Results 261 to 270 of about 1,014,531 (338)
Control of Gemcitabine Activity With Blue and Red Light
Treating cancer with chemotherapy is generally associated with many side effects, which can be addressed by selectively releasing the desired drugs with visible light. Sixteen new blue light‐activatable cytostatics were introduced, with the gemcitabine derivative exhibiting ideal properties.
Nils F. Kersten +6 more
wiley +1 more source
Trends towards multidrug-resistant bacteria: heterocyclic compounds containing antimicrobial agents: review. [PDF]
Mohamed FAM +3 more
europepmc +1 more source
Conversion of Alcohols to Alkyl Chlorides Using the Bichloride Ionic Liquid [NEt3Me][Cl(HCl)n]
The ionic liquid [NEt3Me][Cl(HCl)1.61] is presented as a controllable source of HCl for the effective transformation of a broad range of alcohols into alkyl chlorides. The process eliminates the need for continuous handling of HCl gas and enables a recyclable IL‐based catalyst system. The solvent‐free chlorination of alcohols using the bichloride‐based
Justus H. Peter +8 more
wiley +1 more source
Flavin Catalysts in Organic Synthesis
Flavins and their congeners are potent catalysts for organic synthesis inspired by enzymatic transformations. In addition to catalysis in the flavin ground state via covalent intermediates, the excited singlet and triplet states unlock applications including photooxidation, photoreduction, and energy transfer via sensitization.
Jan Freudenberg, Golo Storch
wiley +2 more sources
Design, synthesis, molecular docking and anticancer activity of novel <i>N</i>-(4-(chlorodifluoromethoxy)phenyl)-1<i>H</i>-pyrrolo[2,3-<i>b</i>]pyridine-5-carboxamide derivatives. [PDF]
Bhise PB +10 more
europepmc +1 more source
The Expanding Role of Diazirines in Synthetic Methodology
Beyond their established role in photoaffinity labeling, diazirines have emerged as versatile reagents in synthetic chemistry. This review highlights their dual reactivity as carbene and nitrogen‐transfer precursors, showcasing mechanistic insights and diverse applications in cyclopropanations, cycloadditions, skeletal editing, amination, heterocycle ...
Viktor Savic +3 more
wiley +1 more source
A practical strategy for synthesizing β‐ and γ‐carbolinones from indole‐based Ugi 4‐CR adducts through an intramolecular radical cyclization using Fe(III)–H species is presented. This approach enables the efficient synthesis of spiro‐carbolinones under mild reaction conditions and demonstrates the effectiveness of secondary radicals in both cyclization
María F. Olvera‐Granados +1 more
wiley +1 more source
Positional isomerization of pyridine through nitrogen transposition. [PDF]
Choi W, Ju H, Park J, Hong S.
europepmc +1 more source
Design, synthesis and antifungal activity of pyrazole ester derivatives. [PDF]
Shen Y +4 more
europepmc +1 more source

