Results 131 to 140 of about 37,807 (249)

Correlation Between the Molecular Structure of Metal‐Supporting Ligands and Catalysis in the Oxygenase‐Mimicking Immobilized Metal Complex Catalysts

European Journal of Inorganic Chemistry, Volume 29, Issue 16, 4 June 2026.
The correlation between the structures of metal complexes immobilized in the mesopores of hydrophobically modified silicate supports was examined in relation to the catalytic activities toward C‐H oxidation. On the alkene oxidation with H2O2, the iron catalyst bearing bis(imidazolyl)methane ligand promotes allylic oxidation, whereas the mononuclear ...
Yuta Akizawa, Hiroe Fukuzaki, Nana Aizawa, Sho Ikeda, Airi Kawabe, Saori Nishiyama, Iori Nagasawa, Masaya Okamura, Shiro Hikichi   +8 more
wiley   +1 more source

Regioselective synthesis of 1,3,5- and 1,3,4,5-substituted pyrazoles via acylation of N-Boc-N-substituted hydrazones

, 2011
Acylation of N-Boc-N-methylhydrazones followed by TFA treatment affords regioselective access to substituted pyrazoles. Both regioisomers of 1-methyl-3,5-disubstituted-1H-pyrazoles can be selectively obtained.
Daniele Andreotti, ROSINI, GOFFREDO, RIGHI, PAOLO, Paolo Righi, R. Profeta, D. Andreotti, S. Spada, Roberto Profeta, Simone Spada, TINARELLI, ALESSANDRO, Alessandro Tinarelli, Goffredo Rosini   +11 more
core   +1 more source

Structural and Chemical Engineering of Sub‐Nanochannel Membranes Toward Ion Selectivity

Advanced Functional Materials, Volume 36, Issue 46, 8 June 2026.
This review summarizes recent advances in structural and chemical engineering of sub‐nanochannels for ion selectivity. We first introduce fundamental ion transport mechanisms within sub‐nanochannels, followed by strategies to tune pore size, geometry, and surface functionalities, categorized into charge‐based, ion‐recognition, hydrophilic bonding, and ...
Yuyu Su, Huacheng Zhang, Tamar L. Greaves, Qi Han, Weiwei Lei, Dan Liu   +5 more
wiley   +1 more source

A new route to the synthesis of imidazo [4,5-c]pyrazoles

, 1988
A new synthesis of imidazo [4,5-c] pyrazoles, obtained through cyclisation of 4-nitroso-5-alkylamino-pyrazoles, is described ...
GIORI, Paolo, VERONESE, Augusto, Augusto Cesare Veronese, VICENTINI, Chiara Beatrice, Chiara Beatrice Vicentini, Paolo Giori, GUARNERI, Mario, Mario Guarneri   +7 more
core   +1 more source

-Propargyl Pyrazoles

, 2015
A concise synthetic methodology for new heterocyclic scaffolds, such as pyrazolo-pyrrolo-pyrazine and pyrazolo-pyrrolo-diazepine skeletons, was developed. The key features of this method include (i) synthesis of pyrrole-derived alpha,beta-alkynyl ketones,
Sinan Basceken, Basceken, Sinan, Balcı, Metin, BALCI, METİN, Balcı, Mehmet, Metin Balci   +5 more
core   +1 more source

AMINO-PYRAZOLES: A PRIVILEGED SCAFFOLD FOR THE SYNTHESIS OF BIOLOGICALLY ACTIVE COMPOUNDS

, 2023
Taking as lead structures previous reported pyrazoles, we designed and synthesized novel series of pyrazoles 2-5. All the isolated molecules were prepared by a stepwise protocol that allowed the preparation of N,S-thioketal intermediates which were then ...
Matteo Lusardi
core  

Light‐Driven [2 + 2] Cycloaddition Strategies for the Synthesis of Cyclobuta[b]indoles and Their Derivatives

ChemPhotoChem, Volume 10, Issue 6, June 2026.
This review surveys the literature on light‐driven dearomative [2+2] cycloadditions of indoles, highlighting their power to access complex cyclobuta[b]indole frameworks. Advances in photocatalysis, sensitizer design, and reaction engineering enable selective and sustainable assembly of strained three‐dimensional architectures, expanding opportunities ...
Maria Chiara Cabua, Davide Moi, Alberto Luridiana, Francesco Secci, Emanuele Cocco   +4 more
wiley   +1 more source

The Role of N6‐Methyladenosine Modification in Health and Disease

MedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li, Yuanhai Sun, Wanfang Zheng, Lingqin Li, Yaqian Feng, Minyou Qi, Hanbing Li   +6 more
wiley   +1 more source

Unveiling the Power of Deuterium in Drug Discovery: A Comprehensive Overview

MedComm, Volume 7, Issue 6, June 2026.
The role of deuterium replacement in drug discovery, its progress, opportunities, and challenges. ABSTRACT Deuterium, the heavy isotope of hydrogen, has unfolded as a cornerstone in modern drug discovery due to its potential to influence metabolic stability and pharmacokinetic behavior.
Mukta Lele, Ajit Manchare, Swapnali Parit, Amol D. Gholap, Krishna Jadhav, Navnath Hatvate, Keshav Raj Paudel, Satish Rojekar   +7 more
wiley   +1 more source

Diazo Transfer From Nitrous Oxide Employing Phosphorus Ylides

Angewandte Chemie, Volume 138, Issue 22, 25 May 2026.
A phosphorus ylide‐mediated strategy achieves the direct fixation of nitrous oxide (N2O) to access diazo compounds, which after intra‐ or intermolecular trapping, afford N2‐containing organic building blocks. This approach provides an alternative to hazardous diazo‐transfer reagents and establishes N2O fixation as a sustainable methodology.
Jhen‐Kuei Yu, Jan Niclas Ludwig, Patrick Wolf Antoni, David Tymann, Max Martin Hansmann   +4 more
wiley   +2 more sources