Results 181 to 190 of about 1,014,531 (338)
Structural and biochemical basis for retinol‐binding protein 4 antagonism by tinlarebant
Background and Purpose Retinol‐binding protein 4 (RBP4) is a member of the lipocalin superfamily that is connected to disease states such as insulin resistance, fatty liver disease and ocular disorders including Stargardt disease. Several retinoid and non‐retinoid antagonists of this protein have been developed for potential clinical use, but none have
Marco Bassetto, Philip D. Kiser
wiley +1 more source
Direct Conversion of Methyl-Ethyl-Ketone into Olefins Precursors of Fuels and Chemicals over Supported Cu Catalysts. [PDF]
Shi H, He Y, Dagle VL.
europepmc +1 more source
ABSTRACT Nitro‐fatty acids (NO2‐FAs) are potent electrophiles that react with nucleophilic residues in proteins (cysteines, histidines and lysines) via a process known as nitroalkylation. This reversible post‐translational modification (PTM) functions as a selective signalling mechanism by modulating the structure, transport, and catalysis of target ...
Lorena Aranda‐Caño +9 more
wiley +1 more source
Molecular Recognition and Chirality Sensing with Metallocene Dichloride Complexes. [PDF]
Kim Y, Formen JSSK, Wolf C.
europepmc +1 more source
Surface ligands govern quantum dot photocatalysis through thermodynamic band‐edge tuning, kinetic charge‐transfer regulation, and microenvironmental control. Rational ligand engineering, using short‐chain, inorganic, conjugated, or dual‐ligand systems, enables efficient solar fuel production, selective organic transformations, environmental remediation,
Yali Weng +5 more
wiley +1 more source
Electrochemical α-acyloxylation of dibenzoylmethane with C-terminal carboxylic acids for peptide and drug diversification. [PDF]
Jiang S +6 more
europepmc +1 more source
Development of Radioiodinated Tetrahydropyrazolopyridine Inhibitors Targeting mIDH
Iodinated tetrahydropyrazolopyridine ligands show enhanced potency and selectivity for mutant IDH1 compared with their fluorinated counterparts and can be efficiently radiolabeled with I‐125, supporting the basis for further evaluation as mIDH1‐targeting radiotheranostic candidates.
Sarandeep Kaur +7 more
wiley +1 more source
Thiolane sulfoximines provide practical and safer surrogates for hazardous azides in nitrene photochemistry, enabling direct access to 7,8‐diaminoquinolines and fused δ‐lactams. DFT calculations support the reaction mechanism and rationalize product selectivity.
Lorenzo Serusi +5 more
wiley +1 more source
Co-crystallisation of pyridine with terephthalic, trimesic, phthalic, isophthalic and pyromellitic acids has been investigated via single crystal X-ray diffraction and thermogravimetric analysis, concentrating on the nature of the intermolecular ...
Dale SH +3 more
core +2 more sources

