Results 41 to 50 of about 2,505 (153)

Evaluation of the speed of kill of a novel orally administered combination product containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against induced infestations of Ixodes scapularis on dogs

Parasites & Vectors, 2020
Background The black-legged (or deer) tick, Ixodes scapularis, commonly infests dogs in the USA and is the vector of important zoonotic pathogens, including Borrelia burgdorferi, the causative agent of Lyme disease.
Susan Holzmer, Kristina Kryda, Sean P. Mahabir, William Everett   +3 more
doaj   +1 more source

Efficacy of a new oral chewable tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against induced ascarid infections in dogs

Parasites & Vectors, 2020
Background Ascarid infections are among the most prevalent intestinal parasitic infections occurring in dogs around the world, with Toxocara canis and Toxascaris leonina commonly observed. Toxocara canis can cause considerable disease in dogs and humans,
Csilla Becskei, Kristina Kryda, Mirjan Thys, Susan Holzmer, Laurel Bowersock, Tiago Fernandes, Leon Meyer, Craig Reinemeyer, Sean P. Mahabir   +8 more
doaj   +1 more source

Efficacy of a novel orally administered combination product containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against induced infestations of five common tick species infesting dogs in the USA

Parasites & Vectors, 2020
Background The efficacy of a novel oral combination product, Simparica Trio™, containing sarolaner, moxidectin and pyrantel was evaluated against five tick species that commonly infest dogs in the USA, Amblyomma americanum, Amblyomma maculatum ...
Kristina Kryda, Sean P. Mahabir, Sara Chapin, Susan J. Holzmer, Laurel Bowersock, William R. Everett, John Riner, Lori Carter, David Young   +8 more
doaj   +1 more source

Pyrantel and oxantel pamoate

, 2017
Pyrantel, E-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl) vinyl]-pyrimidine, is an imidazothiazole-derived tetrahydropyrimidine. Its anthelmintic activity was first identified in 1966 (Austin et al., 1966). It has been used as a broadspectrum anthelmintic
Kopp, Steven, Keiser, Jennifer
core   +1 more source

Dose response relationship of oxantel pamoate combinations against T. muris in vitro.

, 2013
Oxantel pamoate-levamisole (blue line), oxantel pamoate-ivermectin (green line), oxantel pamoate-mebendazole (red line), oxantel pamoate-pyrantel pamoate (pink line) and oxantel pamoate-albendazole (orange line) were combined using ratios based on their ...
Angelika Silbereisen (336565), Roberto Adelfio (392660), Mireille Vargas (392661), Jennifer Keiser (39606), Benjamin Speich (159922), Lucienne Tritten (336564)   +5 more
core   +1 more source

Pyrantel Pamoate in Roundworm Infestations [PDF]

, 2017
A controlled single-blind trial was carried out to compare the effect of single-dose therapy with pyrantel pamoate (Combantrin) and piperazine citrate in children infested with Ascaris lumbricoides. Fifty-six children were treated.
de Villiers, DJ, Isaacson, M, Hatchuel, W   +2 more
core  

A Survey of Toxocariasis Among Household and Stray Puppies in Gokarneshwor Municipality, Kathmandu, Nepal

International Journal of Zoology, Volume 2026, Issue 1, 2026.
Introduction Toxocariasis is a zoonotic parasitic disease affecting humans and domestic pets, leading to significant morbidity and, in severe cases, mortality. This study aimed to determine the prevalence of Toxocara canis among household and stray/free‐ranging puppies aged ≤ 6 months in Gokarneshwor Municipality, central Nepal.
Roshan Babu Adhikari, Luniva Shrestha, Niva Shrestha, Saroj Khatiwada, Tirth Raj Ghimire, Lipi Buch   +5 more
wiley   +1 more source

Efficacy of a chewable tablet containing sarolaner, moxidectin, and pyrantel (Simparica Trio®) in the treatment of sarcoptic mange caused by Sarcoptes scabiei mite infestations in dogs

Parasites & Vectors, 2023
Background Infestation with Sarcoptes scabiei in dogs is a debilitating disease if left untreated and is transmissible to humans. Two field studies were conducted to confirm the efficacy of orally administered sarolaner in combination with moxidectin and
Csilla Becskei, Julian Liebenberg, Tiago Fernandes, Stasia Borowski, Lina D’Hanis, Sean P. Mahabir   +5 more
doaj   +1 more source

Development and Validation of a Multiplex Flow Cytometry‐Based PBMC Assay for Immunomodulator Screening

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
The identification of novel compounds capable of stimulating or suppressing immune responses is critical for advancing immunotherapy and improving our understanding of immune regulation. However, traditional screening approaches are often limited by low throughput, poor physiological relevance, and insufficient resolution to detect subtle ...
Regine Brox, Holger Hackstein, Poorani Gurumallesh Prabu   +2 more
wiley   +1 more source

Therapeutic efficacy of a three-component anthelmintic drug against cestodosis and nematodosis of small domestic animals

Российский паразитологический журнал
The purpose of the study therapeutic efficacy of combined anthelmintic drug on dogs and cats of different age groups naturally infected with cestodes and nematodes.Materials and methods.
T. S. Filatova
doaj   +1 more source