Results 201 to 210 of about 1,014,531 (338)
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disease, and cholinergic dysfunction is considered one of the fundamental pathological factors of this disease. Guided by the clinically used acetylcholinesterase (AChE) inhibitor donepezil, we explored trimetazidine dihydrochloride as an accessible starting scaffold to generate ...
Muhammed Oğuzhan Doğan +6 more
wiley +1 more source
Ketone homologation via palladium-catalysed decarboxylative rearrangement. [PDF]
Gong J, Wang Q, Zhu J.
europepmc +1 more source
ABSTRACT The separation of light olefins is a crucial process in the petrochemical industry, and developing advanced adsorbent materials is very significant. Aluminum (Al) cluster‐based heterometallic frameworks possess great application prospects but have rarely been investigated for separation applications.
Song‐Yan Sui +4 more
wiley +1 more source
Carbon Quaternization at the α-Position of Thiazoles: Iron-Catalyzed Hydroheteroarylation Using Unactivated Alkenes. [PDF]
Lee J +7 more
europepmc +1 more source
Substituent‐Guided Routing in Chemical Reaction Networks
Substituents act as molecular traffic directors, routing EDC‐fueled oligoesterification either into a constrained reversible dimer loop or through an interconnected, scrambling‐enabled network of higher oligomers. ABSTRACT Metabolism is a complex chemical reaction network (CRN) that distributes reaction flux across multiple pathways, and mimicking such
Yeonsoo Lim +7 more
wiley +1 more source
Direct Access to Chiral Piperidines by Enantioselective HAT‐Initiated C(sp3)─H Oxidation
The direct desymmetrization of piperidines is achieved through manganese‐catalyzed enantioselective α‐C(sp3)─H oxidation with hydrogen peroxide, affording versatile chiral N,O‐acetals in good yields and with high enantio‐ and diastereoselectivity. These intermediates provide access to diverse functionalized piperidines with retention of chirality ...
Sethuraman Muthuramalingam +5 more
wiley +2 more sources
A quarter-century journey into 4-chromone derivatives: synthesis, reactions, and pioneering applications thereof. [PDF]
Ashraf El-Awady A +3 more
europepmc +1 more source
Structural characteristic of pyridine carboxylic acid adducts with squaric acid
Gołdyn, Mateusz
openalex +1 more source
Upcycling Industrial Lignin Into Cationic Hydrogels With Potential for Sustainable Plant Protection
Industrial lignin is upcycled into cationic lignin (CL) and embedded within chitosan–genipin (CH–GPN) hydrogels to form bioactive hydrogel networks with potential for antimicrobial plant protection. The CL‐embedded CH–GPN hydrogels retain porous, gel‐like properties and show enhanced in vitro inhibition of the plant pathogen Pseudomonas syringae.
Darindra Sandya Thanos +7 more
wiley +1 more source

