Electron-deficient pyridinium salts/thiourea cooperative catalyzed O-glycosylation via activation of O-glycosyl trichloroacetimidate donors [PDF]
Beilstein Journal of Organic Chemistry, 2017 The glycosylation of O-glycosyl trichloroacetimidate donors using a synergistic catalytic system of electron-deficient pyridinium salts/aryl thiourea derivatives at room temperature is demonstrated. The acidity of the adduct formed by the 1,2-addition of
Mukta Shaw +3 more
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One-Pot Phosphate-Mediated Synthesis of Novel 1,3,5-Trisubstituted Pyridinium Salts: A New Family of S. aureus Inhibitors. [PDF]
Molecules, 2017 Polysubstituted pyridinium salts are valuable pharmacophores found in many biologically active molecules. Their synthesis typically involves the use of multistep procedures or harsh reaction conditions.
Pesnot T +4 more
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Asymmetric Hydrogenation of 3‐Substituted Pyridinium Salts [PDF]
Chemistry – A European Journal, 2016 AbstractThe use of an equivalent amount of an organic base leads to high enantiomeric excess in the asymmetric hydrogenation of N‐benzylated 3‐substituted pyridinium salts into the corresponding piperidines. Indeed, in the presence of Et3N, a Rh‐JosiPhos catalyst reduced a range of pyridinium salts with ee values up to 90 %.
M. Renom-Carrasco +6 more
openaire +5 more sources
Regioselective and site-divergent synthesis of tetrahydropyridines by controlled reductive-oxidative dearomative hydroarylation of pyridinium salts [PDF]
Nature CommunicationsTetrahydropyridine skeletons serve as ubiquitous structural motifs which are predominant in natural products, bioactive and drug molecules. Thus, the development of efficient and general synthetic methods for the synthesis of tetrahydropyridine ...
Xing-Fu Wei +4 more
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Antitumour Effects of Selected Pyridinium Salts on Sensitive Leukaemia HL60 Cells and Their Multidrug Resistant Topoisomerase II-Defective HL60/MX2 Counterparts [PDF]
Molecules, 2022 Multidrug resistance (MDR), having a multifactorial nature, is one of the major clinical problems causing the failure of anticancer therapy. The aim of this study was to examine the antitumour effects of selected pyridinium salts, 1-methyl-3 ...
Jolanta Tarasiuk +2 more
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Rapid Electrophilic Cysteine Arylation with Pyridinium Salts. [PDF]
Bioconjug Chem, 2022 Here, we present a series of fluorinated cationic reagents that enable rapid arylation of cysteine under mild conditions compatible with proteins and peptides. The highly polarized C-F bond and attractive nucleophile-electrophile Coulombic interactions substantially accelerate cysteine arylation, leading to unusually high rate constants on the order of
Lipka BM +9 more
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One‐Step Aqueous Synthesis of Glycosyl Pyridinium Salts, Electrochemical Study, and Assessment of Utility as Precursors of Glycosyl Radicals Using Photoredox Catalysis [PDF]
ChemistryOpenA single step method for the production of unprotected glycosyl pyridinium salts has been developed involving treatment of the unprotected sugar with a pyridine, triethylamine, and either 2‐chloro‐1,3‐dimethylimidazolinium chloride (DMC) or 2‐chloro‐1,3 ...
Daniel Chong +2 more
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Quaternary Pyridinium Salts: A Review
Journal of Oleo Science, 2008 Cationic surfactants are being used in various applications industrially and domestically for a long time. Pyridinium salts come under the category of cationic surfactants. These are unsaturated heterocyclic compounds having different functional groups present either on pyridine ring or at nitrogen atom.
Madaan, Parag, Tyagi, Vinod K.
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Preparation of the Pyridinium Salts Differing in the Length of the N-Alkyl Substituent
Molecules, 2010 Quaternary pyridinium salts with chains ranging from C8 to C20 belong in the large group of cationic surfactants. In this paper, the preparation of such cationic surface active agents based on the pyridinium moiety and differing in the length of the N ...
Kamil Musilek +7 more
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Preparation and Characterization of Polyphenol-Functionalized Chitooligosaccharide Pyridinium Salts with Antioxidant Activity [PDF]
Marine DrugsAs a kind of eco-friendly material with wide application prospects, chitooligosaccharide (COS) has attracted increasing attention because of its unique bioactivities.
Zhen Qi +3 more
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