Results 131 to 140 of about 10,186 (207)
Exploring the Allosteric Pathways of Asciminib in the Dual Inhibition of BCR-ABL1. [PDF]
Ming J, Gao H, Zhan J.
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Organic Letters, 2021
A diethylzinc-promoted unconventional annulation reaction of 2,2,2-trifluorodiazoethane with 2H-azirines is described. This transformation involves two [3 + 2] cycloaddition steps and one dinitrogen extrusion process in one pot, thus giving a broad array
Yuefeng Chen +2 more
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A diethylzinc-promoted unconventional annulation reaction of 2,2,2-trifluorodiazoethane with 2H-azirines is described. This transformation involves two [3 + 2] cycloaddition steps and one dinitrogen extrusion process in one pot, thus giving a broad array
Yuefeng Chen +2 more
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Organic Letters, 2021
A TBAI/K2S2O8-promoted [4 + 2] annulation of ketene N,S-acetals, and N-tosylhydrazones was efficiently developed, enabling straightforward access to a variety of trisubstituted pyridazines in reasonable to good yields.
Zhuqing Liu, Jiang Lou, Jiaqi Xiao
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A TBAI/K2S2O8-promoted [4 + 2] annulation of ketene N,S-acetals, and N-tosylhydrazones was efficiently developed, enabling straightforward access to a variety of trisubstituted pyridazines in reasonable to good yields.
Zhuqing Liu, Jiang Lou, Jiaqi Xiao
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Chemistry - An Asian Journal, 2021
Acetylene surrogates are efficient tools in modern organic chemistry with largely unexplored potential in the construction of heterocyclic cores. Two novel synthetic paths to 3,6-disubstituted pyridazines were proposed using readily available acetylene ...
M. Ledovskaya +2 more
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Acetylene surrogates are efficient tools in modern organic chemistry with largely unexplored potential in the construction of heterocyclic cores. Two novel synthetic paths to 3,6-disubstituted pyridazines were proposed using readily available acetylene ...
M. Ledovskaya +2 more
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Journal of Molecular Structure, 2021
Pyridazine derivatives are a consequential class of heterocyclic compounds, which expose a wide range of distinguished biological activities. For example, pyridazine scaffolds are known as inhibitors of acetylcholinesterase (AChE), butyrylcholinesterase (
Hossein Mousavi
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Pyridazine derivatives are a consequential class of heterocyclic compounds, which expose a wide range of distinguished biological activities. For example, pyridazine scaffolds are known as inhibitors of acetylcholinesterase (AChE), butyrylcholinesterase (
Hossein Mousavi
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Chemistry and Biodiversity, 2020
A facile and convenient synthesis of new pyridazines suitable for use as antimicrobial agents was reported. The hydrazide intermediate was coupled with various benzaldehydes and/or acetophenones and cyclized instantaneously to afford target pyridazine ...
Muhamad Mustafa, Yaser A. Mostafa
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A facile and convenient synthesis of new pyridazines suitable for use as antimicrobial agents was reported. The hydrazide intermediate was coupled with various benzaldehydes and/or acetophenones and cyclized instantaneously to afford target pyridazine ...
Muhamad Mustafa, Yaser A. Mostafa
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ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
N. Haider, W. Holzer
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AbstractFor Abstract see ChemInform Abstract in Full Text.
N. Haider, W. Holzer
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Vibrational spectra of pyridazine, pyridazine-d4, pyridazine-3,6-d2 and pyridazine-4,5-d2
Spectrochimica Acta Part A: Molecular Spectroscopy, 1967Abstract Infrared spectra of the liquids pyridazine, pyridazine- d 4 and pyridazine-3,6- d 2 are reported from 270 to 4,000 cm −1 . Raman spectra are reported for these liquids with the state of polarization for many lines. The vibrational assignment suggested for these three compounds satisfies the three Teller—Redlich product rules within ...
H.D. Stidham, J.V. Tucci
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Bioorganic chemistry (Print), 2019
A new method of obtaining multifunctional pyrazoles by the reaction of 1,3-dipolar addition of tribenzylsulfonyliminochloride to polarophiles has been developed. This imine is obtained by reacting tribenzylamine with N-chlorobenzene sulfamide (chloramine-
G. Mamedova +10 more
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A new method of obtaining multifunctional pyrazoles by the reaction of 1,3-dipolar addition of tribenzylsulfonyliminochloride to polarophiles has been developed. This imine is obtained by reacting tribenzylamine with N-chlorobenzene sulfamide (chloramine-
G. Mamedova +10 more
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SYNTHESIS OF NEW PYRIDAZIN- 6-ONES, PYRIDAZIN-6-IMINES, 4-PYRIDAZINALS, AND PYRIDINES
Synthetic Communications, 2002ABSTRACT 3-Dimethyl-1-[3-methyl-(4H)-5-phenylimidazol[2,1-b]thiazol-2-yl]prop-2-enone 4 couples smoothly with benzenediazonium chloride to yield propanal 5 which is a key intermediate for the synthesis of pyridazinones 9–13, 16 and pyridazine-6-imine 8, 19.
Samia Sayed +3 more
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