Results 21 to 30 of about 36,154 (290)

Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide

Molecules, 2010
Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N-iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total ...
Mark C. Bagley, Christian Glover
doaj   +1 more source

Synthesis, In Vitro Evaluation and Molecular Docking Studies of Novel Thiophenyl Thiazolyl-Pyridine Hybrids as Potential Anticancer Agents

Molecules, 2023
Many literature reports revealed the anticancer activity of pyridine and thiazole derivatives, especially in lung cancer. Therefore, a new series of thiazolyl pyridines linked with thiophene moiety via hydrazone group was prepared by one-pot multi ...
Fayza O. Ashmawy, Sobhi M. Gomha, Magda A. Abdallah, Magdi E. A. Zaki, Sami A. Al-Hussain, Mohamed A. El-desouky   +5 more
doaj   +1 more source

Pyridine-Based Heterocycles. Synthesis of New Pyrido [4',3':4,5]thieno[2,3-d]pyrimidines and Related Heterocycles

Molecules, 2010
The synthesis of the title compounds was achieved using ethyl 2-amino-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (1) as starting material.
Hussein El-Kashef, Abdel-Rahman Farghaly, Ahmed Al-Hazmi, Thierry Terme, Patrice Vanelle   +4 more
doaj   +1 more source

CHEMICAL PROPERTIES AND APPLICATIONS OF NITROPYRIDINES

Siberian Journal of Life Sciences and Agriculture, 2023
Background. Pyridines are one of the most common heterocycles, the derivatives of which are widely used in pharmaceuticals, agrochemistry, and also in the production of new materials.
Evgeniya V. Ivanova, Irina I. Surova, Maria B. Nikishina, Loik G. Mukhtorov, Irina V. Shahkeldyan, Yuri M. Atroshchenko   +5 more
doaj   +1 more source

Synthesis of Some New 1,3,4-Thiadiazole, Thiazole and Pyridine Derivatives Containing 1,2,3-Triazole Moiety

Molecules, 2017
In this study, 1-(5-Methyl-1-(p-tolyl)-1H-1,2,3-triazol-4-yl)ethan-1-one, was reacted with Thiosemicarbazide, alkyl carbodithioate and benzaldehyde to give thiosemicarbazone, alkylidenehydrazinecarbodithioate and 3-phenylprop-2-en-1-one-1,2,3-triazole ...
Nadia A. Abdelriheem, Ali M. M. Mohamed, Abdou O. Abdelhamid   +2 more
doaj   +1 more source

Concise, Gram-Scale Synthesis of Furo[2,3-B]pyridines, with Functional Handles for Chemoselective Cross-Coupling [PDF]

, 2020
A concise 4-step synthesis of furo[2,3-b]pyridines, with handles in the 3 and 5 positions for palladium mediated cross-coupling reactions, is described.
Sean, O\u27Byrne, David, Drewry, Timothy M., Willson, Benjamin J., Eduful   +3 more
core   +1 more source

The Synthesis of Diverse Annulated Pyridines with 6-Membered Functionalized Saturated Cycles for Medical Chemistry Research

Журнал органічної та фармацевтичної хімії, 2023
The article describes a set of pyridines annulated with functionalized 6-membered saturated rings, which are attractive building blocks for the synthesis of diversified compound libraries in medical chemistry.
Dmytro V. Yehorov, Andrii I. Subota
doaj   +1 more source

Synthesis of Chitosan-La₂O₃ Nanocomposite and Its Utility as a Powerful Catalyst in the Synthesis of Pyridines and Pyrazoles

Molecules, 2021
Recently, the development of nanocatalysts based on naturally occurring polysaccharides has received a lot of attention. Chitosan (CS), as a biodegradable and biocompatible polysaccharide, is considered to be an excellent template for the design of a ...
Khaled D. Khalil, Sayed M. Riyadh, Mariusz Jaremko, Thoraya A. Farghaly, Mohamed Hagar   +4 more
doaj   +1 more source

Tandem Dearomatization/Enantioselective Allylic Alkylation of Pyridines

, 2023
Herein, we report a multistep one-pot reaction of substituted pyridines leading to N-protected tetrahydropyridines with outstanding enantioselectivity (up to 97% ee). An iridium(I)-catalyzed dearomative 1,2-hydrosilylation of pyridines enables the use of
Brian M. Stoltz (1297560), Tyler Casselman (15801070), Lars Süße (15801067), Steffen Greßies (3207240)   +3 more
core   +1 more source

Effect of Atomic Charge and Some Physical Properties on pKa of Substituted Pyridines [PDF]

مجلة التربية والعلم, 1970
A number of different levels of theoretical calculations have been used for assigning the Mulliken charge to the atoms of mono-substituted pyridines, including both quantum chemical and empirical schemes.
Mahmmoud S. Saieed, Zaheda A. Najim
doaj   +1 more source