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Alkynes and Nitrogen Compounds: Useful Substrates for the Synthesis of Pyrazoles
Chemistry - A European Journal, 2020 The easy preparation and functionalization of pyrazoles associated with their innumerable biological properties have made this class of N -heterocycles very attractive for the development of new synthetic routes and applications.
Gilson Zeni, Jose S S Neto
exaly +2 more sources
Magnetic Resonance in Chemistry, 1993 The carbon-13 chemical shifts and coupling constants of 1168 pyrazoles are reported, some of them in several solvents. These data are briefly discussed on the basis of statistical treatment and qualitative comparisons.Peer ...
Rosa M Claramunt +2 more
exaly +3 more sources
A Unified Continuous Flow Assembly-Line Synthesis of Highly Substituted Pyrazoles and Pyrazolines
Angewandte Chemie - International Edition, 2017 A rapid and modular continuous flow synthesis of highly functionalized fluorinated pyrazoles and pyrazolines has been developed. Flowing fluorinated amines through sequential reactor coils mediates diazoalkane formation and [3+2] cycloaddition to ...
Joshua Britton, Timothy F. Jamison
exaly +2 more sources
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International Journal of Biological Macromolecules, 2021
Type 2 diabetes mellitus (DM) is a complex chronic disorder and a major global health problem. Insulin resistance is the primary detectable abnormality and the main characteristic feature in individuals with type 2 DM.
Sónia Rocha +10 more
semanticscholar +1 more source
Type 2 diabetes mellitus (DM) is a complex chronic disorder and a major global health problem. Insulin resistance is the primary detectable abnormality and the main characteristic feature in individuals with type 2 DM.
Sónia Rocha +10 more
semanticscholar +1 more source
Fluorinated Pyrazoles: From Synthesis to Applications.
Chemical Reviews, 2020Fluorinated pyrazoles play an important role in medicinal chemistry, drug discovery, agrochemistry, coordination chemistry, and organometallic chemistry. Since the early 1990s, their popularity has grown exponentially.
Pavel K. Mykhailiuk
semanticscholar +1 more source
Organic Letters, 2021
Three types of trifluoromethylated pyrazolidines, pyrazolines, and pyrazoles can be synthesized via divergent reaction of β-CF3-1, 3-enyne with hydrazines. The reaction with simple hydrazine monohydrate or sulfonyl hydrazines as nucleophiles produces 1,3,
Lanlan Wei +4 more
semanticscholar +1 more source
Three types of trifluoromethylated pyrazolidines, pyrazolines, and pyrazoles can be synthesized via divergent reaction of β-CF3-1, 3-enyne with hydrazines. The reaction with simple hydrazine monohydrate or sulfonyl hydrazines as nucleophiles produces 1,3,
Lanlan Wei +4 more
semanticscholar +1 more source
Chinese Chemical Letters, 2021
A simple and efficient method for the synthesis of pyrazoles through a silicotungstic acid (H4SiW12O40)-catalyzed cyclization of epoxides/aldehydes and sulfonyl hydrazides has been developed. Various epoxides/aldehydes were smoothly reacted with sulfonyl
Guoping Yang +7 more
semanticscholar +1 more source
A simple and efficient method for the synthesis of pyrazoles through a silicotungstic acid (H4SiW12O40)-catalyzed cyclization of epoxides/aldehydes and sulfonyl hydrazides has been developed. Various epoxides/aldehydes were smoothly reacted with sulfonyl
Guoping Yang +7 more
semanticscholar +1 more source
Journal of Organic Chemistry, 2021
The cyclocondensation of cross-conjugated enynones, dienynones, and trienynones (easily available due to low-cost starting compounds) with arylhydrazines leads to the regioselective synthesis of pyrazole derivatives (dihetaryl-substituted ethens, buta-1 ...
A. Golovanov +5 more
semanticscholar +1 more source
The cyclocondensation of cross-conjugated enynones, dienynones, and trienynones (easily available due to low-cost starting compounds) with arylhydrazines leads to the regioselective synthesis of pyrazole derivatives (dihetaryl-substituted ethens, buta-1 ...
A. Golovanov +5 more
semanticscholar +1 more source
Synthesis of pyrazoles and condensed pyrazoles
Journal of Heterocyclic Chemistry, 1999AbstractThis review introduces the synthesis of various pyrazoles reported by us and some other research groups during 1989–1998. Some of papers in this review deal with the development of potent pyrazoles or with the synthesis of potential pyrazoles aiming at agrochemicals and/or drugs.
Kenzi Makino +2 more
openaire +1 more source