Formal [1 + 2 + 3] Annulation of Anilines and CF<sub>3</sub>‑Containing Ynones via 6π-Electrocyclization. [PDF]
Feng L +7 more
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Iminopyridonato Iridium Complexes: <i>O</i>-Functionalization via C-X Bond Cleavage. [PDF]
Moždiak O +4 more
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Phenotypic screening of human iPSC-derived neurons identifies thienopyridones as neuritogenic small molecules. [PDF]
Imamura K +13 more
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CD109 Drives Stemness and Chemoresistance in Colorectal Cancer via LRRC8A/AKAP12/PKCα-Mediated STAT3 Activation and WNT Signaling. [PDF]
Bartolomé RA +16 more
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Antiproliferative Potential of Cobalt(II) Phenanthroline Complexes with Pyridonates. [PDF]
Nikiforova ME +8 more
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Pyridones as Potential Antitumor Agents II: 4-Pyridones and Bioisosteres of 3-Acetoxy-2-pyridone
Journal of Pharmaceutical Sciences, 1980Pyridone structural requirements for activity against murine P-388 leukemia have been extended to isosteric analogs of 3-hydroxy-4-pyridone, a compound previously found to have activity. An amino group can be substituted for the 3-hydroxyl function with retention of activity.
D R, Hwang, G R, Proctor, J S, Driscoll
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ChemInform Abstract: PHOTOISOMERIZATION OF 4‐PYRIDONES TO 2‐PYRIDONES
Chemischer Informationsdienst, 1974AbstractBestrahlung (Hg‐Mitteldrucklampe) der 4‐Pyridone (I) liefert die isomeren 2‐Pyridone (II) als Hauptprodukte, während die 4‐Pyridone (III) unter gleichen Bedingungen unverändert bleiben.
NOBUYUKI ISHIBE, JUN MASUI
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Lithiation of 1-methyl-4-pyridone with n-butyl-lithium at -78 °C proceeds smoothly at the C-2 position and 2-substituted-4-pyridones (1c–j) are obtained by subsequent reaction with electorphiles; lithiation of 1-methyl-2-pyridone takes place predominantly at the N-methyl, the lithio-derivative reacting rapidly, even at -78 °C with starting pyridone to ...
Premji Patel, John A. Joule
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Ambident Reactivities of Pyridone Anions
Journal of the American Chemical Society, 2010The kinetics of the reactions of the ambident 2- and 4-pyridone anions with benzhydrylium ions (diarylcarbenium ions) and structurally related Michael acceptors have been studied in DMSO, CH(3)CN, and water. No significant changes of the rate constants were found when the counterion was varied (Li(+), K(+), NBu(4)(+)) or the solvent was changed from ...
Martin, Breugst, Herbert, Mayr
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Photoisomerization of 4-pyridones to 2-pyridones
Journal of the American Chemical Society, 1974Nobuyuki Ishibe, Jun Masui
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