Results 31 to 40 of about 36,154 (290)

Intramolecular carbolithiation of N-allyl-ynamides: an efficient entry to 1,4-dihydropyridines and pyridines – application to a formal synthesis of sarizotan

Beilstein Journal of Organic Chemistry, 2012
We have developed a general synthesis of polysubstituted 1,4-dihydropyridines and pyridines based on a highly regioselective lithiation/6-endo-dig intramolecular carbolithiation from readily available N-allyl-ynamides.
Wafa Gati, Mohamed M. Rammah, Mohamed B. Rammah, Gwilherm Evano   +3 more
doaj   +1 more source

Synthesis, Molecular Docking Study, and Cytotoxicity Evaluation of Some Novel 1,3,4-Thiadiazole as Well as 1,3-Thiazole Derivatives Bearing a Pyridine Moiety

Molecules, 2022
Pyridine, 1,3,4-thiadiazole, and 1,3-thiazole derivatives have various biological activities, such as antimicrobial, analgesic, anticonvulsant, and antitubercular, as well as other anticipated biological properties, including anticancer activity.
Amr S. Abouzied, Jehan Y. Al-Humaidi, Abdulrahman S Bazaid, Husam Qanash, Naif K. Binsaleh, Abdulwahab Alamri, Sheikh Muhammad Ibrahim, Sobhi M. Gomha   +7 more
doaj   +1 more source

Metastable Transitions in Pyridine and Pyridine Derivatives [PDF]

Zeitschrift für Naturforschung A, 1981
The kinetic energy released in metastable transitions in pyridine, 2, 3, 4 acetylpyridine and 2, 3, 4 aminopyridine differs for the different isomers. This indicates that the dissociation path-way of these compounds depends on the position of the nitrogen atom in the isomer.
Th. M. El-Sherbini, M. D. Migahed, A. M. Shehap   +2 more
openaire   +1 more source

Rhodium(III)-Catalyzed C(sp²)–H Functionalization of Cyclobutenes. Access to Cyclobuta[c]pyridones and -pyridines

, 2019
O-(ω-Alkynyl) hydroxamates derived from cyclobutenyl carboxylic acids were identified as viable substrates in intramolecular rhodium­(III)-catalyzed heteroannulations, which led to diversely substituted cyclobuta­[c]­pyridones.
Janine Cossy, Christophe Meyer (487051), Tomas J. Saiegh, Henri Chédotal, Christophe Meyer, Tomas J. Saiegh (7464839), Henri Chédotal (7464842), Janine Cossy (1457317)   +7 more
core   +1 more source

Electron-Deficient Acetylenes as Three-Modal Adjuvants in S_N^H Reaction of Pyridinoids with Phosphorus Nucleophiles

Molecules, 2021
Publications covering a new easy metal-free functionalization of pyridinoids (pyridines, quinolines, isoquinolines, acridine) under the action of the system of electron-deficient acetylenes (acetylenecarboxylic acid esters, acylacetylenes)/P-nucleophiles
Boris A. Trofimov, Pavel A. Volkov, Anton A. Telezhkin   +2 more
doaj   +1 more source

From Pyridine to (−)‐Agelastatin A

Advanced Synthesis & Catalysis, 2023
Abstract(−)‐Agelastatin A was synthetized employing a flow photorearrangement of a pyridinium salt, constructing in one step the cyclopentene core possessing the desired functionalities and relative configurations. A flow enzymatic kinetic resolution of the resulting bicyclic vinyl aziridine delivered the enantiopure precursor to the natural product ...
Vale, João R., Fortunato, Milene A. G., Andrade, Késsia H. S., Rocha, Ângelo M. R., Afonso, Carlos, Siopa, Filipa   +5 more
openaire   +4 more sources

Cycloalkenopyridines by ring transformations of diazines and triazines [PDF]

, 2007
This paper is a short review on the synthesis of 2,3-cycloalkenopyridines and 3,4-cycloalkenopyridines by inter- and intra-molecular ...
Plas, H.C., van der, van der Plas, H.C., H.C. van der Plas   +2 more
core   +1 more source

New Pyridine Derivatives from Essential Oils

CHIMIA, 1992
Four new pyridines 1–4 have been isolated from jonquil absolute and their structures confirmed by synthesis. These pyridines also occur in other essential oils.
Bruno Maurer, Arnold Hauser
doaj   +2 more sources

Introduction of the difluoromethyl group at the meta- or para-position of pyridines through regioselectivity switch

Nature Communications
Difluoromethyl pyridines have gained significant attention in medicinal and agricultural chemistry. The direct C−H-difluoromethylation of pyridines represents a highly efficient economic way to access these azines.
Pengwei Xu, Zhe Wang, Shu-Min Guo, Armido Studer   +3 more
doaj   +1 more source

Über 1-Aza-bicyclo-heptane

CHIMIA, 1976
A simple way to synthesize 7-phenyl-1-aza-bicyclo[2,2,1]heptanes out of 4-benzoyl-pyridines is described. The corresponding 3- benzoyl-pyridines did not yield the expected 7-phenyl-1-azabicyclo [3,1,1] heptanes.
A. Marxer
doaj   +1 more source