Results 161 to 170 of about 1,014,531 (338)

Phenyl and Benzyl Azido Carboxylic Acids: Exploring the Organic Azide Alongside the Carboxylic Acid–Pyridine Supramolecular Synthon

Organic azides are widely used in synthetic organic chemistry but remain comparatively rare in crystal engineering. This work leverages the carboxylic acid–pyridine (CA–Py) supramolecular synthon to systematically evaluate if and how an organic azide may
Orion B. Berryman, Stefan Peintner, Michael Jahnke, Daniel A. Decato   +3 more
core   +1 more source

Design, synthesis and activity evaluation of tetrahydroisoquinoline‐based programmed cell death ligand 1 inhibitors

Smart Molecules, EarlyView.
Based on a 3D‐quantitative structure‐activity relationship pharmacophore model, structural optimization of Y6 yielded Y7f. Mechanistic studies revealed that Y7f acted as a programmed death receptor 1/programmed cell death ligand 1 (PD‐L1) interaction inhibitor by inducing PD‐L1 dimerization. Y7f restored T‐cell function.
Menglin Yu, Sen Cai, Yanyan Pan, Heshuang Wang, Fengwu Zhang, Aiyu Ma, Shixuan Lv, Xiuhan Guo, Shisheng Wang, Qiling Song, Chunyan Ma, Shuai Wang, Li Zhang, Jian Wang, Qingwei Meng, Yueqing Li   +15 more
wiley   +1 more source

Enhanced Solubility of Famotidine through Salification. [PDF]

Cryst Growth Des
Eilers JM, Seo P, Ma L, Kelley SP, Hutchins KM.   +4 more
europepmc   +1 more source

Determination of Masked Basicity in Imidazo[1,5-a]pyridine Carboxylic Acids Using Esters

Svitlana V. Stetsenko, Galyna P. Grabchuk   +1 more
openalex   +1 more source

Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds

The Chemical Record, EarlyView.
This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá, Patrick C. Nobre, Isabelly O. Ferreira, Juliano B. Azeredo, Vanessa Nascimento   +4 more
wiley   +1 more source

Pyridine-4-Carboxylic Acid-Assisted Fabrication of an Anisotropic Ag Nanodendrites-Modified Glassy Carbon Electrode for the Differential Pulse Anodic Stripping Voltammetry (DPASV) Determination of Cadmium(II) and Lead(II)

Junrong Chen, Zhenzhen Zhang, Jinhua Zhou, Tianjing Zeng, Hongbo Xiao, Ting Yang, Tao Xu, Lizhi Wang, Wenlei Wang   +8 more
openalex   +1 more source

Determination of Lead Ion in the Presence of Pyridine-3-Carboxylic Acid Using Square Wave Voltammetry

, 2021
Mohammed Zidan, NurulHudahbt Rahman, Nouria Ali BELKHER   +2 more
openalex   +2 more sources

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

The Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra, Subba Rao Cheekatla, Keshaba Nanda Parida   +2 more
wiley   +1 more source

Decarboxylative functionalization strategy for rapid assembly of bifunctional adamantane <i>meta</i>-arene bioisosteres. [PDF]

Chem Sci
MacAllister CA, Solis OA, Reif AJ, Goodwin NC, Yoon TP.   +4 more
europepmc   +1 more source

The different 6-substituent on 5-bromo-pyridine-2-carboxylic acid skeleton induced the fabrication of five diverse copper(II) complexes: the synthesis, structural comparison, Hirshfeld surface analysis and magnetic properties

Jun‐Xia Li, Ya-Ni Ding, Xin Li, Yang-Yang Gu, Xun Feng   +4 more
openalex   +1 more source