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Antimicrobial, Antimalarial, and Antileishmanial Activities of Mono‐ and Bis‐quaternary Pyridinium Compounds [PDF]

open access: yesChemical Biology and Drug Design, 2010
Pyridinium‐based oxime compounds have been utilized worldwide as antidotes following exposure to anticholinesterase agents. In the event of combined chemical and biological incident, it is of vital importance to know the ability of antidotes to provide additional protection against biological threats.
Sandip B Bharate, Charles M Thompson
exaly   +3 more sources
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Quasielastic neutron scattering study of pyridinium cation reorientation in thiourea pyridinium nitrate inclusion compound

The Journal of Chemical Physics, 2008
The dynamics of the pyridinium cation in thiourea pyridinium nitrate inclusion compound has been studied using quasielastic neutron scattering in a wide temperature range (10–350K). The elastic incoherent structure factor was determined from neutron backscattering and time-of-flight measurements and its analysis allows to describe in detail the ...
A, Pajzderska, M A, Gonzalez, J, Wasicki
openaire   +2 more sources

Oxidation of Active Methylene Compounds by Pyridinium Chlorochromate

Synthetic Communications, 1988
Abstract 1-Aryl-1,2-diketones 6 have been obtained by pyridinium chlorochromate oxidation of benzylketones 5. In the same way 2-buten-1, 4-olide 2 and 3H-benzofuran-2-one 4 have been obtained.
Francesco Bonadies, Carlo Bonini
openaire   +1 more source

Excited-state dynamics of thiophene substituted betaine pyridinium compounds

Phys. Chem. Chem. Phys., 2014
This work deals with the photophysics of novel pyridinium betaine based on 2-pyridin-1-yl-1H-benzimidazole (SBPa) substituted symmetrically by mono- (Th2SBPa) and bi-thiophene fragments (Th4SBPa). The study is based on a combination of steady-state, femtosecond transient absorption spectroscopic measurements supported by PCM-(TD)DFT calculations. It is
Aloïse, S.   +8 more
openaire   +2 more sources

1,1′-Alkylene bis-pyridinium compounds as pickling inhibitors

Corrosion Science, 1990
The inhibition efficiencies of 1,1′-alkylene bis-pyridinium compounds have been studied for corrosion of mild steel in 0.5 M H2SO4. Substitution in the pyridine ring (R = CH3, COOH etc.) has a pronounced effect on the inhibition efficiency, though the length of the alkyl chain bound to the quaternary nitrogen atom is markedly reduced.
G. Subramaniam   +2 more
openaire   +1 more source

2D and 3D Quantitative Structure-Activity Relationship Studies on a Series ofbis-Pyridinium Compounds as Choline Kinase Inhibitors

open access: yesQSAR and Combinatorial Science, 2006
Two-dimensional (2D) and three-dimensional (3D) quantitative structure activity relationship (QSAR) studies have been carried out on a series of 55 bis-pyridinium compounds to find out the structural requirements of choline kinase (ChoK) inhibitors.
G Narahari Sastry
exaly   +2 more sources

On the reported pyridinium pentachlorothallate(III) and some related compounds

Inorganica Chimica Acta, 1984
Abstract While (C 5 H 6 N) 2 TlCl 5 cannot be prepared in water via the reported procedure it may be obtained in non-aqueous media. Although its low-energy infrared spectrum contains broad peaks and the Raman spectrum is deceptively simple, comparison of these spectra with those of other TlCl 4 − , TlCl 5 3− and TlCl 6 3− derivatives shows that
Mary B. Millikan, Bruce D. James
openaire   +1 more source

Formation of quaternary pyridinium compounds by the action of glutaraldehyde on proteins

Journal of the Chemical Society, Chemical Communications, 1976
1-(5-Amino-5-carboxypentyl)pyridinium chloride hydrochloride (2) has been isolated by acid hydrolysis of the product of the action of glutaraldehyde on ovalbumin, supporting the view that the chromophore with λmax ca. 265 nm formed when glutaraldehyde reacts with proteins is due to the formation of quaternary pyridinium compounds.
Paul M. Hardy   +2 more
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Antithrombotic Effects of Pyridinium Compounds Formed from Trigonelline upon Coffee Roasting

Journal of Agricultural and Food Chemistry, 2014
Coffee may exert a preventive effect on arterial thrombosis. Trigonelline is one of the most abundant compounds in coffee that undergoes pyrolysis upon roasting of coffee beans. The aim of the present study was to identify pyridinium compounds formed upon trigonelline pyrolysis and coffee roasting and to investigate the effect of three of them, i.e., 1-
Bartlomiej Kalaska   +2 more
exaly   +3 more sources

Secondary interactions in the isomorphous compounds 2,6-bis(chloromethyl)pyridinium chloride and 2,6-bis(bromomethyl)pyridinium bromide

Acta Crystallographica Section C Crystal Structure Communications, 2004
The title compounds, C7H8Cl2N+.Cl- and C7H8Br2N+.Br-, are isomorphous. In the crystal packing, layers parallel to the ac plane are formed by a classical N(+)-H...X- hydrogen bond (X = halogen) and two X...X contacts. A third X...X contact links the layers, and a fourth, which is however very long, completes a ladder-like motif of halogen atoms ...
Virginia, Lozano, Peter G, Jones
openaire   +2 more sources

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