Results 51 to 60 of about 1,014,531 (338)

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

Advanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang, Mengqian Xu, Huaping Zhao, Yulin Xie, Guoqing Zhu, Haoze Li, Qianqian Sun, Yong Lei, Chunxia Li   +8 more
wiley   +1 more source

High Temperature and Organosoluble Poly(amide-imide)s Based on 1,4-Bis[4-aminophenoxy]butane and Aromatic Diacids by Direct Polycondensation: Synthesis and Properties

High Temperature Materials and Processes, 2013
A series of high temperature and organosoluble poly(amide-imide)s 8a–g were prepared by direct polycondensation from 1,4-bis[4-aminophenoxy]butane 4 and various aromatic diacids 7a–g in a medium consisting of N-methyl-2-pyrrolidone (NMP)/triphenyl ...
Faghihi Khalil, Ashouri Mostafa, Hajibeygi Mohsen   +2 more
doaj   +1 more source

The synthesis and biological assessment of [[1,2,4]triazolo[4,3-a]pyridine-3-yl]acetamides with an 1,2,4-oxadiazol cycle in positions 6, 7 and 8

Журнал органічної та фармацевтичної хімії, 2019
Fused heterocyclic 1,2,4-triazoles have provided much attention due to variety of their interesting biological properties. Aim. To develop the method for the synthesis of novel 2-[(1,2,4-oxadiazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridine-3-yl]acetamides and
V. R. Karpina, S. S. Kovalenko, S. M. Kovalenko, O. V. Zaremba, O. V. Silin, T. Langer   +5 more
doaj   +1 more source

Nickel(II) and copper(II) complexes of some pyridinecarboxylic acids

, 1974
Complexes of nickel(11) and copper(11) with the ligands 6-methylpyridine-2-carboxylic, pyridine-2- carboxylic and pyridine-3-carboxylic acids have been prepared from non-aqueous media.
EC Watton, RS Vagg, VM Ellis
core   +1 more source

A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau

Advanced Science, EarlyView.
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun, Yang Liu, Qiuzhi Zhou, Qingyuan Hu, Weixia Wang, Yue Xiao, Jingfen Su, Guanting Liu, Miaomiao Sun, Lixia Chen, Hua Li, Ying Yang, Jian‐Zhi Wang   +12 more
wiley   +1 more source

Macrocyclization of ω‐Isocyano Aldehydes

Angewandte Chemie, EarlyView.
The ω‐isocyano aldehydes readily undergo cyclization to afford α‐acyloxy, α‐hydroxy, α‐acetamido, and α‐keto macrolactams, as well as tetrazole‐fused macrocycles, via C(sp3)─C(sp2) bond formation, providing access to diverse α‐functionalized medium‐sized lactams and macrolactams. ABSTRACT Medium‐sized rings and macrocycles constitute a privileged class
Baochao Yang, Teerawat Songsichan, Cyril Piemontesi, Qian Wang, Jieping Zhu   +4 more
wiley   +2 more sources

Heteroatom‐Mediated Covalent Organic Framework Membranes With Nitrogen‐Enriched Nanochannels for Efficient Desalination

Advanced Science, EarlyView.
Heteroatom precursor engineering serves as a molecular‐level strategy to tailor hydrazide monomer reactivity and diffusion kinetics, enabling controlled assembly of highly crystalline COF membranes with ultramicroporous channels. The nitrogen‐enriched nanochannels deliver high water/ion selectivity via simultaneous water transport acceleration and ion ...
Guishan Hu, Muning Chen, Yunqiu Zhou, Yu Zhen, Miaomiao Tian, Yatao Zhang, Jingwei Hou, Junyong Zhu, Yong Wang   +8 more
wiley   +1 more source

Electronic Nose and Gas Chromatograph Devices for the Evaluation of the Sensory Quality of Green Coffee Beans

Foods, 2023
The aim of this work is to discriminate between the volatile org9anic compound (VOC) characteristics of different qualities of green coffee beans (Coffea arabica) using two analysis approaches to classify the fresh product.
Gema Cascos, Jesús Lozano, Ismael Montero-Fernández, Jhunior Abrahan Marcía-Fuentes, Ricardo S. Aleman, Antonio Ruiz-Canales, Daniel Martín-Vertedor   +6 more
doaj   +1 more source

Chemical Characterization of Polar Species in Colombian Vacuum Residue and Its Supercritical Fluid Extraction Subfractions Using Electrospray Ionization FT-ICR Mass Spectrometry

Chemical Engineering Transactions, 2017
Compositional changes of Colombian vacuum residue and its supercritical fluid extraction fractionation (SFEF) subfractions were analysed by positive- and negative mode electrospray (ESI) coupled with Fourier-transform ion cyclotron resonance mass ...
J.P. Arenas-Diaz, D.C. Palacio Lozano, X. Ramirez, R. Cabanzo, A. Guzman, E. Mejia-Ospino   +5 more
doaj   +1 more source

Pyridine Carboxamides Based on Sulfobetaines: Design, Reactivity, and Biological Activity

Molecules, 2022
The synthesis of the products of the 1,3-propanesultone ring opening during its interaction with amides of pyridinecarboxylic acids has been carried out.
Eugene P. Kramarova, Sophia S. Borisevich, Edward M. Khamitov, Alexander A. Korlyukov, Pavel V. Dorovatovskii, Anastasia D. Shagina, Konstantin S. Mineev, Dmitri V. Tarasenko, Roman A. Novikov, Alexey A. Lagunin, Ivan Boldyrev, Aiarpi A. Ezdoglian, Natalia Yu. Karpechenko, Tatiana A. Shmigol, Yuri I. Baukov, Vadim V. Negrebetsky   +15 more
doaj   +1 more source