Results 201 to 210 of about 1,014,531 (338)

Design, Synthesis and Molecular Docking Studies of Some Novel Hydrazone Derivatives Based on Trimetazidine as Selective and Potent AChE Inhibitors

open access: yesDrug Development Research, Volume 87, Issue 7, November 2026.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disease, and cholinergic dysfunction is considered one of the fundamental pathological factors of this disease. Guided by the clinically used acetylcholinesterase (AChE) inhibitor donepezil, we explored trimetazidine dihydrochloride as an accessible starting scaffold to generate ...
Muhammed Oğuzhan Doğan   +6 more
wiley   +1 more source

A Cluster‐to‐Cluster Direct‐Linked Al8‐Cd Heterometallic MOF: Construction and Efficient C3H6/C2H4 Separation Performance

open access: yesRare Metals, Volume 45, Issue 11, November 2026.
ABSTRACT The separation of light olefins is a crucial process in the petrochemical industry, and developing advanced adsorbent materials is very significant. Aluminum (Al) cluster‐based heterometallic frameworks possess great application prospects but have rarely been investigated for separation applications.
Song‐Yan Sui   +4 more
wiley   +1 more source

Substituent‐Guided Routing in Chemical Reaction Networks

open access: yesChemSystemsChem, Volume 8, Issue 6, November 2026.
Substituents act as molecular traffic directors, routing EDC‐fueled oligoesterification either into a constrained reversible dimer loop or through an interconnected, scrambling‐enabled network of higher oligomers. ABSTRACT Metabolism is a complex chemical reaction network (CRN) that distributes reaction flux across multiple pathways, and mimicking such
Yeonsoo Lim   +7 more
wiley   +1 more source

Direct Access to Chiral Piperidines by Enantioselective HAT‐Initiated C(sp3)─H Oxidation

open access: yesAngewandte Chemie, Volume 138, Issue 44, 26 October 2026.
The direct desymmetrization of piperidines is achieved through manganese‐catalyzed enantioselective α‐C(sp3)─H oxidation with hydrogen peroxide, affording versatile chiral N,O‐acetals in good yields and with high enantio‐ and diastereoselectivity. These intermediates provide access to diverse functionalized piperidines with retention of chirality ...
Sethuraman Muthuramalingam   +5 more
wiley   +2 more sources

Upcycling Industrial Lignin Into Cationic Hydrogels With Potential for Sustainable Plant Protection

open access: yesChemSusChem, Volume 19, Issue 20, 28 October 2026.
Industrial lignin is upcycled into cationic lignin (CL) and embedded within chitosan–genipin (CH–GPN) hydrogels to form bioactive hydrogel networks with potential for antimicrobial plant protection. The CL‐embedded CH–GPN hydrogels retain porous, gel‐like properties and show enhanced in vitro inhibition of the plant pathogen Pseudomonas syringae.
Darindra Sandya Thanos   +7 more
wiley   +1 more source

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