The convergent total synthesis of a candidate diastereomer of amphirionin‐5 was accomplished in 22 steps via the coupling of the C1‐C16 enone segment and the C17‐C28 aldehyde segment using Stetter reaction. The overall stereochemistry of amphirionin‐5 was fully assigned, based on the comparison of spectroscopic and chiroptical data between the ...
Yusuke Ogura +7 more
wiley +1 more source
The dynamic chemistry of the boron-nitrogen bond. [PDF]
Frateloreto F +6 more
europepmc +1 more source
The cis‐2,3‐bis(trifluoromethyl)cyclopropyl chemotype is introduced. The steric demand of this motif is intermediate between that of the heptafluoroisopropyl and prefluorotertbutyl groups; yet, it induces significantly less lipophilicity than these due to its facial polarity.
Daniel Gaviña +5 more
wiley +1 more source
Trifluoromethylation of alkyl electrophiles with <sup>11</sup>C- or <sup>18</sup>F-labeled fluoroform for PET applications. [PDF]
Wang C +5 more
europepmc +1 more source
In this work, 1,4‐benzodiazepine‐2‐ones are synthesized starting from Kobayashi‐type aryne precursors and amino acid‐derived, unsymmetrical imides. Operationally simple protocols to access both the starting materials and the potential active pharmaceutical ingredients are presented.
Jasper Mindner +5 more
wiley +1 more source
Metabolomic Profile of Açai (<i>Euterpe oleracea</i> Mart., <i>Euterpe precatoria</i> Mart.), Mirití (<i>Mauritia flexuosa</i> L.), and Cupuassu (<i>Theobroma grandiflorum</i> (Wild. ex Spreng.) Schum) from Colombian Amazon: Insights into Nutritional Composition and Ripening Dynamics. [PDF]
Rodríguez MS +6 more
europepmc +1 more source
Sulfoethylated and carboxyethylated lignin derivatives were fabricated, and their impacts on stabilizing soybean oil–water were analyzed in Pickering and non‐Pickering systems. It was noticed that the lignin derivatives behaved very differently, implying that the modification routes played an important role in their performance.
Saba Khodavandegar +4 more
wiley +1 more source
Recent advances in glutarimide chemistry for cereblon-mediated targeted protein degradation: developments in synthesis and diversification. [PDF]
Ba X +3 more
europepmc +1 more source
This review explores recent progress in graphene‐based polymeric nanocomposite hydrogels and how they enhance mechanical strength, electrical conductivity, and biocompatibility. It outlines key fabrication strategies and highlights applications in drug delivery, tissue engineering, and photothermal therapy, while also discussing the emerging role of ...
Abrar Hussain +7 more
wiley +1 more source
Biosynthesis and characterization of zinc oxide nanoparticles using Dennettia tripetala for the antioxidant and drug release potentials. [PDF]
Oluwaniyi O, Oyewo B.
europepmc +1 more source

