Results 51 to 60 of about 22,841 (254)

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Regulation of Crystallization Kinetics via Zwitterionic Additive for Efficient and Operationally Stable Formamidinium Perovskite Solar Cells

Advanced Energy Materials, EarlyView.
This study introduces a zwitterionic additive, Cl‐PPS, to regulate crystallization kinetics and passivate defects in formamidinium‐based perovskite solar cells. Cl‐PPS promotes direct α‐phase formation, minimizes necessary MACl loading, and induces highly crystalline, vertically oriented grains.
Shuai Li, Bohong Chang, Jianqiu Gong, Xianglang Sun, Francesco Vanin, Chunlei Zhang, Zexin Yu, Ning Wang, Dong Zhang, Baoze Liu, Liangchen Qian, Xinhui Lu, Haipeng Lu, Mingjie Li, Danpeng Gao, Bo Li, Zonglong Zhu   +16 more
wiley   +1 more source

Structure and Spectroscopic Characterisation of Phenanthroline‐Based Iodobismuthate(III) Complexes Utilised for Raw Acoustic Signal Classification

Advanced Intelligent Discovery, EarlyView.
Memristors based on trimethylsulfonium (phenanthroline)tetraiodobismuthate have been utilised as a nonlinear node in a delayed feedback reservoir. This system allowed an efficient classification of acoustic signals, namely differentiation of vocalisation of the brushtail possum (Trichosurus vulpecula).
Ewelina Cechosz, Gisya Abdi, Andrzej Sławek, Marlena Gryl, Konrad Szaciłowski   +4 more
wiley   +1 more source

ELECTROCHEMICAL BEHAVIOUR OF THE NEW HETEROCYCLIC PYRIDINIUM LIGANDS

Studia Universitatis Babes-Bolyai Chemia, 2015
New heterocyclic pyridinium compounds as N,N’ di-(p-bromophenacyl)-4,4’-bipyridinium dibromide (Lr) and N,N’ di-(p-bromophenacyl)-1,2-bis(4-pyridinium)-ethane dibromide (Lm) were investigated applying cyclic voltammetry to evaluate the electrochemical ...
Andreea CÂRÂC, Rica BOSCENCU, Rodica Mihaela DINICĂ, Geta CÂRÂC   +3 more
doaj  

Data for the cytotoxicity, self-assembling properties and synthesis of 4-pyridinium-1,4-dihydropyridines

Data in Brief, 2020
In this data file the synthetic procedures for preparation of the original 4-pyridinium-1,4-dihydropyridines (4-Py-1,4-DHP) and their parent compounds – dialkyl 2,6-dimethyl-4-(3-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylates were described. In total, 5
Klavs Pajuste, Martins Rucins, Ilona Domracheva, Arkadij Sobolev, Nadiia Pikun, Mara Plotniece, Gunars Duburs, Karlis Pajuste, Aiva Plotniece   +8 more
doaj   +1 more source

Investigating the chemistry of pyridinium ylides [PDF]

, 2018
This thesis describes investigation into catalytic formation of pyridinium ylides from diazo compounds and their subsequent reactivity. In particular, cycloaddition reactions with electrophilic alkenes are performed to generate tetrahydroindolizines that
Abdullah, Rasha Azzam
core  

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Pyridinium containing sulfonamides have been largely investigated as carbonic anhydrase inhibitors (CAIs), showing interesting selectivity features. Nevertheless, only few structural studies are so far available on adducts that these compounds form with ...
Vincenzo Alterio, Davide Esposito, Simona Maria Monti, Claudiu T. Supuran, Giuseppina De Simone   +4 more
doaj   +1 more source

Simplexidine, a 4-Alkylpyridinium Alkaloid from the Caribbean Sponge Plakortis simplex

Molecules, 2008
Chemical analysis of the secondary metabolites of the Caribbean sponge Plakortis simplex, a source of many bioactive compounds, showed the presence of the new metabolite simplexidine (4), belonging to the extremely rare class of 4-alkyl-pyridinium ...
Orazio Taglialatela-Scafati, Fernando Scala, Adriana Romano, Ernesto Fattorusso   +3 more
doaj   +1 more source

Sydnone C-4 heteroarylation with an indolizine ring via Chichibabin indolizine synthesis

Beilstein Journal of Organic Chemistry, 2016
The synthesis of sydnones heteroarylated at C-4 with an indolizine was achieved by Chichibabin (Tschitschibabin) indolizine synthesis starting from the corresponding sydnone-N-pyridinium bromides.
Florin Albota, Mino R. Caira, Constantin Draghici, Florea Dumitrascu, Denisa E. Dumitrescu   +4 more
doaj   +1 more source