Results 31 to 40 of about 344,103 (291)

Redetermination of para-aminopyridine (fampridine, EL-970) at 150 K [PDF]

, 2005
The structure of fampridine (EL-970) or 4-aminopyridine, C₅H₆N₂, has been redetermined at 150 K. The room-temperature structure has been reported previously [Chao & Schempp (1977). Acta Cryst. B33, 1557-1564]. Pyramidalization at the amine N atom occurs
Anderson, Frankie P., Gallagher, John F., Kenny, Peter T.M., Lough, Alan J.   +3 more
core   +1 more source

Poly[[tetramethanolbis[4-oxo-3-(pyridin-4-yl)-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-olato]disodium]–diethyl ether–methanol (1/1/2)]

IUCrData, 2016
In the title compound, [Na2(C16H7Cl3N5O2)2(CH3OH)4]·C4H10O·2CH3OH, the central pyrazolo[3,4-d]pyrimidine system makes dihedral angles of 82.98 (7)° with the trichlorophenyl ring and 13.11 (15)° with the pyridine ring.
Bassam Abu Thaher, Dieter Schollmeyer, Stefan Laufer   +2 more
doaj   +1 more source

Discovery of novel isonipecotic acid-based heteroaryl amino acid derivatives as potential anticonvulsant agents: Design, synthesis, in-silico ADME study, and molecular docking studies

Journal of Pharmacy and Bioallied Sciences, 2023
Background: Epilepsy is a neurological disorder characterized by anomalous brain activity, convulsions, and odd behavior. Several substituted-(naphthalen-2-yl)-3-(1H-indol-3-yl) allyl)-1,4-dihydropyridine-4-carboxylic acid derivatives (5a-j) were ...
Mohammad M Ahmad, Naseem Akhtar, Shamshir Khan, Mohd Rashid, Md Tanwir Athar, Zabih Ullah, Mohamad Taleuzzaman   +6 more
doaj   +1 more source

Degradation of pyridine in coal chemical wastewater using ionizing radiation and synergistic processes

Fushe yanjiu yu fushe gongyi xuebao
This study investigates the degradation of pyridine in coal chemical wastewater using electron beam (EB) irradiation and explores the impacts of absorbed dose, initial pyridine concentration, and pH.
WANG Xinxuan, YANG Qi, ZHANG Zhonglei, CHEN Hai, CHEN Chuanhong, ZHANG Tao   +5 more
doaj   +1 more source

Concentration dependent tautomerism in green [Cu(HL1)(L2)] and brown [Cu(L1)(HL2)] with H2L1 = (E)-N’-(2-hydroxy-3-methoxybenzylidene)- benzoylhydrazone and HL2 = pyridine-4-carboxylic (isonicotinic) acid [PDF]

, 2011
The in situ formed hydrazone Schiff base ligand (E)-N’-(2-hydroxy-3-methoxybenzylidene)-benzoylhydrazone (H2L1) reacts with copper(II) acetate in ethanol in the presence of pyridine-4-carboxylic acid (isonicotinic acid, HL2) to green-[Cu(HL1)(L2)]・H2O ...
Ghorbanloo, Massomeh, Hosseini Monfared, Hassan, Janiak, Christoph, Mahdavi Yeganeh, Mahdi, Mayer, Peter, Vahedpour, Morteza   +5 more
core   +1 more source

An Efficient Synthesis of a Variety of Substituted Pyridine-3-Thiols

Журнал органічної та фармацевтичної хімії
A practical and convenient method for the synthesis of pyridine-3-thiols using substituted 3-iodopyridines as starting compounds has been developed. Based on the use of thiobenzoic acid as a sulfur donor in a two-step procedure, this approach made it ...
Oleksandr V. Borysov, Dmytro P. Bohdan
doaj   +1 more source

Scope and Limitations of a Novel Synthesis of 3-Arylazonicotinates

Molecules, 2012
The reaction of 3-oxo-3-phenyl-2-phenylhydrazonal with functionally substituted and heteroaromatic substituted acetonitrile to yield arylazonicotinic acid derivatives and 5-arylsubstituted pyridines was established. In some cases the produced nicotinates
Awatef Mohamed El-Maghraby, Maghraby Ali Selim, Omniya Sayed Zaky, Moustafa Sherief Moustafa, Mohamed Hilmy Elnagdi   +4 more
doaj   +1 more source

5,5'-(1,4-Phenylenedimethylylidene)bis(1,3-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione)

Molbank, 2010
A novel compound, 5,5'-(1,4-phenylenedimethylylidene)bis(1,3-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione) (3) has been synthesized by condensation of 1,3-diethyl-2-thiobarbituric acid and terephthalaldehyde in anhydrous ethanol in the presence of ...
Salman A. Khan, Abdullah Mohamed Asiri
doaj   +1 more source

Synthesis and late-stage functionalization of complex molecules through C-H fluorination and nucleophilic aromatic substitution. [PDF]

, 2014
We report the late-stage functionalization of multisubstituted pyridines and diazines at the position α to nitrogen. By this process, a series of functional groups and substituents bound to the ring through nitrogen, oxygen, sulfur, or carbon are ...
Fier, Patrick S, Hartwig, John F
core   +3 more sources

Synthesis, Crystallographic Study and Antibacterial Activity of Ternary Copper(II) Complex with Chromone-Based Ligand and Pyridine

Crystals
A new copper(II) complex was synthesized using chromone-2-carboxylic acid as the main ligand, and coordinated pyridine molecules. The complex was successfully crystallized and structurally characterized by single crystal X-ray diffraction.
Nikolina Filipović, Anamarija Stanković, Martina Medvidović-Kosanović, Dominik Goman, Stjepan Šarić, Goran Palijan, Tomislav Balić   +6 more
doaj   +1 more source