbonyl-1,5-pentanedione 1/1,5 -diaryl-3-cyano-3-ethoxycarbonyl-1,5 ...
Padmavathi, V   +3 more
core  

A Domino Strategy for the Synthesis of 2H‐Pyrans from Propargyl Vinyl Ethers [PDF]

open access: yes, 2019
Stable monocyclic 2H‐pyrans are synthesized from readily available tertiary propargyl vinyl ethers via a metal‐free all‐pericyclic domino manifold involving a sequential propargyl Claisen rearrangement/[1,3]H‐shift/oxa‐6π electrocyclization set of ...
Delgado-Hernández, Samuel   +4 more
core   +1 more source

Uptake and Transport of Monotropein and Monotropein Esters in a Caco‐2/HT29‐MTX‐E12 Co‐Culture Model

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 15, 17 August 2026.
Monotropein and its naturally occurring ester derivatives (monotropein‐10‐coumarate and monotropein‐10‐cinnamate) from Gaultheria spp. berries exhibit limited intestinal permeability in a validated Caco‐2:HT29‐MTX‐E12 co‐culture model. Absorption occurs predominantly via passive diffusion, with partial SGLT1‐ and OATP‐mediated uptake contribution for ...
Christian Zielinski   +7 more
wiley   +1 more source

Flexible synthesis of spirocyclic pyrans and piperidines [PDF]

open access: yes, 2012
Spirocyclic piperidines and spirocyclic pyrans are prevalent throughout nature, often appearing in natural products which exhibit exciting biological activities.
Ferrari, Frank D.
core  

Meglumine: A Novel and Efficient Catalyst for One-Pot, Three-Component Combinatorial Synthesis of Functionalized 2‑Amino‑4H‑pyrans [PDF]

open access: yes, 2016
An efficient one-pot synthesis of functionalized 2-amino-4H-pyrans by a meglumine-catalyzed three-component reaction has been developed. A broad range of substrates including aromatic and heteroaromatic aldehydes, isatin derivatives, and ...
Rui-Zhi Wang (1887556)   +6 more
core   +1 more source

Efficient One‐Pot Synthesis of Dibenzoxanthenes Using a Vinylimidazolium‐Based Brønsted Acidic Ionic Liquid [VSBIM][Cl]: In Silico Evaluation of Drug‐Likeness, ADMET Properties, PASS Analysis, Antiviral Activity Prediction, and Molecular Docking Studies

open access: yesChemistryOpen, Volume 15, Issue 8, August 2026.
An efficient and solvent‐free sustainable one‐pot protocol is developed for the synthesis of broad range of dibenzoxanthenes using 5 mol% Bronsted acidic ionic liquid [VSBIM][Cl]. The versatility of the methodology was demonstrated by the effective synthesis of 19 dibenzoxanthene derivatives up to 90%–95% yields.
Talamarlla Deepthi, Barnali Maiti
wiley   +1 more source

Stereoselective syntheses of benzo- and naphtho-pyrans by Lewis acid catalysed isomerisation of aryldioxolanes [PDF]

open access: yes, 1991
Phenyl- and naphthyl-dioxolanes are stereoselectively isomerised using titanium tetrachloride in methylene dichloride at -78°C into benzo- and naphtho ...
Lee Son, V.R.   +5 more
core  

13C NMR Analysis of 3,6-Dihydro‑2H‑pyrans: Assignment of Remote Stereochemistry Using Axial Shielding Effects [PDF]

open access: yes, 2016
The rational analysis of 13C NMR axial shielding effects has enabled the assignment of remote relative stereochemistry in 3,6-oxygen-substituted 3,6-dihydro-2H-pyrans. Comparison of the 13C NMR shifts of equivalent centers in cis- and trans-substituted 3,
Mark J. Bartlett (1390633)   +3 more
core   +1 more source

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