Results 141 to 150 of about 27,892 (233)

1,1'-Thiocarbonyl-bis-pyrazoles. Part II. Substituent Effects on Rates of Ethanolysis. [PDF]

, 1970
Lars-Ola Carlsson, Jan Sandström, Hans Hjeds, Bodil Jerslev, Claus Erik Schäffer, Erling Sunde, Nils Andreas Sörensen   +6 more
openalex   +1 more source

Sex differences in the vasoactive effect of transient receptor potential channels: TRPM3 as a new therapeutic target for (neuro)vascular disorders

British Journal of Pharmacology, Volume 182, Issue 11, Page 2503-2523, June 2025.
Abstract Background and Purpose Sex‐dependent vascular effects of transient receptor potential (TRP) channels and sex dimorphism in migraine are not yet fully characterized. We investigated the differential vasoactive effects of TRP ankyrin 1 (TRPA1), TRP melastatin 3 (TRPM3) and TRP vanilloid 1 (TRPV1) channels, their pharmacological mechanism(s), and
Eduardo Rivera‐Mancilla, Usha M. Musterd‐Bhaggoe, Dennis Schutter, Antoon van den Bogaerdt, Arnaud J. P. E. Vincent, Carlos M. Villalón, Alexander H. J. Danser, Antoinette MaassenVanDenBrink   +7 more
wiley   +1 more source

Are activation barriers of 50-70 kcal mol^-1 accessible for transformations in organic synthesis in solution? [PDF]

Chem Sci
Shaydullin RR, Galushko AS, Ilyushenkova VV, Vlasova YS, Ananikov VP.   +4 more
europepmc   +1 more source

Synthesis of N-Aryloxy (or thio)acetyl/ acetamido Pyrazoles and Pyrroles [PDF]

, 1979
M. IMTIAZ HUSAIN, G. C. SRIVASTAVA
openalex   +1 more source

Design and Synthesis of Tetrahydropyrrolo[3,4‐c]Pyrazole Sigma‐1 Receptor Ligands

ChemMedChem, Volume 20, Issue 9, May 5, 2025.
This study highlights the tetrahydropyrrolo[3,4‐c]pyrazole scaffold as a promising platform for S1R ligands development. Key findings include compound 19’s high S1R affinity (Ki=75 nM), influenced by strategic nitrogen substitutions and reduced steric hindrance.
Giuseppe Cosentino, Maria Dichiara, Giuliana Costanzo, Alessandro Coco, Lorella Pasquinucci, Agostino Marrazzo, Antonio Rescifina, Emanuele Amata   +7 more
wiley   +1 more source

The synthesis and investigation of novel 3-benzoylbenzofurans and pyrazole derivatives for anti-HIV activity. [PDF]

RSC Med Chem
Khuzwayo SS, Selepe MA, Meyer D, Gama NH.   +3 more
europepmc   +1 more source

Studies in Heterocyclic Compounds : Part IV. Synthesis of some 3-Methyl-5-aryl-4-(substituted sulphonamidobenzeneazo) pyrazoles and their Screening for Antibacterial Properties [PDF]

, 1975
CHANDRA MOHAN, G. S. SAHARIA, H. R. SHARMA   +2 more
openalex   +1 more source

Regioselective C‐H Thio‐ and Selenocyanation of Pyrazolo[1,5‐a]pyrimidines

Chemistry – An Asian Journal, Volume 20, Issue 9, May 2, 2025.
A metal‐free, N‐chlorosuccinimide (NCS) mediated, highly efficient, and regioselective C−H thiocyanation and C−H selenocyanation of pyrazolo[1,5‐a]pyrimidines are achieved under mild reaction conditions for the synthesis of a wide variety of 3‐thiocyanato‐ and 3‐selenocyanatopyrazolo[1,5‐a]pyrimidines in good to excellent yield up to 99 %.
Paramita Pattanayak, Harshil Khandelwal, Shreeja Basappa, Tanmay Chatterjee   +3 more
wiley   +1 more source

Antifungal activity and biocompatibility assessment with molecular docking and dynamic simulations of new pyrazole derivatives. [PDF]

BMC Biotechnol
Abd-Elhalim BT, El-Bana GG, El-Sayed AF, Abdel-Ghani GE.   +3 more
europepmc   +1 more source

Studies on Fungicides. VII. Synthesis and Antifungal Activity of Some Pyrazole Derivatives.

, 1964
Jiro Kinugawa, Michihiko Ochiai, Chikashi Matsumura, Hiroichi Yamamoto   +3 more
openalex   +2 more sources