Action of Thionyl Chloride on Carboxylic Acids in Presence of Pyridine [PDF]
Nature, 1946 THE catalytic effect of small amounts of pyridine in the reaction between thionyl chloride and carboxylic acids is well known; Carre and Libermann1 have shown further that it is of great advantage to use equimolar quantities of acid, pyridine, and thionyl chloride, the acid chloride then being formed rapidly at lower temperatures, in high yield.
J P E, HUMAN, J A, MILLS
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Effects of solvent and structure on the reactivity of 6-substituted nicotinic acids with diazodiphenylmethane in aprotic solvents [PDF]
Journal of the Serbian Chemical Society, 2009 The rate constants for the reactions of diazodiphenylmethane (DDM) with 6-substituted nicotinic acids in aprotic solvents at 30°C were determined. The obtained second order rate constants in aprotic solvents, together with literature data for benzoic and
Drmanić Saša Ž. +2 more
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Facile Synthesis of Some Novel Pyrido[3', 2': 4, 5]thieno[2,3-b][1,4]thiazine-8-carboxylic Acids
Molecules, 2007 Model tetrahydropyrido[3',2':4,5]thieno[2,3-b][1,4]thiazines 9a-c were synthesized via reductive lactamization, using sodium dithionite, of the respective 2-[(carboxyalkyl)thio]-3-nitro-4,7-dihydrothieno[2,3-b]pyridine-5-carboxylic acids 7a-c. The latter
Salim S Sabri +4 more
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Iron-Catalyzed, Highly Regioselective Synthesis of alpha-Aryl Carboxylic Acids from Styrene Derivatives and CO2 [PDF]
, 2012 The iron-catalyzed hydrocarboxylation of aryl alkenes has been developed using a highly active bench-stable iron(II) precatalyst to give alpha-aryl carboxylic acids in excellent yields and with near-perfect regioselectivity. Using just 1 mol % FeCl2, bis(
Greenhalgh, Mark D., Thomas, Stephen P.
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A Simple Method for Synthesis of Active Esters of Isonicotinic and Picolinic Acids
Molecules, 2001 A method for preparation of the p-nitrophenyl-, N-hydroxysuccinimidyl- and pentafluorophenyl esters of isonicotinic and picolinic acids from the corresponding acids is reported.
Jørn B. Christensen
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Separations, 2021 Natural phenol and phenolic acids are widely distributed in the plant kingdom and the major dietary sources include fruits and beverages derived therefrom.
Alessio Incocciati +4 more
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Organocatalytic Lewis base functionalisation of carboxylic acids, esters and anhydrides via C1-ammonium or azolium enolates [PDF]
, 2014 This tutorial review highlights the organocatalytic Lewis base functionalisation of carboxylic acids, esters and anhydrides via C1-ammonium/azolium enolates.
Morrill, Louis C., Smith, Andrew D.
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Bis(pyridine-3-carboxylic acid-κN)silver(I) perchlorate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2009 In the title compound, [Ag(C(6)H(5)NO(2))(2)]ClO(4), the Ag(I) atom shows an almost linear coordination geometry, defined by two N atoms from two pyridine-3-carboxylic acid ligands. The complex cations are linked by hydrogen bonds between the carboxyl groups into a chain.
Nie, Xiao-Yan, Li, Qian-Zhu
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Chemistry of Heterocyclic Compounds, 1966 A number of amides and hydrazides of 4-phenyl-2,5-pyridine dicarboxylic acids are synthesized. © 1966 The Faraday Press, Inc.
Prostakov N.S. +3 more
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Synthesis of α-hydroxy-β,β-difluoro-γ-ketoesters via [3,3]sigmatropic rearrangements [PDF]
, 2000 Readily available γ,γ-difluorinated allylic alcohols obtained from trifluoroethanol were esterified efficiently. Exposure to strong base (LDA) afforded the ester enolates, in which chelation both controlled configuration and stabilised against ...
Broadhurst, Michael +3 more
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