Results 31 to 40 of about 1,014,531 (338)

Recurrence of carboxylic acid-pyridine supramolecular synthon in the crystal structures of some pyrazinecarboxylic acids

, 2001
X-ray crystal structures of pyrazinic acid 1 and isomeric methylpyrazine carboxylic acids 2-4 are analyzed to examine the occurrence of carboxylic acid-pyridine supramolecular synthon V in these heterocyclic acids. Synthon V, assembled by (carboxyl)O-H···
Vishweshwar, Peddy, Lynch, Vincent M., Nangia, Ashwini, Ashwini Nangia, Vincent M. Lynch, Peddy Vishweshwar   +5 more
core   +1 more source

Recurrence of Carboxylic Acid−Pyridine Supramolecular Synthon in the Crystal Structures of Some Pyrazinecarboxylic Acids

, 2016
X-ray crystal structures of pyrazinic acid 1 and isomeric methylpyrazine carboxylic acids 2−4 are analyzed to examine the occurrence of carboxylic acid−pyridine supramolecular synthon V in these heterocyclic acids. Synthon V, assembled by (carboxyl)O−H···
Ashwini Nangia (1400761), Peddy Vishweshwar (2394661), Vincent M. Lynch (1578592)   +2 more
core   +1 more source

Magnetic amine-functionalized graphene oxide as a novel and recyclable bifunctional nanocatalyst for solvent-free synthesis of pyrano[3,2-c]pyridine derivatives [PDF]

Nanochemistry Research, 2017
The new magnetic amine-functionalized graphene oxide (Fe3O4-GO-NH2) nanocatalyst was prepared through the reaction of 3-aminopropyltriethoxysilane (APTES) with magnetic graphene oxide (Fe3O4-GO).
Shahnaz Rostamizadeh, Asieh Hemmasi, Negar Zekri   +2 more
doaj   +1 more source

2-Bromopyridine-3-carboxylic acid [PDF]

Acta Crystallographica Section E Structure Reports Online, 2010
Le résidu d'acide carboxylique dans le composé du titre, C(6)H(4) BrNO (2), est tordu hors du plan des autres atomes, comme indiqué par l'angle de torsion (Br) C-C-C-O (carbonyl) de -20,1 (9)°. Dans le cristal, des chaînes supra-moléculaires médiées par des liaisons hydrogène O-H ?N sont formées avec le vecteur de base [201] et les interactions C-H ?O ...
R.A. Howie, Rinaldo Gonçalves, M.V.N. De Souza, Edward R. T. Tiekink, J.L. Wardell   +4 more
openaire   +3 more sources

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Enhancing Reaction Kinetics and Structural Control in N‐Carboxyanhydride (NCA) Polypeptide Synthesis by Structurally Tuned Azamacrocyclic Ligands

Angewandte Chemie, EarlyView.
Azamacrocycles provide a tunable platform for rapid N‐carboxyanhydride (NCA) Ring‐Opening Polymerization (ROP). Changing the methylation pattern switches the macrocycle from an external catalyst (N14Me3) to a covalent initiator‐catalyst (IniCat, N14Me1), delivering controlled polypeptide growth under open‐vessel conditions.
Paulina Maksym, Adam Gorczynski, Robert D. Murphy, Gianluca Bartolini Torres, Roksana Wygoda, Karol Garbaczewski, Giuseppe Forte, Giuseppe Consiglio, Yixuan Chen, Sébastien Perrier, Andreas Heise   +10 more
wiley   +2 more sources

Lewis Acid Site Engineering in MOF‐Derived Aluminum Oxide/Carbon Composites for Dechlorination of Waste Plastic Pyrolysis Oil

Advanced Functional Materials, EarlyView.
Controlled carbonization of an Al‐MOF partially decomposes its linkers, exposing coordinatively unsaturated Al centers within an oxide/carbon composite. The resulting Lewis acid sites, rather than surface area, govern organochlorine capture: the composite removes chemically diverse organochlorines from waste plastic pyrolysis oil, outperforms a ...
Seong Cheon Kim, Byeongju Jeon, Suk Hyun Lim, Eun Hee Kwon, Nam Sun Nho, Siyoung Q. Choi, Jeasung Park   +6 more
wiley   +1 more source

Investigation of Pyridine Carboxylic Acids in CM2 Carbonaceous Chondrites: Potential Precursor Molecules for Ancient Coenzymes [PDF]

, 2014
The distribution and abundances of pyridine carboxylic acids (including nicotinic acid) in eight CM2 carbonaceous chondrites (ALH 85013, DOM 03183, DOM 08003, EET 96016, LAP 02333, LAP 02336, LEW 85311, and WIS 91600) were investigated by liquid ...
House, Christopher H., Gerakines, Perry A., Callahan, Michael P., Dworkin, Jason P., Smith, Karen E.   +4 more
core   +2 more sources

Breakthrough Design of Highly Potent Antivirals Against Wild‐Type HIV‐1 and Lenacapavir‐Resistant M66I Variant

Angewandte Chemie, EarlyView.
Lenacapavir, the first‐in‐class drug targeting HIV‐1 capsid, is a breakthrough drug in HIV‐1 treatment and prophylaxis. However, a single M66I mutation confers complete viral resistance to lenacapavir. We report herein the design and synthesis of innovative R2 analogs demonstrating low nM potency against HIV‐1 M66I and excellent pharmacokinetics in ...
Nicolas Jamey, D. M. Nirosh Udayanga, Huanchun Zhang, Roshan Katekar, Wei Xie, Shreya M. Ravichandran, Xinyong Cai, Zachary C. Lorson, William M. McFadden, Won Hee Ryu, Jiashu Xie, Karen A. Kirby, Stefan G. Sarafianos, Zhengqiang Wang   +13 more
wiley   +2 more sources

Thermal and mesomorphic behavior of hydrogen-bonded liquid crystals of new pyridine derivatives

Discover Applied Sciences
The fascinating supramolecular structures formed through intermolecular hydrogen bonding (HB) interactions have gained importance in materials and biological science research.
Suma Ramachandra Gopady, V. N. Vijayakumar, Raviraj Shetty, Mallikarjun Bhavanari, Srinivasulu Maddasani   +4 more
doaj   +1 more source