Results 61 to 70 of about 36,154 (290)

Site-Selective Electrochemical C–H Silylations of Pyridines Enabled by Temporary Reductive Dearomatization [PDF]

Site-selective pyridine C–H silylation chemistry is of significant value but remains underdeveloped. In this study, we demonstrated that electron-deficient pyridines are highly selectively reductively silylated at the C4-position under electrochemical ...
Xin-Qi, Hao, Mao-Ping, Song, Xuan, Liu, Tianyuan, Zhang, Hirofumi, Maekawa, Zhihao, Yang   +5 more
core   +2 more sources

An Organic Chemistry Honors Option Focus on 13C Chemical Shift Studies for Substituted Benzenes and 4-Substitued Pyridines: A Historical and Retrospective View of the Data [PDF]

, 2022
The results of a first-year organic chemistry study of 1H and 13C chemical shifts for substituted benzenes and 4-substiuted pyridines is given from a historical perspective.
Madeline, Malfara, John, Tierney, Annie, Jansen   +2 more
core   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Oxidative Aromatization of Some 1,4-Dihydropyridine Derivatives Using Pyritic Ash in Eco-Sustainable Conditions

Chemistry Proceedings, 2023
Hantzsch 1,4-dihydropyridines (Hantzsch 1,4-DHP), have been utilized as starting material in organic synthesis. In addition, several 1,4-DHP based drugs (Nifedipine, Niguldipine, Amlodepine besylate) have been recognized for the treatment of ...
Juan Enrique Tacoronte Morales, Carla Bernal Villavicencio, Xavier Leopoldo Gracia Cervantes, Maria Elizabeth Canchingre, Maria Teresa Cabrera Pedroso   +4 more
doaj   +1 more source

Synthesis of di-, tri-, and tetrasubstituted pyridines from (phenylthio)carboxylic acids and 2-[aryl(tosylimino)methyl]acrylates [PDF]

, 2014
We thank the Royal Society (ADS), Syngenta/EPSRC (DGS), and the EPSRC National Mass Spectrometry Facility at Swansea University.An isothiourea-catalyzed Michael addition–lactamization followed by the sulfide oxidation–elimination/N- to O-sulfonyl ...
O’Riordan, Timothy J. C., Stark, Daniel Graham, Daniel G. Stark, Timothy J. C. O’Riordan (1702189), Smith, Andrew David, Andrew D. Smith, Timothy J. C. O’Riordan, Daniel G. Stark (1702186), Timothy J. C. O'Riordan, Andrew D. Smith (494170)   +9 more
core   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

Platinum(II) complexes based on derivatives of natural chlorins with pyridine-containing chelate groups as prototypes of drugs for combination therapy in oncology

Тонкие химические технологии
Objectives. To synthesize Pt-containing derivatives of natural chlorins as potential agents for the combination therapy in oncology. Platinum compounds are known to occupy an important place as chemotherapeutic agents in the treatment of oncological ...
N. S. Kirin, P. V. Ostroverkhov, M. N. Usachev, K. P. Birin, M. A. Grin   +4 more
doaj   +1 more source

Axitinib, cabozantinib, everolimus, nivolumab, sunitinib and best supportive care in previously treated renal cell carcinoma: a systematic review and economic evaluation

Health Technology Assessment, 2018
Background: Several therapies have recently been approved for use in the NHS for pretreated advanced or metastatic renal cell carcinoma (amRCC), but there is a lack of comparative evidence to guide decisions between them.
Steve J Edwards, Victoria Wakefield, Peter Cain, Charlotta Karner, Kayleigh Kew, Mariana Bacelar, Natalie Masento, Fatima Salih   +7 more
doaj   +1 more source

2-Bromo-5-methylpyridine

IUCrData, 2016
The title compound, C6H6BrN, has half of a molecule in the asymmetric unit, as it sits on a crystallographic plane of symmetry. In the crystal, weak C—H...N interactions link the molecules, forming chains along [100]. No π–π interactions are observed.
Mrittika Roy, James A. Golen, David R. Manke   +2 more
doaj   +1 more source

Polymeric Sorbents as Energy‐Efficient Alternative to Cryogenic Distillation for Light Hydrocarbon Purification

Advanced Materials, EarlyView.
The transition from cryogenic distillation to polymeric sorbents for light hydrocarbon purification is crucial for energy and environmental sustainability. The polymeric sorbents are engineered to separate gas mixtures based on their specific properties.
Kelechi Festus, Ankit Mondal, Suman Mandal, Jazmine Aiya D. Marquez, Arnab Ghosh, Aishi Sikdar, Urme Podder, Ahana Sarkar, Qingsheng Wang, Hong‐Cai Zhou   +9 more
wiley   +1 more source