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Synthesis of Some Novel 2-{Pyrano[2,3-c]Pyrazoles-4-Ylidene}Malononitrile Fused with Pyrazole, Pyridine, Pyrimidine, Diazepine, Chromone, Pyrano[2,3-c]Pyrazole and Pyrano[2,3-d]Pyrimidine Systems as Anticancer Agents

Polycyclic aromatic compounds (Print), 2020
An unexpected efficient basic catalyzed heterocyclization reactions were carried out to build blocks of potentially bioactive 2-{pyrano[2,3-c]pyrazoles-4-ylidene}malononitrile skeleton fused with pyrazole, pyridine, pyrimidine, diazepine, chromone ...
D. Bakhotmah   +3 more
semanticscholar   +1 more source

Antibacterial and antifungal pyrazoles based on different construction strategies.

European journal of medicinal chemistry
The growing prevalence of microbial infections, and antimicrobial resistance (AMR) stemming from the overuse and misuse of antibiotics, call for novel therapeutic agents, particularly ones targeting resistant microbial strains. Scientists are striving to
M. Ur Rehman   +6 more
semanticscholar   +1 more source

Transition Metal‐free C−H Sulfonylation and Pyrazole Annulation Cascade for the Synthesis of 4‐Sulfonyl Pyrazoles

, 2020
A practical protocol for the synthesis of 4‐sulfonyl pyrazoles via the reactions of readily available N,N‐dimethyl enaminones and sulfonyl hydrazines has been developed via the catalysis of molecular iodine in the presence of TBHP and NaHCO3 at room ...
Lihong Tian, Jie-Ping Wan, Shou-Ri Sheng
semanticscholar   +1 more source

Pyrazoles. III. PMR studies of pyrazoles

Recueil des Travaux Chimiques des Pays-Bas, 1967
AbstractSubstituents with electron withdrawing capacities are found to induce a paramagnetic displacement of the chemical shifts of protons and methyl groups in the remaining positions of the pyrazole ring. For the 4‐position this effect is considered to be due primarily to resonance interaction of substituent and pyrazole ring.
Clarisse L. Habraken   +2 more
openaire   +1 more source

Synthesis and antibacterial evaluation of fused pyrazoles and Schiff bases

Synthetic Communications, 2018
For the discovery of new antibiotic drugs to face the problem of microbial resistance, a series of fused pyrazoles such as pyrazolopyrimidines 15a–f, pyrazoloquinazolines 18a, b and pyrazolotriazines 20a, b was synthesized via the reaction of 5 ...
A. Hassan   +4 more
semanticscholar   +1 more source

Diastereoselective synthesis and cytotoxic evaluation of new isoxazoles and pyrazoles with monoterpenic skeleton

, 2019
New series of chiral isoxazoles and pyrazoles with monoterpenic skeleton, have been efficiently synthesized from naturally occurring (R)-Carvone, using 1,3-dipolar cycloaddition reaction with arylonitrile oxides and diarylnitrilimines.
Ali Oubella   +8 more
semanticscholar   +1 more source

ChemInform Abstract: Synthesis of Pyrazoles and Condensed Pyrazoles

ChemInform, 1999
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Kenzi Makino   +2 more
openaire   +1 more source

Octahedral molybdenum iodide clusters with pyrazole or pyrazolate ligands

Dalton Transactions
Hexaaqua or hexahydroxo molybdenum iodide cluster complexes obtained in one step were shown to be accessible complexes for synthesis of clusters with pyrazole or pyrazolate ligands.
Ksenia S. Kozlova   +4 more
openaire   +2 more sources

Engineered Enzymes Enable Selective N-Alkylation of Pyrazoles With Simple Haloalkanes

Angewandte Chemie - International Edition, 2021
Bernhard Hauer   +2 more
exaly  

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