Convenient approaches to the synthesis of 6-amino- and 6-oxoimidazo[4,5-b]pyrazolo[3,4-e]pyridines
Aim. To develop convenient approaches to the synthesis of 6-amino- and 6-oxoimidazo[4,5-b]pyrazolo[3,4-e]pyridines as promising biologically active scaffolds. Results and discussion.
Georgiy G. Yakovenko, Mikhailo V. Vovk
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Amides, anhydrides, esters, and thioesters of 2H-azirine-2-carboxylic acids were prepared by a rapid procedure at room temperature involving FeCl2-catalyzed isomerization of 5-chloroisoxazoles to 2H-azirine-2-carbonyl chlorides, followed by reaction with
Anastasiya V. Agafonova +2 more
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Effects of solvent and structure on the reactivity of 6-substituted nicotinic acids with diazodiphenylmethane in aprotic solvents [PDF]
The rate constants for the reactions of diazodiphenylmethane (DDM) with 6-substituted nicotinic acids in aprotic solvents at 30°C were determined. The obtained second order rate constants in aprotic solvents, together with literature data for benzoic and
Drmanić Saša Ž. +2 more
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The effects of solvents and structure on the electronic absorption spectra of the isomeric pyridine carboxylic acid N-oxides [PDF]
The ultraviolet absorption spectra of the carboxyl group of three isomeric pyridine carboxylic acids N-oxides (picolinic acid N-oxide, nicotinic acid N-oxide and isonicotinic acid N-oxide) were determined in fourteen solvents in the wavelength range ...
Drmanić Saša Ž. +4 more
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2-(Carboxymethylsulfanyl)pyridine-3-carboxylic acid monohydrate [PDF]
The title compound, C(8)H(7)NO(4)S·H(2)O, was obtained by reaction of 2-mercaptopyridine-3-carboxylic acid with chloro-acetic acid. In the mol-ecular structure, the dihedral angle between the two least-squares planes defined by the pyridine ring and the carb-oxy group is 8.32 (9)°.
Xiao-Juan Wang, Yun-Long Feng
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A Simple Method for Synthesis of Active Esters of Isonicotinic and Picolinic Acids
A method for preparation of the p-nitrophenyl-, N-hydroxysuccinimidyl- and pentafluorophenyl esters of isonicotinic and picolinic acids from the corresponding acids is reported.
Jørn B. Christensen
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Natural phenol and phenolic acids are widely distributed in the plant kingdom and the major dietary sources include fruits and beverages derived therefrom.
Alessio Incocciati +4 more
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Recurrence of Carboxylic Acid−Pyridine Supramolecular Synthon in the Crystal Structures of Some Pyrazinecarboxylic Acids [PDF]
X-ray crystal structures of pyrazinic acid 1 and isomeric methylpyrazine carboxylic acids 2−4 are analyzed to examine the occurrence of carboxylic acid−pyridine supramolecular synthon V in these heterocyclic acids. Synthon V, assembled by (carboxyl)O−H···
Ashwini Nangia (1400761) +2 more
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Reaction of Pyridine Bases with Carboxylic Acids in Benzene [PDF]
Abstract The reaction of pyridine bases with aliphatic monocarboxylic acids has been studied by means of the partition method. Partition was carried out at 25 °C between benzene and 0.10 mol dm−3 (Na, H) ClO4 aqueous solution, the total concentration of pyridine base and that of carboxylic acid being less than 2×10−2 mol dm−3 and 1.0 mol
Katsumi Hirose, Motoharu Tanaka
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Vanadium. Part IX. Oxo-Vanadium (IV) Complexes of Pyridine Carboxylic Acids [PDF]
The paper describes a number of Oxo-vanadium (IV) complexes of pyridine mono-, di- and tri-carboxylic acids. Pyridine 2-carboxylic acid produces (I) [VO (H2O) (Pic)2 blue, (2) [VO(X) (Pic)2] (where X=pyridine, aniline, α-picoline etc), green and (3) [VO ...
S. Ghosh, R. L. Dutta
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