Results 11 to 20 of about 148,723 (205)

Synthesis of Novel Structural Hybrids between Aza-Heterocycles and Azelaic Acid Moiety with a Specific Activity on Osteosarcoma Cells

Molecules, 2020
Nine compounds bearing pyridinyl (or piperidinyl, benzimidazolyl, benzotriazolyl) groups bound to an azelayl moiety through an amide bond were synthesized.
Gabriele Micheletti, Natalia Calonghi, Giovanna Farruggia, Elena Strocchi, Vincenzo Palmacci, Dario Telese, Silvia Bordoni, Giulia Frisco, Carla Boga   +8 more
doaj   +1 more source

Rhodococcus Strains from the Specialized Collection of Alkanotrophs for Biodegradation of Aromatic Compounds

Molecules, 2023
The ability to degrade aromatic hydrocarbons, including (i) benzene, toluene, o-xylene, naphthalene, anthracene, phenanthrene, benzo[a]anthracene, and benzo[a]pyrene; (ii) polar substituted derivatives of benzene, including phenol and aniline; (iii) N ...
Anastasiia Krivoruchko, Maria Kuyukina, Tatyana Peshkur, Colin J. Cunningham, Irina Ivshina   +4 more
doaj   +1 more source

(E)-1-(Pyridin-4-yl)propan-1-one oxime

IUCrData, 2016
The asymmetric unit of the title compound, C8H10N2O, contains two crystallographically independent molecules of slightly different conformation, which are linked via an intermolecular O—H...N hydrogen bond.
Michael Eitel, Dieter Schollmeyer, Pierre Koch   +2 more
doaj   +1 more source

3-Amino-6-ethoxy-4-phenyl-1H-pyrrolo[2,3-b]pyridine-2,5-dicarbonitrile

Molbank, 2010
(Z)-2-(4-Chloro-5H-1,2,3-dithiazol-5-ylideneamino)-6-ethoxy-4-phenylpyridine-3,5-dicarbonitrile 1, when treated with either triphenylphosphine (4 equiv.) or polymer bound triphenylphosphine (5 equiv.) in dichloromethane at room temperature for 3 days ...
Sophia S. Michaelidou, Panayiotis A. Koutentis   +1 more
doaj   +1 more source

Microwave-Assisted Synthesis, Structural Characterization and Assessment of the Antibacterial Activity of Some New Aminopyridine, Pyrrolidine, Piperidine and Morpholine Acetamides

Molecules, 2021
A series of new acetamide derivatives 22–28 of primary and secondary amines and para-toluene sulphinate sodium salt have been synthesized under microwave irradiation and assessed in vitro for their antibacterial activity against one Gram-positive and two
Abdulmajeed S. H. Alsamarrai, Saba S. Abdulghani   +1 more
doaj   +1 more source

5-[(3,5-Dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-1,3-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

Molbank, 2010
The title compound, 5-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-1,3-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione, has been synthesized by condensation of 1,3-diethyl-2-thiobarbituric acid and 3,5-dimethyl-1-phenylpyrazole-4-carbaldehyde in
Salman A. Khan, Abdullah Mohamed Asiri
doaj   +1 more source

Highly optical transparency and thermally stable polyimides containing pyridine and phenyl pendant

Designed Monomers and Polymers, 2017
In order to obtain highly optical transparency polyimides, two novel aromatic diamine monomers containing pyridine and kinky structures, 1,1-bis[4-(5-amino-2-pyridinoxy)phenyl]diphenylmethane (BAPDBP) and 1,1-bis[4-(5-amino-2-pyridinoxy)phenyl]-1 ...
Jianan Yao, Chunbo Wang, Chengshuo Tian, Xiaogang Zhao, Hongwei Zhou, Daming Wang, Chunhai Chen   +6 more
doaj   +1 more source

Crystal structures of N-(pyridin-2-ylmethyl)pyrazine-2-carboxamide (monoclinic polymorph) and N-(pyridin-4-ylmethyl)pyrazine-2-carboxamide

Acta Crystallographica Section E, 2014
The title compounds, C11H10N4O (HL1) and C11H10N4O (HL2), are pyridine 2-ylmethyl and 4-ylmethyl derivatives, respectively, of pyrazine-2-carboxamide. HL1 was measured at 153 K and crystallized in the monoclinic space group P21/c with Z = 4.
Dilovan S. Cati, Helen Stoeckli-Evans
doaj   +1 more source

Poly[[tetramethanolbis[4-oxo-3-(pyridin-4-yl)-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-olato]disodium]–diethyl ether–methanol (1/1/2)]

IUCrData, 2016
In the title compound, [Na2(C16H7Cl3N5O2)2(CH3OH)4]·C4H10O·2CH3OH, the central pyrazolo[3,4-d]pyrimidine system makes dihedral angles of 82.98 (7)° with the trichlorophenyl ring and 13.11 (15)° with the pyridine ring.
Bassam Abu Thaher, Dieter Schollmeyer, Stefan Laufer   +2 more
doaj   +1 more source

Discovery of novel isonipecotic acid-based heteroaryl amino acid derivatives as potential anticonvulsant agents: Design, synthesis, in-silico ADME study, and molecular docking studies

Journal of Pharmacy and Bioallied Sciences, 2023
Background: Epilepsy is a neurological disorder characterized by anomalous brain activity, convulsions, and odd behavior. Several substituted-(naphthalen-2-yl)-3-(1H-indol-3-yl) allyl)-1,4-dihydropyridine-4-carboxylic acid derivatives (5a-j) were ...
Mohammad M Ahmad, Naseem Akhtar, Shamshir Khan, Mohd Rashid, Md Tanwir Athar, Zabih Ullah, Mohamad Taleuzzaman   +6 more
doaj   +1 more source