Results 41 to 50 of about 36,154 (290)
Synthesis of Benzenes from Pyridines via N to C switch [PDF]
The transformation of pyridines into benzene derivatives is described, using a one-pot ANRORC process with soft nucleophiles such as malonate. Triflic anhydride activates the pyridine to ANRORC synthesis of a carbocyclic β-aminoester intermediate, which ...
Michael, Greaney, Aífe, Conboy
core +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
MoleculesFunctionalized imidazo[1,2-α]pyridines are important scaffolds in pharmaceuticals. Herein, we present an efficient 3-sulfonylmethylation protocol for imidazo[1,2-α]pyridines by sodium sulfinates in DMA and H2O (2:1) via an FeCl3-catalyzed three-component
Shengnan Sun +4 more
doaj +1 more source
Discovering the stacking landscape of a pyridine-pyridine system [PDF]
Journal of Molecular Modeling, 2017 Extremely extensive calculations of potential energy surfaces for the parallel-displaced configuration of pyridine dimer systems have been carried out using a dispersion-corrected density functional. Instead of focusing on stationary geometries these calculations provide much deeper insight into the "landscape" of the interaction energies of the ...
openaire +2 more sources
Highly functionalised fused heterocycle synthesis from fluoropyridines [PDF]
, 2006 Current approaches to drug discovery tends to involve the rapid analogue synthesis and testing of small, focused libraries of low molecular weight, structurally similar "drug-like" molecules, often based around heterocyclic core scaffolds.
Cartwright, Matthew William
core
One-pot synthesis of pyridines from 3-aza-1,5-enynes
, 2013 Efficient one-pot transformation of 3-aza-1,5-enynes to poly-substituted pyridines in good to excellent yields has been developed. This reaction involved cyclization of 3-aza-enynes and elimination of sulfinyl acids steps. (C) 2013 Elsevier Ltd.
Wan, Boshun +4 more
core +1 more source
High‐Efficiency Deep Blue Single‐Gaussian Europium(II) Emitters and Their Emitter‐Host Interactions
Advanced Functional Materials, EarlyView.Crown‐ether ligands and carborate anions enable vacuum‐processable Eu(II) emitters with efficient single‐Gaussian deep‐blue luminescence. Combined photophysical and computational analyses reveal that excited‐electron confinement and steric shielding of the europium center jointly govern compatibility with OLED host materials, establishing molecular ...
Mahmoud Soleimani +8 more
wiley +1 more source
COMPARATIVE SOLUBILITIES IN WATER, IN PYRIDINE AND IN AQUEOUS PYRIDINE. [PDF]
Journal of the American Chemical Society, 1917 n ...
openaire +1 more source
Advanced Functional Materials, EarlyView.An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal +21 more
wiley +1 more source
Synthesis of Nitrobenzenes from Pyridines
A pyridine to benzene skeletal-editing system for nitrobenzene synthesis is described. 4-Substituted pyridines undergo one-pot transformation with nitromethane using nonafluorobutanesulfonic anhydride (Nf2O) as activating group, whereas 3-substituted ...
Conboy, Aife, Greaney, Michael
core +7 more sources